Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of IolR in Streptomyces avermitilis MA-4680

Properties
Regulator type: Transcription factor
TF locus tag: SAV_7146, SAV_1984
Regulator family: GntR/Others
Regulation mode:
Biological process: Inositol utilization
Effector:
Regulog: IolR - Streptomycetaceae
Statistics of regulated genes:
- Genes 24
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 35 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -75
Score: 3
Sequence: CCGATGTCCGGATGCACG
Locus tag: SAV_1983
Name: iolTA2
Funciton: Inositol ABC transport system, sugar-binding protein
Locus tag: SAV_1982
Name: iolTB2
Funciton: Inositol ABC transport system, permease protein
Locus tag: SAV_1981
Name: iolTC2
Funciton: Inositol ABC transport system, ATP-binding protein
iolTA2
Inositol ABC transport system, sugar-binding protein
iolTB2
Inositol ABC transport system, permease protein
iolTC2
Inositol ABC transport system, ATP-binding protein

Position: -78
Score: 4.8
Sequence: CGAATGTCTGGACAAAAC
Locus tag: SAV_5338
Name: iolC
Funciton: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)
Locus tag: SAV_5339
Name: iolJ
Funciton: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
Locus tag: SAV_5340
Name: iolB
Funciton: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)
Locus tag: SAV_5341
Name: iolD
Funciton: Epi-inositol hydrolase (EC 3.7.1.-)
Locus tag: SAV_5342
Name: iolA
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
iolC
5-keto-2-deoxygluconokinase (EC 2.7.1.92)
iolJ
5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
iolB
5-deoxy-glucuronate isomerase (EC 5.3.1.-)
iolD
Epi-inositol hydrolase (EC 3.7.1.-)
iolA
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)

Position: -147
Score: 4.5
Sequence: ACTTTGTTAAGACATCAT
Position: -115
Score: 5.1
Sequence: CGAATGTCCGTACAAACT
Locus tag: SAV_7150
Name: iolC
Funciton: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)
Locus tag: SAV_7149
Name: iolJ
Funciton: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
Locus tag: SAV_7148
Name: iolB
Funciton: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)
Locus tag: SAV_7147
Name: iolD
Funciton: Epi-inositol hydrolase (EC 3.7.1.-)
Locus tag: SAV_7146
Name: iolR
Funciton: Inositol utilization transcriptional regulator, GntR family
iolC
5-keto-2-deoxygluconokinase (EC 2.7.1.92)
iolJ
5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
iolB
5-deoxy-glucuronate isomerase (EC 5.3.1.-)
iolD
Epi-inositol hydrolase (EC 3.7.1.-)
iolR
Inositol utilization transcriptional regulator, GntR family

Position: -79
Score: 5.1
Sequence: GGTTTGTCCGGACAACCG
Locus tag: SAV_1984
Name: iolR1
Funciton: Inositol utilization transcriptional regulator, GntR family
Locus tag: SAV_1983
Name: iolTA
Funciton: Inositol ABC transport system sugar-binding protein
Locus tag: SAV_1982
Name: iolTB
Funciton: Inositol ABC transport system permease protein
Locus tag: SAV_1981
Name: iolTC
Funciton: Inositol ABC transport system ATP-binding protein
Locus tag: SAV_1980
Name: SCO6259
Funciton: Putative sugar kinase
iolR1
Inositol utilization transcriptional regulator, GntR family
iolTA
Inositol ABC transport system sugar-binding protein
iolTB
Inositol ABC transport system permease protein
iolTC
Inositol ABC transport system ATP-binding protein
SCO6259
Putative sugar kinase

Position: -55
Score: 5.1
Sequence: CGGTTGTCCGGACAAACC
Locus tag: SAV_1985
Name: iolG
Funciton: Inositol 2-dehydrogenase (EC 1.1.1.18 )
iolG
Inositol 2-dehydrogenase (EC 1.1.1.18 )

Position: -210
Score: 5.1
Sequence: AGTTTGTACGGACATTCG
Position: -178
Score: 4.5
Sequence: ATGATGTCTTAACAAAGT
Locus tag: SAV_7151
Name: iolTA2
Funciton: Inositol ABC transport system sugar-binding protein
Locus tag: SAV_7152
Name: iolTB2
Funciton: Inositol ABC transport system permease protein
Locus tag: SAV_7153
Name: iolTC2
Funciton: Inositol ABC transport system ATP-binding protein
Locus tag: SAV_7154
Name: iolE2
Funciton: Inosose dehydratase (EC 4.2.1.44)
iolTA2
Inositol ABC transport system sugar-binding protein
iolTB2
Inositol ABC transport system permease protein
iolTC2
Inositol ABC transport system ATP-binding protein
iolE2
Inosose dehydratase (EC 4.2.1.44)

Position: -72
Score: 4.8
Sequence: GTTTTGTCCAGACATTCG
Locus tag: SAV_5337
Name: iolE
Funciton: Inosose dehydratase (EC 4.2.1.44)
iolE
Inosose dehydratase (EC 4.2.1.44)
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD