Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of CcpA in Lactococcus lactis subsp. lactis Il1403

Properties
Regulator type: Transcription factor
TF locus tag: L0143
Regulator family: LacI
Regulation mode:
Biological process: Global catabolite repression
Effector: Fructose-1,6-bisphosphate; HPr, phosphocarrier protein
Regulog: CcpA - Streptococcaceae
Statistics of regulated genes:
- Genes 54
- Operons 31
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 968 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -123
Score: 3.8
Sequence: ATGTGAGCGCTTTACT
Locus tag: L54021
Name: fbp
Funciton: Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)
fbp
Fructose-1,6-bisphosphatase, Bacillus type (EC 3.1.3.11)

Position: -173
Score: 4.1
Sequence: ATGAAAACCATTTTTA
Position: -137
Score: 4.4
Sequence: CTGTAAACCTTTTCAA
Locus tag: L96847
Name: pepQ
Funciton: Xaa-Pro dipeptidase (EC 3.4.13.9)
pepQ
Xaa-Pro dipeptidase (EC 3.4.13.9)

Position: -51
Score: 4.5
Sequence: TTGTAAACGATTCCAA
Locus tag: L0329
Name: arcA
Funciton: Arginine deiminase (EC 3.5.3.6)
Locus tag: L0109
Name: arcB
Funciton: Ornithine carbamoyltransferase (EC 2.1.3.3)
arcA
Arginine deiminase (EC 3.5.3.6)
arcB
Ornithine carbamoyltransferase (EC 2.1.3.3)

Position: -184
Score: 4.2
Sequence: TAGAAAACCCTTGCAA
Position: -143
Score: 4.4
Sequence: ATGAAAACGTTTCATA
Locus tag: L0002
Name: pfk
Funciton: 6-phosphofructokinase (EC 2.7.1.11)
Locus tag: L0003
Name: pyk
Funciton: Pyruvate kinase (EC 2.7.1.40)
pfk
6-phosphofructokinase (EC 2.7.1.11)
pyk
Pyruvate kinase (EC 2.7.1.40)

Position: -62
Score: 4.4
Sequence: ATGAAAACCGTTTCTA
Locus tag: L0043
Name: tkt
Funciton: Transketolase (EC 2.2.1.1)
tkt
Transketolase (EC 2.2.1.1)

Position: -87
Score: 4.3
Sequence: ATGAAAACATTTGCAA
Locus tag: L1762179
Name: manL
Funciton: PTS system, mannose-specific IIAB components
Locus tag: L146623
Name: manM
Funciton: PTS system, mannose-specific IIC component (EC 2.7.1.69)
Locus tag: L147466
Name: manN
Funciton: PTS system, mannose-specific IID component (EC 2.7.1.69)
Locus tag: L148513
Name: manO
Funciton: Putative regulator of the mannose operon, ManO
manL
PTS system, mannose-specific IIAB components
manM
PTS system, mannose-specific IIC component (EC 2.7.1.69)
manN
PTS system, mannose-specific IID component (EC 2.7.1.69)
manO
Putative regulator of the mannose operon, ManO

Position: -30
Score: 4.3
Sequence: AATAAAACGCATACAT
Locus tag: L0224
Name: ackA
Funciton: Acetate kinase (EC 2.7.2.1)
ackA
Acetate kinase (EC 2.7.2.1)

Position: -129
Score: 4.5
Sequence: TTGAAAAGGTTTTTAT
Locus tag: L73818
Name: ackA
Funciton: Acetate kinase (EC 2.7.2.1)
ackA
Acetate kinase (EC 2.7.2.1)

Position: -106
Score: 4.5
Sequence: ATAAAAACGATTTCAG
Locus tag: L47971
Name: fruR2
Funciton: Predicted fructose utilization transcriptional regulator FruR2, RpiR family
fruR2
Predicted fructose utilization transcriptional regulator FruR2, RpiR family

Position: -88
Score: 4.4
Sequence: ATGTAAAAGCTTACAA
Locus tag: L33416
Name: mtlD
Funciton: Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)
mtlD
Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17)

Position: -68
Score: 4.1
Sequence: TTTAATACGCTTACAG
Locus tag: L66222
Name: coaA
Funciton: Pantothenate kinase (EC 2.7.1.33)
coaA
Pantothenate kinase (EC 2.7.1.33)

Position: -117
Score: 4.1
Sequence: ATAAAAGGGCTTACAG
Locus tag: L0011
Name: gpmA
Funciton: 2,3-bisphosphoglycerate-dependent phosphoglycerate (EC 5.4.2.1)
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate (EC 5.4.2.1)

Position: -95
Score: 4.2
Sequence: ATGTGAACGCTTAAAA
Locus tag: L108994
Name: udk
Funciton: Uridine kinase (EC 2.7.1.48) [C1]
udk
Uridine kinase (EC 2.7.1.48) [C1]

Position: -95
Score: 4.4
Sequence: TAGAAAACGCTTCAAA
Position: -73
Score: 4.2
Sequence: ATGAGATCGCTATCAA
Locus tag: L121426
Name: ascB
Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86)
ascB
6-phospho-beta-glucosidase (EC 3.2.1.86)

Position: -100
Score: 4.4
Sequence: AATAAAGCGGTTACTT
Locus tag: L0009
Name: fbaA
Funciton: Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
fbaA
Fructose-bisphosphate aldolase class II (EC 4.1.2.13)

Position: -29
Score: 4.3
Sequence: ATAAATACGCTTTCAG
Locus tag: L195318
Name: fdhC
Funciton: Predicted formate transporter
fdhC
Predicted formate transporter

Position: -93
Score: 4.4
Sequence: TTGAAAAGGTTTACAG
Position: -57
Score: 4.1
Sequence: TAAAAATGGTTTTCAT
Locus tag: L0143
Name: ccpA
Funciton: Carbon catabolism global transcriptional regulator CcpA, LacI family
ccpA
Carbon catabolism global transcriptional regulator CcpA, LacI family

Position: -32
Score: 4.7
Sequence: AATAAACCGTTTTCAT
Locus tag: L128695
Name: malE
Funciton: Maltose/maltodextrin ABC transporter, substrate-binding protein
Locus tag: L128696
Name: malF
Funciton: Maltose/maltodextrin ABC transporter, permease protein 1
Locus tag: L128697
Name: malG
Funciton: Maltose/maltodextrin ABC transporter, permease protein 2
malE
Maltose/maltodextrin ABC transporter, substrate-binding protein
malF
Maltose/maltodextrin ABC transporter, permease protein 1
malG
Maltose/maltodextrin ABC transporter, permease protein 2

Position: -133
Score: 4.4
Sequence: ATGAAAGCTGTTTCAT
Locus tag: L32389
Name: raiA
Funciton: Ribosome-associated protein Y
raiA
Ribosome-associated protein Y

Position: -64
Score: 4.3
Sequence: CTGAAACCGCTTTTTT
Locus tag: L11851
Name: ywcC
Funciton: 6-phosphogluconolactonase (EC 3.1.1.31)
ywcC
6-phosphogluconolactonase (EC 3.1.1.31)

Position: -43
Score: 5.1
Sequence: AAGAAAGCGTTTACAA
Locus tag: L55758
Name: adhB1
Funciton: Alcohol dehydrogenase (EC 1.1.1.1)
adhB1
Alcohol dehydrogenase (EC 1.1.1.1)

Position: -64
Score: 4.5
Sequence: ATGAAAACGGATACAA
Locus tag: L0145
Name: rbsR
Funciton: Ribose utilization transcriptional regulator, LacI family
Locus tag: L86157
Name: rbsK
Funciton: Ribokinase (EC 2.7.1.15)
Locus tag: L85737
Name: rbsD
Funciton: Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
Locus tag: L84240
Name: rbsA
Funciton: Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
Locus tag: L83296
Name: rbsC
Funciton: Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)
Locus tag: L82310
Name: rbsB
Funciton: Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)
rbsR
Ribose utilization transcriptional regulator, LacI family
rbsK
Ribokinase (EC 2.7.1.15)
rbsD
Ribose ABC transport system, high affinity permease RbsD (TC 3.A.1.2.1)
rbsA
Ribose ABC transport system, ATP-binding protein RbsA (TC 3.A.1.2.1)
rbsC
Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)
rbsB
Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)

Position: -156
Score: 5.1
Sequence: ATGAAAACGTTTTAAA
Locus tag: L57408
Name: pfl
Funciton: Pyruvate formate-lyase (EC 2.3.1.54)
pfl
Pyruvate formate-lyase (EC 2.3.1.54)

Position: -148
Score: 4.7
Sequence: AAATAAGCGCTTACAT
Locus tag: L0012
Name: pgi
Funciton: Glucose-6-phosphate isomerase (EC 5.3.1.9)
pgi
Glucose-6-phosphate isomerase (EC 5.3.1.9)

Position: -56
Score: 5.1
Sequence: AAGAAAACGTTTTCTT
Locus tag: L93919
Name: malQ
Funciton: 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)
Locus tag: L94405
Name: malQ
Funciton: 4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)
Locus tag: L95975
Name: glgC
Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: L97131
Name: glgD
Funciton: Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
Locus tag: L98347
Name: glgA
Funciton: Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)
malQ
4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)
malQ
4-alpha-glucanotransferase (amylomaltase) (EC 2.4.1.25)
glgC
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
glgD
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
glgA
Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)

Position: -162
Score: 4.5
Sequence: ATGTAAACGATTTATA
Locus tag: L91456
Name: aat
Funciton: Aspartate aminotransferase (EC 2.6.1.1)
aat
Aspartate aminotransferase (EC 2.6.1.1)

Position: -187
Score: 4.5
Sequence: TTGAAAACGCAATCAA
Position: -96
Score: 4.5
Sequence: AATAAAACGGTTACAA
Locus tag: L0154
Name: licT
Funciton: Beta-glucoside bgl operon transcriptional antiterminator, BglG family
Locus tag: L90678
Name: bglP
Funciton: Beta-glucoside-specific PTS system, IIBCA component (EC 2.7.1.69)
Locus tag: L89194
Name: bglH
Funciton: 6-phospho-beta-glucosidase (EC 3.2.1.86)
licT
Beta-glucoside bgl operon transcriptional antiterminator, BglG family
bglP
Beta-glucoside-specific PTS system, IIBCA component (EC 2.7.1.69)
bglH
6-phospho-beta-glucosidase (EC 3.2.1.86)

Position: -135
Score: 4.2
Sequence: CTTCAAACGCTTACAA
Locus tag: L11729a
Name: atpE
Funciton: ATP synthase C chain (EC 3.6.3.14)
atpE
ATP synthase C chain (EC 3.6.3.14)

Position: -25
Score: 4.2
Sequence: TTGTAAACGAATTCAG
Locus tag: L0031
Name: fruR
Funciton: Fructose utilization transcriptional regulator FruR, DeoR family
Locus tag: L0032
Name: fruB
Funciton: 1-phosphofructokinase (EC 2.7.1.56)
Locus tag: L185031
Name: fruA
Funciton: Fructose-specific PTS system, IIABC component (EC 2.7.1.69)
fruR
Fructose utilization transcriptional regulator FruR, DeoR family
fruB
1-phosphofructokinase (EC 2.7.1.56)
fruA
Fructose-specific PTS system, IIABC component (EC 2.7.1.69)

Position: -129
Score: 4.9
Sequence: AAGAAAACGCTTTAAA
Locus tag: L117145
Name: butB
Funciton: 2,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific (EC 1.1.1.4)
Locus tag: L118271
Name: butA
Funciton: 2,3-butanediol dehydrogenase, S-alcohol forming, (R)-acetoin-specific (EC 1.1.1.4) / Acetoin (diacetyl) reductase (EC 1.1.1.5)
butB
2,3-butanediol dehydrogenase, R-alcohol forming, (R)- and (S)-acetoin-specific (EC 1.1.1.4)
butA
2,3-butanediol dehydrogenase, S-alcohol forming, (R)-acetoin-specific (EC 1.1.1.4) / Acetoin (diacetyl) reductase (EC 1.1.1.5)

Position: -62
Score: 4.3
Sequence: AAGAAAGCGCAAACAT
Locus tag: L129753
Name: msmX
Funciton: Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
Locus tag: L128777
Name: msmY
Funciton: Multiple sugar ABC transporter, membrane-spanning permease protein MsmG
Locus tag: L127223
Name: msmZ
Funciton: Multiple sugar ABC transporter, substrate-binding protein
msmX
Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
msmY
Multiple sugar ABC transporter, membrane-spanning permease protein MsmG
msmZ
Multiple sugar ABC transporter, substrate-binding protein
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