Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CodY in Streptococcus thermophilus CNRZ1066

Properties
Regulator type: Transcription factor
TF locus tag: str1635
Regulator family: CodY
Regulation mode: repressor (activator)
Biological process: Amino acid metabolism
Effector: Guanosine triphosphate; Branched-chain amino acids
Regulog: CodY - Streptococcaceae
Statistics of regulated genes:
- Genes 45
- Operons 24
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 273 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -81
Score: 4.9
Sequence: AATATTTTGACAATT
Locus tag: str0645
Name: aroA
Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
Locus tag: str0646
Name: aroK
Funciton: Shikimate kinase I (EC 2.7.1.71)
Locus tag: str0647
Name: pheA
Funciton: Prephenate dehydratase (EC 4.2.1.51)
aroA
5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
aroK
Shikimate kinase I (EC 2.7.1.71)
pheA
Prephenate dehydratase (EC 4.2.1.51)

Position: -106
Score: 5
Sequence: ATTTTTCAGAAAATA
Position: -33
Score: 5.2
Sequence: ATTATTCTGAAAATT
Locus tag: str0745
Name: SMU.1109
Funciton: Predicted Mn2+/Fe2+ transporter, NRAMP family
SMU.1109
Predicted Mn2+/Fe2+ transporter, NRAMP family

Position: -59
Score: 5.4
Sequence: AATTTTCTGACAATT
Locus tag: str1878
Name: thrC
Funciton: Threonine synthase (EC 4.2.3.1)
thrC
Threonine synthase (EC 4.2.3.1)

Position: -90
Score: 4.9
Sequence: AATTGTCAGAATTTT
Locus tag: str0590
Name: ilvE
Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
ilvE
Branched-chain amino acid aminotransferase (EC 2.6.1.42)

Position: -52
Score: 5
Sequence: AAGATTCTGAAAATT
Locus tag: str0430
Name: gdhA
Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
gdhA
NADP-specific glutamate dehydrogenase (EC 1.4.1.4)

Position: -76
Score: 4.7
Sequence: AATTTTCTGATAAAA
Locus tag: str1445
Name: oppA2
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppA2
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)

Position: -194
Score: 4.6
Sequence: ATTTTTTAGAAAATA
Position: -121
Score: 4.9
Sequence: ATTATTCTGAAAAAT
Locus tag: str1443
Name: oppA2
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Locus tag: str1442
Name: oppA2
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Locus tag: str1441
Name: oppB2
Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
Locus tag: str1440
Name: oppC2
Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
Locus tag: str1439
Name: oppD2
Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
Locus tag: str1438
Name: oppF2
Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
oppA2
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppA2
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppB2
Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
oppC2
Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
oppD2
Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
oppF2
Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)

Position: -45
Score: 5.2
Sequence: AATTATCAAAAAATT
Locus tag: str0494
Name: nrgA
Funciton: Ammonium transporter
Locus tag: str0495
Name: nrgB
Funciton: Nitrogen regulatory protein P-II
nrgA
Ammonium transporter
nrgB
Nitrogen regulatory protein P-II

Position: -89
Score: 5
Sequence: AATTTTCTGAATACT
Locus tag: str1263
Name: gapN
Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
gapN
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)

Position: -27
Score: 5.2
Sequence: AATTTTTAGATAATT
Locus tag: str1873
Name: ilvB
Funciton: Acetolactate synthase large subunit (EC 2.2.1.6)
Locus tag: str1872
Name: ilvN
Funciton: Acetolactate synthase small subunit (EC 2.2.1.6)
Locus tag: str1871
Name: ilvC
Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86)
ilvB
Acetolactate synthase large subunit (EC 2.2.1.6)
ilvN
Acetolactate synthase small subunit (EC 2.2.1.6)
ilvC
Ketol-acid reductoisomerase (EC 1.1.1.86)

Position: -60
Score: 5.4
Sequence: ATTTTTCTGAAAATT
Locus tag: str0150
Name: ilvA
Funciton: Threonine dehydratase (EC 4.3.1.19)
ilvA
Threonine dehydratase (EC 4.3.1.19)

Position: -132
Score: 5.4
Sequence: AATTTTCAGACAATT
Locus tag: str1635
Name: codY
Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family
Locus tag: str1634
Name: pncA
Funciton: Nicotinamidase (EC 3.5.1.19)
codY
Nutrient limitation global transcriptional regulator CodY, CodY family
pncA
Nicotinamidase (EC 3.5.1.19)

Position: -61
Score: 4.7
Sequence: ATTTTTTAGACAATT
Locus tag: str1604
Name: ilvD
Funciton: Dihydroxy-acid dehydratase (EC 4.2.1.9)
ilvD
Dihydroxy-acid dehydratase (EC 4.2.1.9)

Position: -57
Score: 5.1
Sequence: AATTTTCAGAAATTA
Locus tag: str0229
Name: pepC
Funciton: Aminopeptidase C (EC 3.4.22.40)
pepC
Aminopeptidase C (EC 3.4.22.40)

Position: -70
Score: 4.6
Sequence: AATATTCTGTCAATT
Locus tag: str0469
Name: hom
Funciton: Homoserine dehydrogenase (EC 1.1.1.3)
Locus tag: str0470
Name: thrB
Funciton: Homoserine kinase (EC 2.7.1.39)
hom
Homoserine dehydrogenase (EC 1.1.1.3)
thrB
Homoserine kinase (EC 2.7.1.39)

Position: -74
Score: 5.5
Sequence: AAATTTCTGAAAATT
Locus tag: str0280
Name: ureI
Funciton: Urea channel UreI
Locus tag: str0281
Name: ureA
Funciton: Urease gamma subunit (EC 3.5.1.5)
Locus tag: str0282
Name: ureB
Funciton: Urease beta subunit (EC 3.5.1.5)
Locus tag: str0283
Name: ureC
Funciton: Urease alpha subunit (EC 3.5.1.5)
ureI
Urea channel UreI
ureA
Urease gamma subunit (EC 3.5.1.5)
ureB
Urease beta subunit (EC 3.5.1.5)
ureC
Urease alpha subunit (EC 3.5.1.5)

Position: -80
Score: 5
Sequence: AATATTCCGAAAATT
Locus tag: str1199
Name: yfjA
Funciton: Conserved hypothetical protein
yfjA
Conserved hypothetical protein

Position: -38
Score: 4.6
Sequence: AAAATTCAGAATATA
Locus tag: str1777
Name: glnR
Funciton: Nitrogen metabolism transcriptional regulator GlnR, MerR family
Locus tag: str1776
Name: glnA
Funciton: Glutamine synthetase type I (EC 6.3.1.2)
glnR
Nitrogen metabolism transcriptional regulator GlnR, MerR family
glnA
Glutamine synthetase type I (EC 6.3.1.2)

Position: -108
Score: 4.9
Sequence: AAAAGTCAGAAAATT
Locus tag: str0718
Name: ppc
Funciton: Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
ppc
Phosphoenolpyruvate carboxylase (EC 4.1.1.31)

Position: -171
Score: 4.6
Sequence: AAAGTTCTAAAAATT
Locus tag: str1868
Name: rpoB
Funciton: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
Locus tag: str1867
Name: rpoC
Funciton: DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
rpoB
DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
rpoC
DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)

Position: -53
Score: 4.5
Sequence: CGTTTTCAGAAAATT
Locus tag: str1297
Name: dapA
Funciton: Dihydrodipicolinate synthase (EC 4.2.1.52)
dapA
Dihydrodipicolinate synthase (EC 4.2.1.52)

Position: -56
Score: 5.1
Sequence: AATTATCAGAATTTT
Locus tag: str0378
Name: thrA
Funciton: Aspartokinase (EC 2.7.2.4)
thrA
Aspartokinase (EC 2.7.2.4)

Position: -108
Score: 4.7
Sequence: AATATTCTGAATTAT
Locus tag: str0509
Name: aapA
Funciton: Amino acid permease
aapA
Amino acid permease

Position: -65
Score: 5.6
Sequence: AATTTTCTGATAATT
Locus tag: str0359
Name: livK
Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
Locus tag: str0360
Name: livH
Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
Locus tag: str0361
Name: livM
Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
Locus tag: str0362
Name: livG
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
Locus tag: str0363
Name: livF
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
livK
Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
livH
Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
livM
Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
livG
Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
livF
Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
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