Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PurR in Lactococcus lactis subsp. lactis Il1403

Properties
Regulator type: Transcription factor
TF locus tag: L134453
Regulator family: PurR
Regulation mode: repressor
Biological process: Purine metabolism
Effector: 5-phosphoribosyl 1-pyrophosphate
Regulog: PurR - Streptococcaceae
Statistics of regulated genes:
- Genes 22
- Operons 16
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 100 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -131
Score: 4.8
Sequence: ATTTCCGAACAAT
Locus tag: L159505
Name: fhs
Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
fhs
Formate--tetrahydrofolate ligase (EC 6.3.4.3)

Position: -124
Score: 5.2
Sequence: AAAAACGAACATT
Locus tag: L0368
Name: fusA
Funciton: Translation elongation factor G
fusA
Translation elongation factor G

Position: -242
Score: 4.6
Sequence: ATTTCCGAACGAT
Locus tag: L12179
Name: purA
Funciton: Adenylosuccinate synthetase (EC 6.3.4.4)
purA
Adenylosuccinate synthetase (EC 6.3.4.4)

Position: -53
Score: 4.9
Sequence: AATTACGAACAAT
Locus tag: L76582
Name: folD
Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
folD
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)

Position: -203
Score: 4.8
Sequence: ATTTCCGAACATT
Locus tag: L0082
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)

Position: -170
Score: 4.8
Sequence: ATTTCCGAACAAT
Locus tag: L158710
Name: purH
Funciton: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
purH
IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)

Position: -124
Score: 4.8
Sequence: ATTTCCGAACATT
Locus tag: L61620
Name: bmpA
Funciton: Predicted nucleoside ABC transporter, substrate-binding protein
bmpA
Predicted nucleoside ABC transporter, substrate-binding protein

Position: -115
Score: 4.6
Sequence: ATTTCCGAACGAT
Locus tag: L165202
Name: purM
Funciton: Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
Locus tag: L164626
Name: purN
Funciton: Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)
purM
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1)
purN
Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2)

Position: -132
Score: 4.8
Sequence: ATTTCCGAACATT
Position: -115
Score: 5.1
Sequence: AAAACCGAACAAT
Locus tag: L177350
Name: purC
Funciton: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Locus tag: L177031
Name: purS
Funciton: Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
Locus tag: L176360
Name: purQ
Funciton: Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
Locus tag: L173921
Name: purL
Funciton: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
purS
Phosphoribosylformylglycinamidine synthase, PurS subunit (EC 6.3.5.3)
purQ
Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)

Position: -224
Score: 5
Sequence: AATACCGAACAAT
Locus tag: L153005
Name: purD
Funciton: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Locus tag: L152487
Name: purE
Funciton: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Locus tag: L151330
Name: purK
Funciton: Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)
purD
Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

Position: -158
Score: 4.4
Sequence: CAAAACGAACAAT
Locus tag: L62663
Name: ppa
Funciton: Manganese-dependent inorganic pyrophosphatase (EC 3.6.1.1)
ppa
Manganese-dependent inorganic pyrophosphatase (EC 3.6.1.1)

Position: -227
Score: 3.9
Sequence: ATTTCCGAATGAT
Locus tag: L158186
Name: guaC
Funciton: GMP reductase (EC 1.7.1.7)
guaC
GMP reductase (EC 1.7.1.7)

Position: -113
Score: 4.3
Sequence: TTTTCCGAACAAT
Position: -61
Score: 4.1
Sequence: ATTTCCAAACAAT
Locus tag: L171350
Name: purF
Funciton: Amidophosphoribosyltransferase (EC 2.4.2.14)
purF
Amidophosphoribosyltransferase (EC 2.4.2.14)

Position: -184
Score: 4.9
Sequence: ATTACCGAACAAT
Locus tag: L171588
Name: pbuO
Funciton: Guanine/hypoxanthine permease
pbuO
Guanine/hypoxanthine permease

Position: -110
Score: 4.7
Sequence: ATTTCCGAACGTT
Locus tag: L160442
Name: hprT
Funciton: Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)
hprT
Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8)

Position: 6
Score: 4.4
Sequence: AGAAACGAACGTT
Locus tag: L134453
Name: purR
Funciton: Purine metabolism transcriptional regulator PurR, PurR family
purR
Purine metabolism transcriptional regulator PurR, PurR family
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