Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of PerR in Streptococcus pyogenes M1 GAS

Properties
Regulator type: Transcription factor
TF locus tag: SPy0187
Regulator family: FUR
Regulation mode: repressor
Biological process: Iron homeostasis; Manganese homeostasis; Oxidative stress response
Effector: Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide
Regulog: PerR - Streptococcaceae
Statistics of regulated genes:
- Genes 12
- Operons 6
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 75 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -157
Score: 4.7
Sequence: CGATAATGATTCTAA
Locus tag: SPy1531
Name: mgrA
Funciton: Non-specific DNA-binding protein / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)
mgrA
Non-specific DNA-binding protein / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1)

Position: -124
Score: 5.6
Sequence: TTATAATGATTATTA
Locus tag: SPy0453
Name: mntA
Funciton: Manganese ABC transporter, substrate binding protein
Locus tag: SPy0454
Name: mntC
Funciton: Manganese ABC transporter, ATP-binding protein
Locus tag: SPy0456
Name: mntB
Funciton: Manganese ABC transporter, permease protein
mntA
Manganese ABC transporter, substrate binding protein
mntC
Manganese ABC transporter, ATP-binding protein
mntB
Manganese ABC transporter, permease protein

Position: -36
Score: 5.6
Sequence: TAATAATCATTATAA
Locus tag: SPy0450
Name: mntR
Funciton: Manganese homeostasis transcriptional regulator MntR, DtxR family
mntR
Manganese homeostasis transcriptional regulator MntR, DtxR family

Position: -228
Score: 4.6
Sequence: TTAGAATGATTATCG
Position: -206
Score: 5.2
Sequence: TTTTAATCATTCTAA
Locus tag: SPy0386
Name: fhuA
Funciton: Ferrichrome ABC transporter, ATP-binding protein
Locus tag: SPy0385
Name: fhuD
Funciton: Ferrichrome ABC transporter, substrate-binding protein
Locus tag: SPy0384
Name: fhuB
Funciton: Ferrichrome ABC transporter, permease protein 1
Locus tag: SPy0383
Name: fhuG
Funciton: Ferrichrome ABC transporter, permease protein 2
fhuA
Ferrichrome ABC transporter, ATP-binding protein
fhuD
Ferrichrome ABC transporter, substrate-binding protein
fhuB
Ferrichrome ABC transporter, permease protein 1
fhuG
Ferrichrome ABC transporter, permease protein 2

Position: -154
Score: 5.7
Sequence: TTAGAATCATTTTAA
Locus tag: SPy2079
Name: ahpC
Funciton: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
Locus tag: SPy2080
Name: ahpF
Funciton: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
ahpC
Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
ahpF
Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)

Position: -97
Score: 5.4
Sequence: TTAGAATGTTTCTAA
Position: -64
Score: 5.8
Sequence: TTAGAATTATTATAA
Locus tag: SPy1434
Name: pmtA
Funciton: Predicted cation transporting ATPase
pmtA
Predicted cation transporting ATPase
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD