Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog NrdR - Clostridia-3

Properties
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Deoxyribonucleotide biosynthesis
Effector: Deoxyribonucleotides
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 49 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Bacteroides pectinophilus ATCC 43243 3 2
Blautia hansenii DSM 20583 3 2
Bryantella formatexigens DSM 14469 1 1
Clostridiales bacterium 1_7_47_FAA 4 2
Clostridium bolteae ATCC BAA-613 2 1
Clostridium nexile DSM 1787 4 2
Clostridium scindens ATCC 35704 6 3
Dorea formicigenerans ATCC 27755 1 1
Dorea longicatena DSM 13814 2 2
Eubacterium eligens ATCC 27750 1 1
Eubacterium rectale ATCC 33656 1 1
Roseburia intestinalis L1-82 2 1
Ruminococcus gnavus ATCC 29149 5 3
Ruminococcus lactaris ATCC 29176 2 1
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
nrdD
*2
Bacteroides pectinophilus ATCC 43243

Site:
position = -147
score = 5.11295
sequence = GCACAATATATTGTTT

Site:
position = -116
score = 3.88826
sequence = TTTCTATATTTGGTAG

Gene: BACPEC_00926: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)

Site:
position = -159
score = 4.12183
sequence = ACGCAATATTTGGTAA

Site:
position = -128
score = 4.47345
sequence = TATCTATATATTGTGG

Gene: BACPEC_00140: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
*
Clostridiales bacterium 1_7_47_FAA

Site:
position = -141
score = 4.80858
sequence = ACACAACATTTAGTGC

Site:
position = -173
score = 3.83212
sequence = ATACATCCTATCGTAT

Gene: Cbac1_010100006828: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
*
Clostridium bolteae ATCC BAA-613

Site:
position = -171
score = 3.96011
sequence = ATACATCTTATCGTAT

Site:
position = -140
score = 4.98145
sequence = ACACAACATTTAGTGG

Gene: CLOBOL_02823: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
 
Clostridium nexile DSM 1787
*
Clostridium scindens ATCC 35704

Site:
position = -67
score = 4.58667
sequence = GTGCTAGATATTGTAT

Site:
position = -35
score = 4.08906
sequence = AACCAACATTTAGTGG

Site:
position = -135
score = 4.44694
sequence = AAAGTAAATATTGTAT

Gene: CLOSCI_01031: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
*
Dorea formicigenerans ATCC 27755

Site:
position = -162
score = 4.21833
sequence = ACGCCATATTTTGTAG

Site:
position = -129
score = 5.03846
sequence = ACACAATATCTTGTGA

Site:
position = -64
score = 4.8777
sequence = ACACAAGATGTTGTGG

Gene: DORFOR_02443: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
*
Dorea longicatena DSM 13814

Site:
position = -102
score = 4.56888
sequence = GCACAATATCTTGTGC

Site:
position = -70
score = 4.9584
sequence = AAACAATATTTAGTAG

Gene: DORLON_00953: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
*
Eubacterium eligens ATCC 27750

Site:
position = -178
score = 5.07151
sequence = TTACAAGATATTGTGT

Site:
position = -146
score = 4.58088
sequence = AGCCTATATGTTGTAT

Gene: EUBELI_01571: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
*
Eubacterium rectale ATCC 33656

Site:
position = -284
score = 4.73032
sequence = CTACAAAATATTGTTG

Site:
position = -253
score = 4.85465
sequence = CAACAATATCTTGTAT

Site:
position = -26
score = 5.50789
sequence = ATACTATATATAGTAC

Gene: EUBREC_2400: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
*2
Roseburia intestinalis L1-82

Gene: ROSINTL182_03098: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)

Site:
position = -95
score = 5.85257
sequence = ACACAATATATTGTAT

Gene: ROSINTL182_03097: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
 
Ruminococcus gnavus ATCC 29149

Gene: RUMGNA_00011: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
*
Ruminococcus lactaris ATCC 29176

Site:
position = 19
score = 5.52515
sequence = ATACTATATTTTGTAT

Site:
position = 48
score = 4.12511
sequence = AGACAATATCTTGAAA

Gene: RUMLAC_00868: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
nrdG
 
Bacteroides pectinophilus ATCC 43243

Gene: BACPEC_00927: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100006823: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02822: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_01030: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Dorea formicigenerans ATCC 27755

Gene: DORFOR_02441: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Dorea longicatena DSM 13814

Gene: DORLON_00951: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Eubacterium eligens ATCC 27750

Gene: EUBELI_20493: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149

Gene: RUMGNA_00010: anaerobic ribonucleoside-triphosphate reductase activating protein
 
Ruminococcus lactaris ATCC 29176

Gene: RUMLAC_00869: anaerobic ribonucleoside-triphosphate reductase activating protein
anaerobic ribonucleoside-triphosphate reductase activating protein
 
CRON 2.
ligA
 
Bacteroides pectinophilus ATCC 43243
*
Blautia hansenii DSM 20583

Site:
position = -123
score = 5.04546
sequence = ACACTATATATCGTTT

Site:
position = -153
score = 5.61079
sequence = ACACTATATGTAGTAT

Site:
position = -92
score = 4.8276
sequence = TTACTATATATAGAGG

Gene: BLAHAN_00802: NAD-dependent DNA ligase
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA
 
Clostridium bolteae ATCC BAA-613
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_03783: NAD-dependent DNA ligase
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
*
Ruminococcus gnavus ATCC 29149

Site:
position = -153
score = 5.61079
sequence = ACACTATATGTAGTAT

Site:
position = -123
score = 5.04546
sequence = ACACTATATATCGTTT

Site:
position = -92
score = 4.8276
sequence = TTACTATATATAGAGG

Gene: RUMGNA_01429: NAD-dependent DNA ligase
 
Ruminococcus lactaris ATCC 29176
NAD-dependent DNA ligase
 
CRON 3.
nrdE
 
Bacteroides pectinophilus ATCC 43243
*
Blautia hansenii DSM 20583

Site:
position = -41
score = 5.42914
sequence = ATACAAGATATAGTAT

Gene: BLAHAN_01704: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100012710: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02577: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
*
Clostridium nexile DSM 1787

Site:
position = -60
score = 5.07322
sequence = CAACTATATATTGTGG

Site:
position = -28
score = 4.98436
sequence = ATACTATAAATAGTAA

Gene: CLONEX_03145: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
*
Clostridium scindens ATCC 35704

Site:
position = -64
score = 5.06548
sequence = CAACAATATATTGTGG

Site:
position = -33
score = 4.43605
sequence = AATCAATAAATTGTAT

Gene: CLOSCI_02889: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
*
Ruminococcus gnavus ATCC 29149

Site:
position = -78
score = 4.80932
sequence = ATCCAATATCTTGTGT

Site:
position = -48
score = 5.27176
sequence = CCACTATATTTTGTAT

Gene: RUMGNA_02624: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Ruminococcus lactaris ATCC 29176
Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
nrdF
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583

Gene: BLAHAN_01705: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100012705: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02576: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
Clostridium nexile DSM 1787

Gene: CLONEX_03144: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_02888: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149

Gene: RUMGNA_02625: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
Ruminococcus lactaris ATCC 29176
Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
CRON 4.
nrdD2
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583
*
Bryantella formatexigens DSM 14469

Site:
position = -110
score = 4.7903
sequence = ACACTATATATTGATG

Site:
position = -142
score = 4.41178
sequence = ATACTCTATTTAGTAC

Gene: BRYFOR_03555: Oxygen-sensitive ribonucleoside-triphosphate reductase (EC 1.17.4.2)
*
Clostridiales bacterium 1_7_47_FAA

Site:
position = -144
score = 5.04969
sequence = ACACAATATCTAGTTT

Site:
position = -127
score = 4.10208
sequence = ACACAAAATGTTATAC

Gene: Cbac1_010100017114: Oxygen-sensitive ribonucleoside-triphosphate reductase (EC 1.17.4.2)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_06849: Oxygen-sensitive ribonucleoside-triphosphate reductase (EC 1.17.4.2)
*
Clostridium nexile DSM 1787

Site:
position = -122
score = 4.33424
sequence = TAACAATATATAGGAA

Site:
position = -91
score = 4.90973
sequence = ACACAATATATGGTTT

Gene: CLONEX_02838: Oxygen-sensitive ribonucleoside-triphosphate reductase (EC 1.17.4.2)
*
Clostridium scindens ATCC 35704

Site:
position = -96
score = 4.39897
sequence = ACACAATAAGTGGTAT

Site:
position = -129
score = 4.79611
sequence = GCACAATATATTGTTA

Site:
position = -160
score = 4.79611
sequence = TAACAATATATTGTGC

Gene: CLOSCI_01639: Oxygen-sensitive ribonucleoside-triphosphate reductase (EC 1.17.4.2)
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
*
Ruminococcus gnavus ATCC 29149

Site:
position = -91
score = 4.0261
sequence = ATACTAGATGTTGGTG

Site:
position = -44
score = 4.28964
sequence = ACACTAAATACAGCGT

Gene: RUMGNA_02734: Oxygen-sensitive ribonucleoside-triphosphate reductase (EC 1.17.4.2)
 
Ruminococcus lactaris ATCC 29176
Oxygen-sensitive ribonucleoside-triphosphate reductase (EC 1.17.4.2)
COG0345
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583

Gene: BLAHAN_00380: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
 
Bryantella formatexigens DSM 14469

Gene: BRYFOR_04808: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
 
Clostridiales bacterium 1_7_47_FAA
 
Clostridium bolteae ATCC BAA-613
 
Clostridium nexile DSM 1787

Gene: CLONEX_02839: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_01601: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
 
Dorea formicigenerans ATCC 27755

Gene: DORFOR_03282: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
*
Dorea longicatena DSM 13814

Site:
position = -74
score = 3.7892
sequence = ACATAACAGATTGTTT

Gene: DORLON_01167: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656

Gene: EUBREC_1178: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149

Gene: RUMGNA_02726: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
 
Ruminococcus lactaris ATCC 29176

Gene: RUMLAC_01681: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
Pyrroline-5-carboxylate reductase (EC 1.5.1.2)
Cbac1_010100017119
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100017119: hypothetical protein
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_06848: hypothetical protein
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149
 
Ruminococcus lactaris ATCC 29176
hypothetical protein
COG0492
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469

Gene: BRYFOR_01585: thioredoxin reductase
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100029421: thioredoxin reductase
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_05920: thioredoxin reductase
 
Clostridium nexile DSM 1787

Gene: CLONEX_03825: thioredoxin reductase
 
Clostridium scindens ATCC 35704

Gene: CLOSCI_01638: thioredoxin reductase
 
Dorea formicigenerans ATCC 27755

Gene: DORFOR_00179: thioredoxin reductase
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149

Gene: RUMGNA_02735: thioredoxin reductase
 
Ruminococcus lactaris ATCC 29176

Gene: RUMLAC_01680: thioredoxin reductase
thioredoxin reductase
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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