Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of NanR in Streptococcus pneumoniae TIGR4

Properties
Regulator type: Transcription factor
TF locus tag: SP_1331, SP_1674
Regulator family: RpiR
Regulation mode: repressor
Biological process: Sialic acid utilization
Effector: N-acetylneuraminic acid
Regulog: NanR - Streptococcaceae
Statistics of regulated genes:
- Genes 15
- Operons 3
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 16 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -94
Score: 5.7
Sequence: TTGGAAACTAGTTTCTAA
Locus tag: SP_1331
Name: nanR
Funciton: Sialic acid utilization transcriptional regulator NanR, RpiR family
Locus tag: SP_1330
Name: nanE2
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: SP_1329
Name: nanA2
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: SP_1328
Name: nanT
Funciton: Predicted sialic acid transporter
Locus tag: SP_1327
Name: SP_1327
Funciton: Hypothetical protein
Locus tag: SP_1326
Name: neuA
Funciton: Sialidase (EC 3.2.1.18)
Locus tag: SP_1325
Name: SP_1325
Funciton: Predcted oxidoreductase, GFO/IDH/MOCA family
Locus tag: SP_1324
Name: nanK2
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
nanR
Sialic acid utilization transcriptional regulator NanR, RpiR family
nanE2
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanA2
N-acetylneuraminate lyase (EC 4.1.3.3)
nanT
Predicted sialic acid transporter
SP_1327
Hypothetical protein
neuA
Sialidase (EC 3.2.1.18)
SP_1325
Predcted oxidoreductase, GFO/IDH/MOCA family
nanK2
N-acetylmannosamine kinase (EC 2.7.1.60)

Position: -158
Score: 6.4
Sequence: TCTGAAACTACTTTCAAA
Locus tag: SP_1676
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: SP_1675
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
nanA
N-acetylneuraminate lyase (EC 4.1.3.3)
nanK
N-acetylmannosamine kinase (EC 2.7.1.60)

Position: -136
Score: 5.9
Sequence: TCTGAAAGTACTTTTAGA
Locus tag: SP_1685
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: SP_1684
Name: nanP
Funciton: N-acetylglucosamine-specific PTS system, EIIABC component (EC 2.7.1.69)
Locus tag: SP_1683
Name: nanU
Funciton: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein
Locus tag: SP_1682
Name: nanV
Funciton: Predicted N-acetylneuraminate ABC transporter, permease protein 1
Locus tag: SP_1681
Name: nanW
Funciton: Predicted N-acetylneuraminate ABC transporter, permease protein 2
nanE
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanP
N-acetylglucosamine-specific PTS system, EIIABC component (EC 2.7.1.69)
nanU
Predicted N-acetylneuraminate ABC transporter, substrat-binding protein
nanV
Predicted N-acetylneuraminate ABC transporter, permease protein 1
nanW
Predicted N-acetylneuraminate ABC transporter, permease protein 2
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