Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Streptococcus mitis B6

Properties
Regulator type: Transcription factor
TF locus tag: smi_0302
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Streptococcaceae
Statistics of regulated genes:
- Genes 13
- Operons 5
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 100 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -216
Score: 4.3
Sequence: ATTTCCGAACAAA
Locus tag: smi_0022
Name: purA
Funciton: Adenylosuccinate synthetase (EC 6.3.4.4)
purA
Adenylosuccinate synthetase (EC 6.3.4.4)

Position: -141
Score: 4.9
Sequence: AAATCCGAACGAT
Locus tag: smi_1212
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -56
Score: 4.6
Sequence: TAAAACGAACGTT
Locus tag: smi_0073
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Locus tag: smi_0074
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: smi_0075
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

Position: -90
Score: 4.2
Sequence: TTTTACGAACGTT
Locus tag: smi_1192
Name: fhs
Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
fhs
Formate--tetrahydrofolate ligase (EC 6.3.4.3)

Position: 155
Score: 4.3
Sequence: AAAGGCGAACTTT
Locus tag: smi_0066
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: smi_0067
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: smi_0068
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
Locus tag: smi_0069
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: smi_0070
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
Locus tag: smi_0071
Name: smi_0071
Funciton: Acetyltransferase, putative
Locus tag: smi_0072
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
smi_0071
Acetyltransferase, putative
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
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