Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CodY in Streptococcus pneumoniae TIGR4

Properties
Regulator type: Transcription factor
TF locus tag: SP_1584
Regulator family: CodY
Regulation mode: repressor (activator)
Biological process: Amino acid metabolism
Effector: Guanosine triphosphate; Branched-chain amino acids
Regulog: CodY - Streptococcaceae
Statistics of regulated genes:
- Genes 42
- Operons 20
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 273 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -71
Score: 5.3
Sequence: AAAATTCTGAAAATT
Locus tag: SP_0366
Name: oppA2
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppA2
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)

Position: -87
Score: 5.6
Sequence: AATATTCTGAAAATT
Locus tag: SP_1891
Name: oppA2
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Locus tag: SP_1890
Name: oppB2
Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
Locus tag: SP_1889
Name: oppC2
Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
Locus tag: SP_1888
Name: oppD2
Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
Locus tag: SP_1887
Name: oppF2
Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
oppA2
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppB2
Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
oppC2
Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
oppD2
Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
oppF2
Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)

Position: -71
Score: 5.6
Sequence: AATTTTCAGATAATT
Locus tag: SP_1584
Name: codY
Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family
Locus tag: SP_1583
Name: pncA
Funciton: Nicotinamidase (EC 3.5.1.19)
codY
Nutrient limitation global transcriptional regulator CodY, CodY family
pncA
Nicotinamidase (EC 3.5.1.19)

Position: -94
Score: 5.5
Sequence: AATTTTTAGAAAATT
Locus tag: SP_1306
Name: gdhA
Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
gdhA
NADP-specific glutamate dehydrogenase (EC 1.4.1.4)

Position: -88
Score: 5.8
Sequence: AATTTTCTGAAAATT
Locus tag: SP_0856
Name: ilvE
Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
ilvE
Branched-chain amino acid aminotransferase (EC 2.6.1.42)

Position: -33
Score: 5.2
Sequence: ATTATTCTGAAAATT
Locus tag: SP_0159
Name: SMU.1109
Funciton: Predicted Mn2+/Fe2+ transporter, NRAMP family
SMU.1109
Predicted Mn2+/Fe2+ transporter, NRAMP family

Position: -55
Score: 5.2
Sequence: GATTTTCTGAAAATT
Locus tag: SP_1119
Name: gapN
Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
gapN
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)

Position: -55
Score: 4.7
Sequence: AATTGTCAGATAATA
Locus tag: SP_1578
Name: ubiE
Funciton: SAM-dependent methyltransferase
ubiE
SAM-dependent methyltransferase

Position: -57
Score: 5.4
Sequence: AATTTTCTGAAAAAT
Locus tag: SP_2066
Name: thrC
Funciton: Threonine synthase (EC 4.2.3.1)
thrC
Threonine synthase (EC 4.2.3.1)

Position: -93
Score: 5.3
Sequence: AAAATTCAGAAAATT
Locus tag: SP_0445
Name: ilvB
Funciton: Acetolactate synthase large subunit (EC 2.2.1.6)
Locus tag: SP_0446
Name: ilvN
Funciton: Acetolactate synthase small subunit (EC 2.2.1.6)
Locus tag: SP_0447
Name: ilvC
Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86)
Locus tag: SP_0448
Name: SP_0448
Funciton: Hypothetical protein
Locus tag: SP_0449
Name: SP_0449
Funciton: Hypothetical protein
Locus tag: SP_0450
Name: ilvA
Funciton: Threonine dehydratase (EC 4.3.1.19)
ilvB
Acetolactate synthase large subunit (EC 2.2.1.6)
ilvN
Acetolactate synthase small subunit (EC 2.2.1.6)
ilvC
Ketol-acid reductoisomerase (EC 1.1.1.86)
SP_0448
Hypothetical protein
SP_0449
Hypothetical protein
ilvA
Threonine dehydratase (EC 4.3.1.19)

Position: -112
Score: 5
Sequence: AAGATTCTGAAAATT
Locus tag: SP_1961
Name: rpoB
Funciton: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
Locus tag: SP_1960
Name: rpoC
Funciton: DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
rpoB
DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
rpoC
DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)

Position: -85
Score: 5.8
Sequence: AATTTTCTGAAAATT
Locus tag: SP_2126
Name: ilvD
Funciton: Dihydroxy-acid dehydratase (EC 4.2.1.9)
ilvD
Dihydroxy-acid dehydratase (EC 4.2.1.9)

Position: -80
Score: 5.2
Sequence: AATTGTCAGAAATTT
Locus tag: SP_1869
Name: fatD
Funciton: Iron-siderophore ABC transporter, permease protein 1
Locus tag: SP_1870
Name: fatC
Funciton: Iron-siderophore ABC transporter, permease protein 2
Locus tag: SP_1871
Name: fatA
Funciton: Iron-siderophore ABC transporter, ATP-binding protein
Locus tag: SP_1872
Name: fatB
Funciton: Iron-siderophore ABC transporter, substrate-binding protein
fatD
Iron-siderophore ABC transporter, permease protein 1
fatC
Iron-siderophore ABC transporter, permease protein 2
fatA
Iron-siderophore ABC transporter, ATP-binding protein
fatB
Iron-siderophore ABC transporter, substrate-binding protein

Position: -31
Score: 5.5
Sequence: AATTTTTAGAAAATT
Locus tag: SP_1013
Name: asd
Funciton: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
Locus tag: SP_1014
Name: dapA
Funciton: Dihydrodipicolinate synthase (EC 4.2.1.52)
asd
Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
dapA
Dihydrodipicolinate synthase (EC 4.2.1.52)

Position: -183
Score: 4.4
Sequence: TAATTTCTAATAATT
Locus tag: SP_0754
Name: acuB
Funciton: Acetoin utilization protein AcuB
acuB
Acetoin utilization protein AcuB

Position: -69
Score: 4.7
Sequence: AACTATCAGAATATT
Locus tag: SP_0141
Name: mutR
Funciton: Predicted transcriptional regulator, Xre family
mutR
Predicted transcriptional regulator, Xre family

Position: -56
Score: 5.2
Sequence: AATTTTCACAAAATT
Locus tag: SP_1361
Name: hom
Funciton: Homoserine dehydrogenase (EC 1.1.1.3)
Locus tag: SP_1360
Name: thrB
Funciton: Homoserine kinase (EC 2.7.1.39)
hom
Homoserine dehydrogenase (EC 1.1.1.3)
thrB
Homoserine kinase (EC 2.7.1.39)

Position: -41
Score: 5
Sequence: AAAATTTAGAAAATT
Locus tag: SP_0095
Name: ymdE
Funciton: Conserved hypothetical protein
ymdE
Conserved hypothetical protein

Position: -183
Score: 5.3
Sequence: AAATTTCAGAAATTT
Locus tag: SP_0711
Name: str1582
Funciton: Predicted amino acid ABC transporter, permease protein 1
Locus tag: SP_0710
Name: str1581
Funciton: Predicted amino acid ABC transporter, permease protein 2
Locus tag: SP_0709
Name: str1580
Funciton: Predicted amino acid ABC transporter, ATP-binding protein
str1582
Predicted amino acid ABC transporter, permease protein 1
str1581
Predicted amino acid ABC transporter, permease protein 2
str1580
Predicted amino acid ABC transporter, ATP-binding protein

Position: -60
Score: 5.6
Sequence: AATTTTCTGATAATT
Locus tag: SP_0749
Name: livK
Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
Locus tag: SP_0750
Name: livH
Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
Locus tag: SP_0751
Name: livM
Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
Locus tag: SP_0752
Name: livG
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
Locus tag: SP_0753
Name: livF
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
livK
Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
livH
Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
livM
Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
livG
Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
livF
Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD