Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Streptococcus mutans UA159

Properties
Regulator type: Transcription factor
TF locus tag: SMU.356
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Streptococcaceae
Statistics of regulated genes:
- Genes 14
- Operons 3
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 100 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -109
Score: 4.8
Sequence: AAATGCGAACGAT
Position: -16
Score: 4.7
Sequence: AAAGGCGAACAAT
Locus tag: SMU.29
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: SMU.30
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: SMU.31
Name: null
Funciton: DNA alkylation repair enzyme
Locus tag: SMU.32
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: SMU.33
Name: SMU.33
Funciton: Hypothetical protein
Locus tag: SMU.34
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: SMU.35
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: SMU.36
Name: SMU.36
Funciton: Hypothetical protein
Locus tag: SMU.37
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
DNA alkylation repair enzyme
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
SMU.33
Hypothetical protein
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
SMU.36
Hypothetical protein
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)

Position: -90
Score: 5.1
Sequence: AAATCCGAACATT
Locus tag: SMU.1073
Name: fhs
Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
fhs
Formate--tetrahydrofolate ligase (EC 6.3.4.3)

Position: -122
Score: 3.5
Sequence: ACTCCCGAACAAA
Locus tag: SMU.48
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Locus tag: SMU.49
Name: carB2
Funciton: Carbamoyl-phosphate synthase large subunit (EC 6.3.5.5) paralog
Locus tag: SMU.50
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: SMU.51
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
carB2
Carbamoyl-phosphate synthase large subunit (EC 6.3.5.5) paralog
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
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