Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulon of TnrA in Bacillus subtilis subsp. subtilis str. 168

Properties
Regulator type: Transcription factor
TF locus tag: BSU13310
Regulator family: MerR
Regulation mode: repressor (activator)
Biological process: Nitrogen assimilation
Effector: NrgB, ammonium uptake protein; NrgA, ammonium uptake protein; Feedback-inhibited GlnA, glutamine synthetase
Regulog: TnrA - Bacillales
Statistics of regulated genes:
- Genes 104
- Operons 44
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 304 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -240
Score: 3.9
Sequence: GGGAAGAAATGATTACA
Position: -61
Score: 5.2
Sequence: TGTTAAAAAATCTAACA
Locus tag: BSU18120
Name: alsT
Funciton: Sodium/alanine symporter family protein
alsT
Sodium/alanine symporter family protein

Position: -40
Score: 4.7
Sequence: TGTTAAATAATTTCACA
Position: 16
Score: 4.2
Sequence: TGTTAGAAGATGGGACA
Locus tag: BSU11190
Name: argC
Funciton: N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)
Locus tag: BSU11200
Name: argJ
Funciton: Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1)
Locus tag: BSU11210
Name: argB
Funciton: Acetylglutamate kinase (EC 2.7.2.8)
Locus tag: BSU11220
Name: argD
Funciton: Acetylornithine aminotransferase (EC 2.6.1.11)
Locus tag: BSU11230
Name: carA
Funciton: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
Locus tag: BSU11240
Name: carB
Funciton: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)
Locus tag: BSU11250
Name: argF
Funciton: Ornithine carbamoyltransferase (EC 2.1.3.3)
argC
N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)
argJ
Glutamate N-acetyltransferase (EC 2.3.1.35) / N-acetylglutamate synthase (EC 2.3.1.1)
argB
Acetylglutamate kinase (EC 2.7.2.8)
argD
Acetylornithine aminotransferase (EC 2.6.1.11)
carA
Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
carB
Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)
argF
Ornithine carbamoyltransferase (EC 2.1.3.3)

Position: -28
Score: 4
Sequence: GGTCAAATTTTCTGATA
Locus tag: BSU27430
Name: glnQ
Funciton: Glutamine transport ATP-binding protein GlnQ (TC 3.A.1.3.2)
Locus tag: BSU27440
Name: glnH
Funciton: Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2)
Locus tag: BSU27450
Name: glnM
Funciton: Glutamine transport system permease protein GlnP (TC 3.A.1.3.2)
Locus tag: BSU27460
Name: glnP
Funciton: Glutamine transport system permease protein GlnP (TC 3.A.1.3.2)
glnQ
Glutamine transport ATP-binding protein GlnQ (TC 3.A.1.3.2)
glnH
Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2)
glnM
Glutamine transport system permease protein GlnP (TC 3.A.1.3.2)
glnP
Glutamine transport system permease protein GlnP (TC 3.A.1.3.2)

Position: -82
Score: 4.3
Sequence: TGTTAAGAATCCTTACA
Position: -59
Score: 5
Sequence: TGACACATAATATAACA
Locus tag: BSU17450
Name: glnR
Funciton: Transcriptional regulator of nitrogen excess response, MerR family
Locus tag: BSU17460
Name: glnA
Funciton: Glutamine synthetase type I (EC 6.3.1.2)
glnR
Transcriptional regulator of nitrogen excess response, MerR family
glnA
Glutamine synthetase type I (EC 6.3.1.2)

Position: -51
Score: 5
Sequence: TGTTAGATTTTATGACC
Locus tag: BSU18450
Name: gltA
Funciton: Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
Locus tag: BSU18440
Name: gltB
Funciton: Glutamate synthase [NADPH] small chain (EC 1.4.1.13)
gltA
Glutamate synthase [NADPH] large chain (EC 1.4.1.13)
gltB
Glutamate synthase [NADPH] small chain (EC 1.4.1.13)

Position: -112
Score: 5
Sequence: GGTCATAAAATCTAACA
Locus tag: BSU18460
Name: gltC
Funciton: Transcriptional regulator of glutamate biosynthesis (LysR family)
gltC
Transcriptional regulator of glutamate biosynthesis (LysR family)

Position: -691
Score: 5.1
Sequence: TGTTATAAAATCTTCCA
Locus tag: BSU28310
Name: ilvB
Funciton: Acetolactate synthase large subunit (EC 2.2.1.6)
Locus tag: BSU28300
Name: ilvH
Funciton: Acetolactate synthase small subunit (EC 2.2.1.6)
Locus tag: BSU28290
Name: ilvC
Funciton: Ketol-acid reductoisomerase (EC 1.1.1.86)
Locus tag: BSU28280
Name: leuA
Funciton: 2-isopropylmalate synthase (EC 2.3.3.13)
Locus tag: BSU28270
Name: leuB
Funciton: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
Locus tag: BSU28260
Name: leuC
Funciton: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Locus tag: BSU28250
Name: leuD
Funciton: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
ilvB
Acetolactate synthase large subunit (EC 2.2.1.6)
ilvH
Acetolactate synthase small subunit (EC 2.2.1.6)
ilvC
Ketol-acid reductoisomerase (EC 1.1.1.86)
leuA
2-isopropylmalate synthase (EC 2.3.3.13)
leuB
3-isopropylmalate dehydrogenase (EC 1.1.1.85)
leuC
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)

Position: -98
Score: 4.9
Sequence: TGTAAGTTTTTGTGACA
Locus tag: BSU03320
Name: nasB
Funciton: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
Locus tag: BSU03310
Name: nasC
Funciton: Assimilatory nitrate reductase large subunit (EC:1.7.99.4)
nasB
Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
nasC
Assimilatory nitrate reductase large subunit (EC:1.7.99.4)

Position: -95
Score: 4.1
Sequence: TCGTATATTTTGTTACA
Position: -85
Score: 5.3
Sequence: TGTTACATTTTATAACA
Locus tag: BSU03300
Name: nasD
Funciton: Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
Locus tag: BSU03290
Name: nasE
Funciton: Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
Locus tag: BSU03280
Name: nasF
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
nasD
Nitrite reductase [NAD(P)H] large subunit (EC 1.7.1.4)
nasE
Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
nasF
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)

Position: -98
Score: 4.9
Sequence: TGTCACAAAAACTTACA
Locus tag: BSU03330
Name: nasA
Funciton: Nitrate/nitrite transporter
nasA
Nitrate/nitrite transporter

Position: -102
Score: 5.2
Sequence: TGTCAGGAAATCTTACA
Locus tag: BSU36510
Name: nrgA
Funciton: Ammonium transporter
Locus tag: BSU36520
Name: nrgB
Funciton: Nitrogen regulatory protein P-II
nrgA
Ammonium transporter
nrgB
Nitrogen regulatory protein P-II

Position: -119
Score: 4.1
Sequence: TGTAATAATATACAACT
Locus tag: BSU11360
Name: appD
Funciton: Oligopeptide ABC transporter (ATP-binding protein)
Locus tag: BSU11370
Name: appF
Funciton: oligopeptide ABC transporter (ATP-binding protein)
Locus tag: BSU11381
Name: appA
Funciton: Oligopeptide ABC transporter (substrate-binding)
Locus tag: BSU11382
Name: appA
Funciton: Oligopeptide ABC transporter (substrate-binding)
Locus tag: BSU11390
Name: appB
Funciton: Oligopeptide ABC transporter (permease)
Locus tag: BSU11400
Name: appC
Funciton: Oligopeptide ABC transporter (permease)
appD
Oligopeptide ABC transporter (ATP-binding protein)
appF
oligopeptide ABC transporter (ATP-binding protein)
appA
Oligopeptide ABC transporter (substrate-binding)
appA
Oligopeptide ABC transporter (substrate-binding)
appB
Oligopeptide ABC transporter (permease)
appC
Oligopeptide ABC transporter (permease)

Position: -231
Score: 4.3
Sequence: TGGAAGAAAAACTAACG
Locus tag: BSU11430
Name: oppA
Funciton: Oligopeptide ABC transporter (binding lipoprotein)
Locus tag: BSU11440
Name: oppB
Funciton: Oligopeptide ABC transporter (permease)
Locus tag: BSU11450
Name: oppC
Funciton: Oligopeptide ABC transporter (permease)
Locus tag: BSU11460
Name: oppD
Funciton: Oligopeptide ABC transporter (ATP-binding protein)
Locus tag: BSU11470
Name: oppF
Funciton: Oligopeptide ABC transporter (ATP-binding protein)
oppA
Oligopeptide ABC transporter (binding lipoprotein)
oppB
Oligopeptide ABC transporter (permease)
oppC
Oligopeptide ABC transporter (permease)
oppD
Oligopeptide ABC transporter (ATP-binding protein)
oppF
Oligopeptide ABC transporter (ATP-binding protein)

Position: -43
Score: 4.9
Sequence: TGGAATAAAATCTCACA
Locus tag: BSU07560
Name: pel
Funciton: Pectate lyase precursor (EC 4.2.2.2)
pel
Pectate lyase precursor (EC 4.2.2.2)

Position: -98
Score: 4.4
Sequence: GGGAAGATTATGTTACA
Locus tag: BSU35900
Name: capB
Funciton: Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
Locus tag: BSU35890
Name: capC
Funciton: Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
Locus tag: BSU35880
Name: capA
Funciton: Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
Locus tag: BSU35870
Name: capE
Funciton: Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
Locus tag: BSU35860
Name: pgdS
Funciton: Gamma-DL-glutamyl hydrolase PgsS (EC 3.4.19.-)
capB
Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
capC
Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
capA
Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
capE
Poly-gamma-glutamate synthase subunit (EC 6.3.2.-)
pgdS
Gamma-DL-glutamyl hydrolase PgsS (EC 3.4.19.-)

Position: -125
Score: 4.7
Sequence: TGTTTCATTTTCTGACA
Position: -101
Score: 4
Sequence: AGTCATTTTTTCTTCCA
Locus tag: BSU32510
Name: pucA
Funciton: Xanthine dehydrogenase subunit A
Locus tag: BSU32500
Name: pucB
Funciton: Xanthine dehydrogenase
Locus tag: BSU32490
Name: pucC
Funciton: Xanthine dehydrogenase, FAD binding subunit (EC 1.17.1.4)
Locus tag: BSU32480
Name: pucD
Funciton: Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4)
Locus tag: BSU32470
Name: pucE
Funciton: xanthine dehydrogenase, iron-sulfur subunit
pucA
Xanthine dehydrogenase subunit A
pucB
Xanthine dehydrogenase
pucC
Xanthine dehydrogenase, FAD binding subunit (EC 1.17.1.4)
pucD
Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4)
pucE
xanthine dehydrogenase, iron-sulfur subunit

Position: -140
Score: 5.3
Sequence: TGTTACATTTTCTTACA
Position: -34
Score: 3.9
Sequence: TGTTACTAAAGTTCACA
Locus tag: BSU32430
Name: pucJ
Funciton: Xanthine permease
Locus tag: BSU32440
Name: pucK
Funciton: Xanthine permease
Locus tag: BSU32450
Name: pucL
Funciton: 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (EC 4.1.1.n1) / Uricase (EC 1.7.3.3)
Locus tag: BSU32460
Name: pucM
Funciton: 5-hydroxyisourate hydrolase
pucJ
Xanthine permease
pucK
Xanthine permease
pucL
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (EC 4.1.1.n1) / Uricase (EC 1.7.3.3)
pucM
5-hydroxyisourate hydrolase

Position: -51
Score: 5.1
Sequence: TGTTACATAAACTGACA
Locus tag: BSU32410
Name: pucH
Funciton: Allantoinase (EC 3.5.2.5)
pucH
Allantoinase (EC 3.5.2.5)

Position: -140
Score: 5.1
Sequence: TGTCAGTTTATGTAACA
Locus tag: BSU32420
Name: pucR
Funciton: Transcriptional regulator of the purine degradation operon, PucR family
pucR
Transcriptional regulator of the purine degradation operon, PucR family

Position: -135
Score: 4.3
Sequence: TGTGTCATTATCTCACA
Locus tag: BSU25289
Name: yqzL
Funciton: Hypothetical protein
Locus tag: BSU25280
Name: recO
Funciton: DNA recombination and repair protein RecO
yqzL
Hypothetical protein
recO
DNA recombination and repair protein RecO

Position: -124
Score: 3.9
Sequence: TGTTAATTTTTCTTCCG
Position: -81
Score: 5.5
Sequence: TGTTAGAAAATATGACA
Locus tag: BSU13310
Name: tnrA
Funciton: Transcriptional regulator of nitrogen assimilation, MerR family
tnrA
Transcriptional regulator of nitrogen assimilation, MerR family

Position: -84
Score: 3.9
Sequence: TGAGAGAAAAGCTGACT
Locus tag: BSU02690
Name: ansZ
Funciton: L-asparaginase (EC 3.5.1.1)
ansZ
L-asparaginase (EC 3.5.1.1)

Position: -121
Score: 4.9
Sequence: CGTGAGATTTTCTTACA
Locus tag: BSU03680
Name: yclG
Funciton: Pectate lyase family protein
yclG
Pectate lyase family protein

Position: -145
Score: 4.9
Sequence: TGGTAGGTTTTCTGACA
Position: -52
Score: 3.9
Sequence: CGGGACAATAAATGACA
Locus tag: BSU04050
Name: lamB
Funciton: Lactam utilization protein LamB
Locus tag: BSU04060
Name: ycsG
Funciton: Permease (transport protein)
Locus tag: BSU04070
Name: ycsI
Funciton: Hypothetical protein
Locus tag: BSU04080
Name: kipI
Funciton: Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54)
Locus tag: BSU04090
Name: kipA
Funciton: Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54)
Locus tag: BSU04100
Name: kipR
Funciton: Transcriptional regulator of initiation of developmental transcription at the onset of sporulation, IclR family
lamB
Lactam utilization protein LamB
ycsG
Permease (transport protein)
ycsI
Hypothetical protein
kipI
Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54)
kipA
Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54)
kipR
Transcriptional regulator of initiation of developmental transcription at the onset of sporulation, IclR family

Position: -55
Score: 4.5
Sequence: AGGAAGAAAATCTAACA
Locus tag: BSU04170
Name: ydaB
Funciton: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
ydaB
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Position: -130
Score: 5.5
Sequence: TGTCATATTTTCTAACA
Position: -87
Score: 3.9
Sequence: CGGAAGAAAAATTAACA
Locus tag: BSU13320
Name: ykzB
Funciton: Hypothetical protein
Locus tag: BSU13330
Name: ykoL
Funciton: Hypothetical protein
ykzB
Hypothetical protein
ykoL
Hypothetical protein

Position: -61
Score: 4.8
Sequence: TGTGATCTTTTCTTACA
Locus tag: BSU19579
Name: yhjC
Funciton: Hypothetical protein
Locus tag: BSU19580
Name: yodF
Funciton: Na+/solute symporter
yhjC
Hypothetical protein
yodF
Na+/solute symporter

Position: -96
Score: 4.9
Sequence: GGTCATATAATGTGACA
Locus tag: BSU27810
Name: yrbD
Funciton: Sodium/proton-dependent alanine transporter
yrbD
Sodium/proton-dependent alanine transporter

Position: -141
Score: 5.1
Sequence: TGGAAGATTTTATAACA
Position: -97
Score: 4
Sequence: TGACAGATCATCTTGCA
Locus tag: BSU28320
Name: ysnD
Funciton: Hypothetical protein
Locus tag: BSU28330
Name: ysnE
Funciton: GNAT family acetyltransferase
ysnD
Hypothetical protein
ysnE
GNAT family acetyltransferase

Position: -63
Score: 4.6
Sequence: CGTGAAAAAATCTAACA
Position: 19
Score: 3.7
Sequence: TCTTAGGTTTTCTGGCA
Locus tag: BSU30360
Name: yttA
Funciton: Hypothetical protein
yttA
Hypothetical protein

Position: -78
Score: 4.4
Sequence: TGTCACATGATCTGACT
Locus tag: BSU32090
Name: yuiA
Funciton: Uncharacterized conserved protein contain two CXXC motifs
Locus tag: BSU32080
Name: yuiB
Funciton: Hypothetical protein
Locus tag: BSU32070
Name: yuiC
Funciton: Hypothetical protein
yuiA
Uncharacterized conserved protein contain two CXXC motifs
yuiB
Hypothetical protein
yuiC
Hypothetical protein

Position: -43
Score: 4.6
Sequence: TGGTATAATTAATAACA
Locus tag: BSU32110
Name: yumC
Funciton: Thioredoxin reductase (EC 1.8.1.9)
yumC
Thioredoxin reductase (EC 1.8.1.9)

Position: -39
Score: 4.8
Sequence: CGTCAGAAAATTTAACA
Locus tag: BSU33460
Name: yvgT
Funciton: Hypothetical membrane protein
yvgT
Hypothetical membrane protein

Position: -53
Score: 5.1
Sequence: TGTCAGAAAAAATAACA
Locus tag: BSU37950
Name: ywdI
Funciton: Hypothetical protein
Locus tag: BSU37940
Name: ywdJ
Funciton: Xanthine permease
Locus tag: BSU37930
Name: ywdK
Funciton: Uncharacterized small membrane protein
ywdI
Hypothetical protein
ywdJ
Xanthine permease
ywdK
Uncharacterized small membrane protein

Position: -154
Score: 4.7
Sequence: TGTCAGAAAATCTGCAA
Locus tag: BSU36920
Name: rpiB
Funciton: Ribose 5-phosphate isomerase B (EC 5.3.1.6)
Locus tag: BSU36910
Name: ywlG
Funciton: Hypothetical protein ywlG
rpiB
Ribose 5-phosphate isomerase B (EC 5.3.1.6)
ywlG
Hypothetical protein ywlG

Position: -83
Score: 4
Sequence: CGTCAGTTTTTCTGCCG
Locus tag: BSU36100
Name: ywrD
Funciton: Gamma-glutamyltranspeptidase (EC 2.3.2.2)
ywrD
Gamma-glutamyltranspeptidase (EC 2.3.2.2)

Position: -66
Score: 4.6
Sequence: TGTGACATCTTCTTACA
Locus tag: BSU40470
Name: yycC
Funciton: Hypothetical protein
Locus tag: BSU40480
Name: yycB
Funciton: Cyanate MFS transporter
Locus tag: BSU40490
Name: yycA
Funciton: Putative glycosyl transferase
yycC
Hypothetical protein
yycB
Cyanate MFS transporter
yycA
Putative glycosyl transferase

Position: -212
Score: 3.6
Sequence: TCTAAAATTTTATTAAA
Position: -175
Score: 4.9
Sequence: TGTAAGAAAATCTCACG
Locus tag: BSU03670
Name: yclF
Funciton: Di-tripeptide-proton ABC symporter
yclF
Di-tripeptide-proton ABC symporter

Position: -159
Score: 3.7
Sequence: TGGAAGGAACGATGACA
Locus tag: BSU35490
Name: degU
Funciton: Transcriptional regulator essential for degradative enzyme expression and competence regulation, OmpR family
degU
Transcriptional regulator essential for degradative enzyme expression and competence regulation, OmpR family

Position: -117
Score: 3.6
Sequence: TGTAACTATAAATGATA
Position: -31
Score: 4.1
Sequence: TCGTACATTTTATTACA
Locus tag: BSU38850
Name: yxkC
Funciton: Hypothetical protein
yxkC
Hypothetical protein

Position: -48
Score: 4.4
Sequence: TATGATAAAATATAACA
Locus tag: BSU02820
Name: rapJ
Funciton: Response regulator aspartate phosphatase I (EC 3.1.-.-)
rapJ
Response regulator aspartate phosphatase I (EC 3.1.-.-)

Position: -78
Score: 4.3
Sequence: AGTTATATTAAGTGACA
Position: -66
Score: 3.7
Sequence: TGACATCTAATGTCAAA
Position: -56
Score: 4.3
Sequence: TGTCAAAAAACATAACG
Locus tag: BSU36470
Name: pucI
Funciton: Allantoin permease
Locus tag: BSU36460
Name: ywoF
Funciton: Pectin lyase like protein
pucI
Allantoin permease
ywoF
Pectin lyase like protein

Position: -103
Score: 5.1
Sequence: TGGTATATTTTCTTACA
Locus tag: BSU06310
Name: gabP
Funciton: Gamma-aminobutyrate (GABA) permease
gabP
Gamma-aminobutyrate (GABA) permease

Position: -938
Score: 4.5
Sequence: TGTGAATAAATATAACA
Position: -833
Score: 4.6
Sequence: TGTAAACTTTTATAACA
Locus tag: BSU36660
Name: ureA
Funciton: Urease gamma subunit (EC 3.5.1.5)
Locus tag: BSU36650
Name: ureB
Funciton: Urease beta subunit (EC 3.5.1.5)
Locus tag: BSU36640
Name: ureC
Funciton: Urease alpha subunit (EC 3.5.1.5)
ureA
Urease gamma subunit (EC 3.5.1.5)
ureB
Urease beta subunit (EC 3.5.1.5)
ureC
Urease alpha subunit (EC 3.5.1.5)
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