Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog BioQ - Frankineae/Propionibacterineae/Pseudonocardiaceae

Properties
Regulator type: Transcription factor
Regulator family: TetR
Regulation mode: repressor
Biological process: Biotin biosynthesis
Effector: Biotin
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 11 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Actinosynnema mirum DSM 43827
Saccharopolyspora erythraea NRRL 2338 4 2
Saccharomonospora viridis DSM 43017
Nakamurella multipartita DSM 44233
Frankia sp. EAN1pec
Frankia sp. CcI3
Acidothermus cellulolyticus 11B
Propionibacterium acnes KPA171202 8 5
Nocardioides sp. JS614 8 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
bioB
 
Actinosynnema mirum DSM 43827
*
Saccharopolyspora erythraea NRRL 2338

Site:
position = -63
score = 6.25966
sequence = CCTGAACGGCGTTCAGG

Gene: SACE_4683: Biotin synthase (EC 2.8.1.6)
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
*
Propionibacterium acnes KPA171202

Site:
position = 9
score = 4.63055
sequence = ATTGAATCCCGTTCAAT

Site:
position = 26
score = 6.25966
sequence = CCTGAACGGCGTTCAGG

Gene: PPA1407: Biotin synthase (EC 2.8.1.6)
*
Nocardioides sp. JS614

Site:
position = -36
score = 6.17558
sequence = CCTGAACGCTGTTCAGG

Gene: Noca_3415: Biotin synthase (EC 2.8.1.6)
Biotin synthase (EC 2.8.1.6)
bioA
 
Actinosynnema mirum DSM 43827
 
Saccharopolyspora erythraea NRRL 2338

Gene: SACE_4684: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
*
Propionibacterium acnes KPA171202

Site:
position = -121
score = 5.91266
sequence = CCTGAACACTGTTCAAG

Gene: PPA0967: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
 
Nocardioides sp. JS614

Gene: Noca_3414: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
bioF
 
Actinosynnema mirum DSM 43827
 
Saccharopolyspora erythraea NRRL 2338

Gene: SACE_4685: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
 
Propionibacterium acnes KPA171202
 
Nocardioides sp. JS614

Gene: Noca_3413: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
8-amino-7-oxononanoate synthase (EC 2.3.1.47)
bioD
 
Actinosynnema mirum DSM 43827
 
Saccharopolyspora erythraea NRRL 2338
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
 
Propionibacterium acnes KPA171202

Gene: PPA0968: Dethiobiotin synthetase (EC 6.3.3.3)
 
Nocardioides sp. JS614

Gene: Noca_3412: Dethiobiotin synthetase (EC 6.3.3.3)
Dethiobiotin synthetase (EC 6.3.3.3)
bioY
 
Actinosynnema mirum DSM 43827
 
Saccharopolyspora erythraea NRRL 2338
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
*
Propionibacterium acnes KPA171202

Site:
position = -75
score = 5.63909
sequence = ACTGAACGGTGTTCAAT

Gene: PPA1400: Substrate-specific component BioY of biotin ECF transporter
*
Nocardioides sp. JS614

Site:
position = -39
score = 5.77142
sequence = CCTGACCACCGTTCAGG

Gene: Noca_3349: Substrate-specific component BioY of biotin ECF transporter
Substrate-specific component BioY of biotin ECF transporter
bioM
 
Actinosynnema mirum DSM 43827
 
Saccharopolyspora erythraea NRRL 2338
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
 
Propionibacterium acnes KPA171202

Gene: PPA1399: ATPase component BioM of energizing module of biotin ECF transporter
 
Nocardioides sp. JS614

Gene: Noca_3350: ATPase component BioM of energizing module of biotin ECF transporter
ATPase component BioM of energizing module of biotin ECF transporter
bioN
 
Actinosynnema mirum DSM 43827
 
Saccharopolyspora erythraea NRRL 2338
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
 
Propionibacterium acnes KPA171202

Gene: PPA1398: Transmembrane component BioN of energizing module of biotin ECF transporter
 
Nocardioides sp. JS614

Gene: Noca_3351: Transmembrane component BioN of energizing module of biotin ECF transporter
Transmembrane component BioN of energizing module of biotin ECF transporter
 
CRON 2.
bioWF
 
Actinosynnema mirum DSM 43827
 
Saccharopolyspora erythraea NRRL 2338
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
*
Propionibacterium acnes KPA171202

Site:
position = -50
score = 5.05611
sequence = ATTGAATGGTGTTCAAT

Gene: PPA1866: Pimeloyl-CoA synthase (EC 6.2.1.14) / 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
 
Nocardioides sp. JS614
Pimeloyl-CoA synthase (EC 6.2.1.14) / 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
 
CRON 3.
bioQ
 
Actinosynnema mirum DSM 43827
*
Saccharopolyspora erythraea NRRL 2338

Site:
position = -58
score = 6.25966
sequence = CCTGAACGCCGTTCAGG

Gene: SACE_4682: Biotin repressor, TetR family
 
Saccharomonospora viridis DSM 43017
 
Nakamurella multipartita DSM 44233
 
Frankia sp. EAN1pec
 
Frankia sp. CcI3
 
Acidothermus cellulolyticus 11B
*
Propionibacterium acnes KPA171202

Site:
position = -55
score = 6.25966
sequence = CCTGAACGCCGTTCAGG

Gene: PPA1406: Biotin repressor, TetR family
*
Nocardioides sp. JS614

Site:
position = -95
score = 5.77142
sequence = CCTGAACGGTGGTCAGG

Gene: Noca_3348: Biotin repressor, TetR family
Biotin repressor, TetR family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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