Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CodY in Streptococcus sanguinis SK36

Properties
Regulator type: Transcription factor
TF locus tag: SSA_0566
Regulator family: CodY
Regulation mode: repressor (activator)
Biological process: Amino acid metabolism
Effector: Guanosine triphosphate; Branched-chain amino acids
Regulog: CodY - Streptococcaceae
Statistics of regulated genes:
- Genes 43
- Operons 21
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 273 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -53
Score: 5.8
Sequence: AATTTTCAGAAAATT
Locus tag: SSA_0774
Name: gapN
Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
gapN
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)

Position: -71
Score: 5.6
Sequence: AATTTTCAGATAATT
Locus tag: SSA_0566
Name: codY
Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family
Locus tag: SSA_0567
Name: pncA
Funciton: Nicotinamidase (EC 3.5.1.19)
codY
Nutrient limitation global transcriptional regulator CodY, CodY family
pncA
Nicotinamidase (EC 3.5.1.19)

Position: -182
Score: 5.5
Sequence: AATTTTTAGAAAATT
Locus tag: SSA_0371
Name: gdhA
Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
gdhA
NADP-specific glutamate dehydrogenase (EC 1.4.1.4)

Position: -98
Score: 5.8
Sequence: AATTTTCTGAAAATT
Locus tag: SSA_1225
Name: ilvE
Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
ilvE
Branched-chain amino acid aminotransferase (EC 2.6.1.42)

Position: -64
Score: 5
Sequence: AATTGTCTGAAAATA
Locus tag: SSA_0321
Name: ubiE
Funciton: SAM-dependent methyltransferase
ubiE
SAM-dependent methyltransferase

Position: -57
Score: 5.2
Sequence: AATTTTCTGATAAAT
Locus tag: SSA_0095
Name: thrC
Funciton: Threonine synthase (EC 4.2.3.1)
thrC
Threonine synthase (EC 4.2.3.1)

Position: -37
Score: 5.5
Sequence: AATTTTTAGAAAATT
Locus tag: SSA_1970
Name: ilvB
Funciton: Acetolactate synthase large subunit (EC 2.2.1.6)
Locus tag: SSA_1969
Name: ilvN
Funciton: Acetolactate synthase small subunit (EC 2.2.1.6)
Locus tag: SSA_1968
Name: ilvC
Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86)
Locus tag: SSA_1967
Name: ilvA
Funciton: Threonine dehydratase (EC 4.3.1.19)
ilvB
Acetolactate synthase large subunit (EC 2.2.1.6)
ilvN
Acetolactate synthase small subunit (EC 2.2.1.6)
ilvC
Ketol-acid reductoisomerase (EC 1.1.1.86)
ilvA
Threonine dehydratase (EC 4.3.1.19)

Position: -78
Score: 5.6
Sequence: AATTATCAGAAAATT
Locus tag: SSA_2165
Name: oppA2
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppA2
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)

Position: -87
Score: 5.6
Sequence: AATATTCTGAAAATT
Locus tag: SSA_1948
Name: oppA2
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Locus tag: SSA_1947
Name: oppB2
Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
Locus tag: SSA_1946
Name: oppC2
Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
Locus tag: SSA_1945
Name: oppD2
Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
Locus tag: SSA_1944
Name: oppF2
Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
oppA2
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppB2
Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
oppC2
Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
oppD2
Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
oppF2
Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)

Position: -30
Score: 5.5
Sequence: AATTTTTTGAAAATT
Locus tag: SSA_1194
Name: asd
Funciton: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
Locus tag: SSA_1193
Name: dapA
Funciton: Dihydrodipicolinate synthase (EC 4.2.1.52)
asd
Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
dapA
Dihydrodipicolinate synthase (EC 4.2.1.52)

Position: -78
Score: 5.3
Sequence: AATCTTCTGAAAATT
Locus tag: SSA_2286
Name: ilvD
Funciton: Dihydroxy-acid dehydratase (EC 4.2.1.9)
ilvD
Dihydroxy-acid dehydratase (EC 4.2.1.9)

Position: 22
Score: 4.5
Sequence: AATTTCCAGAAAATG
Locus tag: SSA_2051
Name: pepF
Funciton: Oligoendopeptidase F
pepF
Oligoendopeptidase F

Position: -290
Score: 4.7
Sequence: AATTTTCATAAAATA
Locus tag: SSA_0363
Name: dagA
Funciton: Sodium/glycine symporter
dagA
Sodium/glycine symporter

Position: -87
Score: 4.5
Sequence: TATATTGAGAAAATT
Locus tag: SSA_0983
Name: yfjA
Funciton: Conserved hypothetical protein
yfjA
Conserved hypothetical protein

Position: -92
Score: 5.1
Sequence: AATTGTCAGACAATT
Locus tag: SSA_1129
Name: efeO
Funciton: Ferrous iron transport periplasmic protein EfeO, contains peptidase-M75 domain and (frequently) cupredoxin-like domain
Locus tag: SSA_1130
Name: efeB
Funciton: Ferrous iron transport peroxidase EfeB
Locus tag: SSA_1131
Name: efeU
Funciton: Ferrous iron transport permease EfeU
Locus tag: SSA_1132
Name: tatC
Funciton: Twin-arginine translocation protein TatC
Locus tag: SSA_1133
Name: tatA
Funciton: Twin-arginine translocation protein TatA
efeO
Ferrous iron transport periplasmic protein EfeO, contains peptidase-M75 domain and (frequently) cupredoxin-like domain
efeB
Ferrous iron transport peroxidase EfeB
efeU
Ferrous iron transport permease EfeU
tatC
Twin-arginine translocation protein TatC
tatA
Twin-arginine translocation protein TatA

Position: -56
Score: 5.4
Sequence: AATTGTCAGAAAATT
Locus tag: SSA_1882
Name: scpC
Funciton: Serine endopeptidase ScpC (EC 3.4.21.-)
scpC
Serine endopeptidase ScpC (EC 3.4.21.-)

Position: -112
Score: 4.6
Sequence: ATTTTTCTAAATTTT
Locus tag: SSA_1724
Name: acuB
Funciton: Acetoin utilization protein AcuB
acuB
Acetoin utilization protein AcuB

Position: -42
Score: 5.3
Sequence: AAAATTCAGAAAATT
Locus tag: SSA_0593
Name: ymdE
Funciton: Conserved hypothetical protein
ymdE
Conserved hypothetical protein

Position: -65
Score: 5.2
Sequence: AATTGTCAGATAATT
Locus tag: SSA_1729
Name: livK
Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
Locus tag: SSA_1728
Name: livH
Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
Locus tag: SSA_1727
Name: livM
Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
Locus tag: SSA_1726
Name: livG
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
Locus tag: SSA_1725
Name: livF
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
livK
Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
livH
Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
livM
Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
livG
Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
livF
Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)

Position: -47
Score: 5.3
Sequence: AATTTTCAGAATTTT
Locus tag: SSA_1943
Name: thrA
Funciton: Aspartokinase (EC 2.7.2.4)
thrA
Aspartokinase (EC 2.7.2.4)

Position: -269
Score: 5.3
Sequence: AATTTTCAGAAAATA
Locus tag: SSA_0975
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: SSA_0977
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: SSA_0978
Name: ygaE
Funciton: Predicted transmembrane protein
Locus tag: SSA_0980
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: SSA_0981
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Locus tag: SSA_0983
Name: yfjA
Funciton: Conserved hypothetical protein
leuA
2-isopropylmalate synthase (EC 2.3.3.13)
leuB
3-isopropylmalate dehydrogenase (EC 1.1.1.85)
ygaE
Predicted transmembrane protein
leuC
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
yfjA
Conserved hypothetical protein
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