Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Streptococcus pyogenes M1 GAS

Properties
Regulator type: Transcription factor
TF locus tag: SPy0268
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Streptococcaceae
Statistics of regulated genes:
- Genes 11
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 100 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -78
Score: 4.7
Sequence: AAAAACGAACCTT
Locus tag: SPy0024
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: SPy0025
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: SPy0026
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: SPy0027
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: SPy0028
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)

Position: -205
Score: 4.7
Sequence: AAAACCGAACTTT
Locus tag: SPy1135
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -55
Score: 4.9
Sequence: AAAAGCGAACGTT
Locus tag: SPy0032
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Locus tag: SPy0033
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: SPy0034
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

Position: -93
Score: 5.1
Sequence: AAAAACGAACAAT
Locus tag: SPy1213
Name: fhs
Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
fhs
Formate--tetrahydrofolate ligase (EC 6.3.4.3)

Position: -102
Score: 5
Sequence: AATACCGAACAAT
Locus tag: SPy1736
Name: pbuO
Funciton: Guanine/hypoxanthine permease
pbuO
Guanine/hypoxanthine permease
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