Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CodY in Streptococcus gallolyticus UCN34

Properties
Regulator type: Transcription factor
TF locus tag: GALLO_1876
Regulator family: CodY
Regulation mode: repressor (activator)
Biological process: Amino acid metabolism
Effector: Guanosine triphosphate; Branched-chain amino acids
Regulog: CodY - Streptococcaceae
Statistics of regulated genes:
- Genes 60
- Operons 28
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 273 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -77
Score: 5.6
Sequence: AATTTTCAGATAATT
Locus tag: GALLO_1876
Name: codY
Funciton: Nutrient limitation global transcriptional regulator CodY, CodY family
Locus tag: GALLO_1875
Name: pncA
Funciton: Nicotinamidase (EC 3.5.1.19)
codY
Nutrient limitation global transcriptional regulator CodY, CodY family
pncA
Nicotinamidase (EC 3.5.1.19)

Position: -266
Score: 5
Sequence: AGTATTCAGAAAATT
Locus tag: GALLO_0758
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: GALLO_0759
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: GALLO_0760
Name: ygaE
Funciton: Predicted transmembrane protein
Locus tag: GALLO_0761
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: GALLO_0762
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
leuA
2-isopropylmalate synthase (EC 2.3.3.13)
leuB
3-isopropylmalate dehydrogenase (EC 1.1.1.85)
ygaE
Predicted transmembrane protein
leuC
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)

Position: -45
Score: 5.3
Sequence: AATTATCTGAATATT
Locus tag: GALLO_1124
Name: SMU.1109
Funciton: Predicted Mn2+/Fe2+ transporter, NRAMP family
SMU.1109
Predicted Mn2+/Fe2+ transporter, NRAMP family

Position: -87
Score: 5.3
Sequence: AATTTTCTGAATTTT
Locus tag: GALLO_0746
Name: gapN
Funciton: Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)
gapN
Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NADP) (EC 1.2.1.9)

Position: -215
Score: 4.6
Sequence: AAAAGTCAGAAAAAT
Locus tag: GALLO_0324
Name: oppA1
Funciton: Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
Locus tag: GALLO_0325
Name: oppB1
Funciton: Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
Locus tag: GALLO_0326
Name: oppC1
Funciton: Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
Locus tag: GALLO_0327
Name: oppD1
Funciton: Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
Locus tag: GALLO_0328
Name: oppF1
Funciton: Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)
oppA1
Oligopeptide ABC transporter, substrate-binding protein (TC 3.A.1.5.1)
oppB1
Oligopeptide ABC transporter, permease protein 1 (TC 3.A.1.5.1)
oppC1
Oligopeptide ABC transporter, permease protein 2 (TC 3.A.1.5.1)
oppD1
Oligopeptide ABC transporter, ATP-binding protein 1 (TC 3.A.1.5.1)
oppF1
Oligopeptide ABC transporter, ATP-binding protein 2 (TC 3.A.1.5.1)

Position: -51
Score: 5.3
Sequence: AAAATTCAGAAAATT
Locus tag: GALLO_1746
Name: serC
Funciton: Phosphoserine aminotransferase (EC 2.6.1.52)
Locus tag: GALLO_1745
Name: yesJ
Funciton: Acetyltransferase (EC 2.3.1.-), GNAT family
Locus tag: GALLO_1744
Name: serA
Funciton: D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)
serC
Phosphoserine aminotransferase (EC 2.6.1.52)
yesJ
Acetyltransferase (EC 2.3.1.-), GNAT family
serA
D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95)

Position: -59
Score: 5
Sequence: AATATTCTGAATAAT
Locus tag: GALLO_1991
Name: gltB
Funciton: Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
Locus tag: GALLO_1990
Name: gltD
Funciton: Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
gltB
Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
gltD
Glutamate synthase [NADPH] small chain (EC 1.4.1.13)

Position: -78
Score: 5.8
Sequence: AATTTTCAGAAAATT
Locus tag: GALLO_1293
Name: gdhA
Funciton: NADP-specific glutamate dehydrogenase (EC 1.4.1.4)
gdhA
NADP-specific glutamate dehydrogenase (EC 1.4.1.4)

Position: -84
Score: 5.3
Sequence: AATTTTCAGAATTTT
Locus tag: GALLO_0979
Name: ilvE
Funciton: Branched-chain amino acid aminotransferase (EC 2.6.1.42)
ilvE
Branched-chain amino acid aminotransferase (EC 2.6.1.42)

Position: -148
Score: 5
Sequence: AAAATTTAGAAAATT
Locus tag: GALLO_1749
Name: nrgA
Funciton: Ammonium transporter
Locus tag: GALLO_1748
Name: nrgB
Funciton: Nitrogen regulatory protein P-II
nrgA
Ammonium transporter
nrgB
Nitrogen regulatory protein P-II

Position: -61
Score: 5.6
Sequence: AATTTTCTGATAATT
Locus tag: GALLO_0042
Name: thrC
Funciton: Threonine synthase (EC 4.2.3.1)
thrC
Threonine synthase (EC 4.2.3.1)

Position: -42
Score: 5.2
Sequence: AATTTTTAGATAATT
Locus tag: GALLO_0305
Name: ilvB
Funciton: Acetolactate synthase large subunit (EC 2.2.1.6)
Locus tag: GALLO_0306
Name: ilvN
Funciton: Acetolactate synthase small subunit (EC 2.2.1.6)
Locus tag: GALLO_0307
Name: ilvC
Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86)
Locus tag: GALLO_0308
Name: ilvA
Funciton: Threonine dehydratase (EC 4.3.1.19)
ilvB
Acetolactate synthase large subunit (EC 2.2.1.6)
ilvN
Acetolactate synthase small subunit (EC 2.2.1.6)
ilvC
Ketol-acid reductoisomerase (EC 1.1.1.86)
ilvA
Threonine dehydratase (EC 4.3.1.19)

Position: -109
Score: 5.8
Sequence: AATTTTCAGAAAATT
Locus tag: GALLO_0871
Name: fatD
Funciton: Iron-siderophore ABC transporter, permease protein 1
Locus tag: GALLO_0872
Name: fatC
Funciton: Iron-siderophore ABC transporter, permease protein 2
Locus tag: GALLO_0873
Name: fatA
Funciton: Iron-siderophore ABC transporter, ATP-binding protein
Locus tag: GALLO_0874
Name: fatB
Funciton: Iron-siderophore ABC transporter, substrate-binding protein
fatD
Iron-siderophore ABC transporter, permease protein 1
fatC
Iron-siderophore ABC transporter, permease protein 2
fatA
Iron-siderophore ABC transporter, ATP-binding protein
fatB
Iron-siderophore ABC transporter, substrate-binding protein

Position: -125
Score: 4.7
Sequence: AAATGTCAGAATTTT
Locus tag: GALLO_0478
Name: pepC
Funciton: Aminopeptidase C (EC 3.4.22.40)
pepC
Aminopeptidase C (EC 3.4.22.40)

Position: -206
Score: 4.6
Sequence: AATATTTTTAAAATT
Locus tag: GALLO_0890
Name: SMU.63c
Funciton: Conserved hypothetical secreted protein
SMU.63c
Conserved hypothetical secreted protein

Position: -118
Score: 4.8
Sequence: ATTTTTCTGTAAATT
Locus tag: GALLO_1241
Name: hom
Funciton: Homoserine dehydrogenase (EC 1.1.1.3)
Locus tag: GALLO_1240
Name: thrB
Funciton: Homoserine kinase (EC 2.7.1.39)
hom
Homoserine dehydrogenase (EC 1.1.1.3)
thrB
Homoserine kinase (EC 2.7.1.39)

Position: -100
Score: 5
Sequence: AATTTTCAGAAAAAA
Locus tag: GALLO_0748
Name: scpC
Funciton: Serine endopeptidase ScpC (EC 3.4.21.-)
scpC
Serine endopeptidase ScpC (EC 3.4.21.-)

Position: -220
Score: 5.1
Sequence: AATTTTCTGATTTTT
Locus tag: GALLO_1516
Name: pepF
Funciton: Oligoendopeptidase F
pepF
Oligoendopeptidase F

Position: -114
Score: 5.1
Sequence: AATTTTCTGAATATA
Locus tag: GALLO_1555
Name: gluQ
Funciton: Glutamate ABC transporter, ATP-binding protein
Locus tag: GALLO_1556
Name: gluH
Funciton: Glutamate ABC transporter, substrate-binding protein
Locus tag: GALLO_1557
Name: gluM
Funciton: Glutamate ABC transporter, permease protein 1
Locus tag: GALLO_1558
Name: gluP
Funciton: Glutamate ABC transporter, permease protein 2
gluQ
Glutamate ABC transporter, ATP-binding protein
gluH
Glutamate ABC transporter, substrate-binding protein
gluM
Glutamate ABC transporter, permease protein 1
gluP
Glutamate ABC transporter, permease protein 2

Position: -132
Score: 5.1
Sequence: AAAAATCAGAAAATT
Locus tag: GALLO_1515
Name: ppc
Funciton: Phosphoenolpyruvate carboxylase (EC 4.1.1.31)
ppc
Phosphoenolpyruvate carboxylase (EC 4.1.1.31)

Position: -38
Score: 4.7
Sequence: AATTTTCAGACTATA
Locus tag: GALLO_1993
Name: glnR
Funciton: Nitrogen metabolism transcriptional regulator GlnR, MerR family
Locus tag: GALLO_1992
Name: glnA
Funciton: Glutamine synthetase type I (EC 6.3.1.2)
glnR
Nitrogen metabolism transcriptional regulator GlnR, MerR family
glnA
Glutamine synthetase type I (EC 6.3.1.2)

Position: -153
Score: 4.7
Sequence: TATTTTCTGACTATT
Locus tag: GALLO_0638
Name: dtpT
Funciton: Di- and tripeptide permease DtpT
dtpT
Di- and tripeptide permease DtpT

Position: -52
Score: 5.3
Sequence: AATTTTCAGAATTTT
Locus tag: GALLO_0331
Name: thrA
Funciton: Aspartokinase (EC 2.7.2.4)
thrA
Aspartokinase (EC 2.7.2.4)

Position: -144
Score: 4.8
Sequence: AATTTTCAAAAAAGT
Locus tag: GALLO_0534
Name: asnA
Funciton: Aspartate--ammonia ligase (EC 6.3.1.1)
asnA
Aspartate--ammonia ligase (EC 6.3.1.1)

Position: -56
Score: 4.6
Sequence: AATTTTCAGTTATTT
Locus tag: GALLO_1433
Name: aroA
Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
Locus tag: GALLO_1432
Name: aroK
Funciton: Shikimate kinase I (EC 2.7.1.71)
Locus tag: GALLO_1431
Name: pheA
Funciton: Prephenate dehydratase (EC 4.2.1.51)
aroA
5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
aroK
Shikimate kinase I (EC 2.7.1.71)
pheA
Prephenate dehydratase (EC 4.2.1.51)

Position: -66
Score: 5.6
Sequence: AATTTTCTGATAATT
Locus tag: GALLO_1760
Name: livK
Funciton: Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
Locus tag: GALLO_1759
Name: livH
Funciton: Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
Locus tag: GALLO_1758
Name: livM
Funciton: Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
Locus tag: GALLO_1757
Name: livG
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
Locus tag: GALLO_1756
Name: livF
Funciton: Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)
livK
Branched-chain amino acids ABC transporter, substrate-binding protein (TC 3.A.1.4.1)
livH
Branched-chain amino acids ABC transporter, permease protein 1 (TC 3.A.1.4.1)
livM
Branched-chain amino acids ABC transporter, permease protein 2 (TC 3.A.1.4.1)
livG
Branched-chain amino acids ABC transporter, ATP-binding protein 1 (TC 3.A.1.4.1)
livF
Branched-chain amino acids ABC transporter, ATP-binding protein 2 (TC 3.A.1.4.1)

Position: -52
Score: 5.1
Sequence: ATTTTTTAGAAAATT
Locus tag: GALLO_1113
Name: asd
Funciton: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
Locus tag: GALLO_1112
Name: dapA
Funciton: Dihydrodipicolinate synthase (EC 4.2.1.52)
asd
Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
dapA
Dihydrodipicolinate synthase (EC 4.2.1.52)

Position: -165
Score: 4.6
Sequence: AAGATTCTAAAAATT
Locus tag: GALLO_0084
Name: rpoB
Funciton: DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
Locus tag: GALLO_0085
Name: rpoC
Funciton: DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
rpoB
DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)
rpoC
DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD