Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of TPP in Streptococcus pneumoniae TIGR4

Properties
Regulator type: RNA regulatory element
Name: TPP
RFAM: RF00059
Regulation mode:
Biological process: Thiamine biosynthesis
Effector: Thiamine pyrophosphate
Regulog: TPP - Streptococcaceae
Under regulation:
- Genes 15
- Operons 4
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -183
Score: 59
Sequence: AAACAACCACTAGGG...
Locus tag: SP_0726
Name: thiD
Funciton: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
thiD
Phosphomethylpyrimidine kinase (EC 2.7.4.7)

Position: -174
Score: 47.8
Sequence: ACATATAATATATGG...
Locus tag: SP_2199
Name: COG0011
Funciton: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family
Locus tag: SP_2198
Name: thiX
Funciton: Thiamin ABC transporter, transmembrane component
Locus tag: SP_2197
Name: thiY
Funciton: Thiamin ABC transporter, substrate-binding component
Locus tag: SP_2196
Name: thiZ
Funciton: Thiamin ABC transporter, ATPase component
COG0011
Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family
thiX
Thiamin ABC transporter, transmembrane component
thiY
Thiamin ABC transporter, substrate-binding component
thiZ
Thiamin ABC transporter, ATPase component

Position: -349
Score: 67.7
Sequence: AAAGACATTTGGGGT...
Locus tag: SP_0719
Name: ykoE
Funciton: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
Locus tag: SP_0720
Name: ykoD
Funciton: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
Locus tag: SP_0721
Name: ykoC
Funciton: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
Locus tag: SP_0722
Name: tenA
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: SP_0723
Name: thiW
Funciton: Substrate-specific component ThiW of predicted thiazole ECF transporter
Locus tag: SP_0724
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: SP_0725
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
ykoE
Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
ykoD
Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
ykoC
Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
tenA
Thiaminase II (EC 3.5.99.2)
thiW
Substrate-specific component ThiW of predicted thiazole ECF transporter
thiM
Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)

Position: -302
Score: 68.2
Sequence: AGAGACATTTGGGGT...
Locus tag: SP_0716
Name: tenA
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: SP_0717
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: SP_0718
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
tenA
Thiaminase II (EC 3.5.99.2)
thiM
Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
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