Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of NanR in Streptococcus mitis B6

Properties
Regulator type: Transcription factor
TF locus tag: smi_0612, smi_0792
Regulator family: RpiR
Regulation mode: repressor
Biological process: Sialic acid utilization
Effector: N-acetylneuraminic acid
Regulog: NanR - Streptococcaceae
Statistics of regulated genes:
- Genes 15
- Operons 3
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 16 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -96
Score: 5.7
Sequence: TTGGAAACTAGTTTCTAA
Locus tag: smi_0792
Name: nanR
Funciton: Sialic acid utilization transcriptional regulator NanR, RpiR family
Locus tag: smi_0793
Name: nanE2
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: smi_0794
Name: nanA2
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: smi_0795
Name: nanT
Funciton: Predicted sialic acid transporter
Locus tag: smi_0796
Name: SP_1327
Funciton: Hypothetical protein
Locus tag: smi_0797
Name: SP_1325
Funciton: Predcted oxidoreductase, GFO/IDH/MOCA family
Locus tag: smi_0798
Name: nanK2
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
nanR
Sialic acid utilization transcriptional regulator NanR, RpiR family
nanE2
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanA2
N-acetylneuraminate lyase (EC 4.1.3.3)
nanT
Predicted sialic acid transporter
SP_1327
Hypothetical protein
SP_1325
Predcted oxidoreductase, GFO/IDH/MOCA family
nanK2
N-acetylmannosamine kinase (EC 2.7.1.60)

Position: -160
Score: 6.2
Sequence: TCTGAAACTACTTTCAAG
Locus tag: smi_0608
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: smi_0609
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
nanA
N-acetylneuraminate lyase (EC 4.1.3.3)
nanK
N-acetylmannosamine kinase (EC 2.7.1.60)

Position: -135
Score: 6.3
Sequence: TCTGAAACTACTTTCAGA
Locus tag: smi_0602
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: smi_0603
Name: nanU
Funciton: Predicted N-acetylneuraminate ABC transporter, substrat-binding protein
Locus tag: smi_0604
Name: nanV
Funciton: Predicted N-acetylneuraminate ABC transporter, permease protein 1
Locus tag: smi_0605
Name: nanW
Funciton: Predicted N-acetylneuraminate ABC transporter, permease protein 2
Locus tag: smi_0606
Name: yjgK
Funciton: Conserved hypothetical protein
Locus tag: smi_0607
Name: SDEG_1954
Funciton: Predicted membrane protein
nanE
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanU
Predicted N-acetylneuraminate ABC transporter, substrat-binding protein
nanV
Predicted N-acetylneuraminate ABC transporter, permease protein 1
nanW
Predicted N-acetylneuraminate ABC transporter, permease protein 2
yjgK
Conserved hypothetical protein
SDEG_1954
Predicted membrane protein
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