Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog Rex - Nocardiaceae

Properties
Regulator type: Transcription factor
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 22 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Nocardia farcinica IFM 10152 5 2
Rhodococcus erythropolis PR4 9 4
Rhodococcus opacus B4 35 8
Rhodococcus sp. RHA1 35 8
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
pntAa
 
Nocardia farcinica IFM 10152

Gene: nfa10130: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
 
Rhodococcus erythropolis PR4

Gene: RER_39990: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
*
Rhodococcus opacus B4

Site:
position = -215
score = 4.66888
sequence = CTGTGATCGGGTTCACAA

Gene: ROP_12860: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
*
Rhodococcus sp. RHA1

Site:
position = -215
score = 4.9109
sequence = CTGTGACCGGGTTCACAA

Gene: RHA1_ro01583: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
pntAb
 
Nocardia farcinica IFM 10152

Gene: nfa10140: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
 
Rhodococcus erythropolis PR4

Gene: RER_39980: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
 
Rhodococcus opacus B4

Gene: ROP_12850: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro01582: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
pntB
 
Nocardia farcinica IFM 10152

Gene: nfa10150: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)
 
Rhodococcus erythropolis PR4

Gene: RER_39970: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)
 
Rhodococcus opacus B4

Gene: ROP_12840: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro01581: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)
NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)
 
CRON 2.
coxM
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
*
Rhodococcus opacus B4

Site:
position = -17
score = 4.42949
sequence = TTGTGAGGTAGGTCACAA

Gene: ROP_52770: Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)
*
Rhodococcus sp. RHA1

Site:
position = -17
score = 4.42949
sequence = TTGTGAGGTAGGTCACAA

Gene: RHA1_ro05230: Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)
Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)
coxS
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
 
Rhodococcus opacus B4

Gene: ROP_52780: Carbon monoxide dehydrogenase small chain (EC 1.2.99.2)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05231: Carbon monoxide dehydrogenase small chain (EC 1.2.99.2)
Carbon monoxide dehydrogenase small chain (EC 1.2.99.2)
coxL
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
 
Rhodococcus opacus B4

Gene: ROP_52790: Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 )
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05232: Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 )
Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 )
coxF
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
 
Rhodococcus opacus B4

Gene: ROP_52800: Carbon monoxide dehydrogenase F protein
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05233: Carbon monoxide dehydrogenase F protein
Carbon monoxide dehydrogenase F protein
coxD
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
 
Rhodococcus opacus B4

Gene: ROP_52810: Carbon monoxide dehydrogenase D protein
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05234: Carbon monoxide dehydrogenase D protein
Carbon monoxide dehydrogenase D protein
coxG
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
 
Rhodococcus opacus B4

Gene: ROP_52820: Carbon monoxide dehydrogenase G protein
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05235: Carbon monoxide dehydrogenase G protein
Carbon monoxide dehydrogenase G protein
coxE
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
 
Rhodococcus opacus B4

Gene: ROP_52830: Carbon monoxide dehydrogenase E protein
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05236: Carbon monoxide dehydrogenase E protein
Carbon monoxide dehydrogenase E protein
 
CRON 3.
rex
*
Nocardia farcinica IFM 10152

Site:
position = -179
score = 5.61866
sequence = TTGTGCATGGCTTCACAA

Gene: nfa51710: Redox-sensitive transcriptional regulator Rex
*
Rhodococcus erythropolis PR4

Site:
position = -127
score = 5.77599
sequence = TTGTGCATGGGTTCACAA

Gene: RER_16400: Redox-sensitive transcriptional regulator Rex
*
Rhodococcus opacus B4

Site:
position = -164
score = 5.77599
sequence = TTGTGCATGGGTTCACAA

Gene: ROP_17260: Redox-sensitive transcriptional regulator Rex
*
Rhodococcus sp. RHA1

Site:
position = 22
score = 5.77599
sequence = TTGTGCATGGGTTCACAA

Gene: RHA1_ro02054: Redox-sensitive transcriptional regulator Rex
Redox-sensitive transcriptional regulator Rex
hemA
 
Nocardia farcinica IFM 10152

Gene: nfa51700: Glutamyl-tRNA reductase (EC 1.2.1.70)
 
Rhodococcus erythropolis PR4

Gene: RER_16410: Glutamyl-tRNA reductase (EC 1.2.1.70)
 
Rhodococcus opacus B4

Gene: ROP_17250: Glutamyl-tRNA reductase (EC 1.2.1.70)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro02053: Glutamyl-tRNA reductase (EC 1.2.1.70)
Glutamyl-tRNA reductase (EC 1.2.1.70)
hemC
 
Nocardia farcinica IFM 10152

Gene: nfa51690: Porphobilinogen deaminase (EC 2.5.1.61)
 
Rhodococcus erythropolis PR4

Gene: RER_16420: Porphobilinogen deaminase (EC 2.5.1.61)
 
Rhodococcus opacus B4

Gene: ROP_17240: Porphobilinogen deaminase (EC 2.5.1.61)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro02052: Porphobilinogen deaminase (EC 2.5.1.61)
Porphobilinogen deaminase (EC 2.5.1.61)
hemD
 
Nocardia farcinica IFM 10152

Gene: nfa51680: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
 
Rhodococcus erythropolis PR4

Gene: RER_16430: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
 
Rhodococcus opacus B4

Gene: ROP_17230: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro02051: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
hemB
 
Nocardia farcinica IFM 10152

Gene: nfa51660: Porphobilinogen synthase (EC 4.2.1.24)
 
Rhodococcus erythropolis PR4

Gene: RER_16440: Porphobilinogen synthase (EC 4.2.1.24)
 
Rhodococcus opacus B4

Gene: ROP_17220: Porphobilinogen synthase (EC 4.2.1.24)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro02050: Porphobilinogen synthase (EC 4.2.1.24)
Porphobilinogen synthase (EC 4.2.1.24)
 
CRON 4.
choD
 
Nocardia farcinica IFM 10152

Gene: nfa26130: Cholesterol oxidase (EC 1.1.3.6)
*
Rhodococcus erythropolis PR4

Site:
position = -69
score = 5.67643
sequence = TTGTGGTGGTAGTCACAA

Gene: RER_19350: Cholesterol oxidase (EC 1.1.3.6)
*
Rhodococcus opacus B4

Site:
position = -71
score = 5.85569
sequence = TTGTGGCAGTTGTCACAA

Gene: ROP_62610: Cholesterol oxidase (EC 1.1.3.6)
*
Rhodococcus sp. RHA1

Site:
position = -71
score = 5.85569
sequence = TTGTGGCAGCTGTCACAA

Gene: RHA1_ro06201: Cholesterol oxidase (EC 1.1.3.6)
Cholesterol oxidase (EC 1.1.3.6)
 
CRON 5.
fadD
 
Nocardia farcinica IFM 10152
*
Rhodococcus erythropolis PR4

Site:
position = -89
score = 4.54318
sequence = TTGTGACTGTCGTCACGG

Gene: RER_16190: Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )
*
Rhodococcus opacus B4

Site:
position = -9
score = 5.17655
sequence = CTGTGACTGGTGTCACAA

Gene: ROP_17430: Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )
*
Rhodococcus sp. RHA1

Site:
position = -95
score = 5.24672
sequence = TTGTGACTGTTGTCACAG

Gene: RHA1_ro02071: Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )
Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )
gpm
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4

Gene: RER_16200: Phosphoglycerate mutase (EC 5.4.2.1)
 
Rhodococcus opacus B4

Gene: ROP_17420: Phosphoglycerate mutase (EC 5.4.2.1)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro02070: Phosphoglycerate mutase (EC 5.4.2.1)
Phosphoglycerate mutase (EC 5.4.2.1)
 
CRON 6.
dhaS
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4
*
Rhodococcus opacus B4

Site:
position = -40
score = 5.43269
sequence = TTGTGACAGCCATCACAA

Gene: ROP_25550: Acetaldehyde dehydrogenase (EC 1.2.1.10)
*
Rhodococcus sp. RHA1

Site:
position = -40
score = 5.43269
sequence = TTGTGACAGCCATCACAA

Gene: RHA1_ro02831: Acetaldehyde dehydrogenase (EC 1.2.1.10)
Acetaldehyde dehydrogenase (EC 1.2.1.10)
adhB
 
Nocardia farcinica IFM 10152

Gene: nfa20970: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
 
Rhodococcus erythropolis PR4
 
Rhodococcus opacus B4

Gene: ROP_25560: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
 
Rhodococcus sp. RHA1

Gene: RHA1_ro02832: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
 
CRON 7.
whiB
*
Nocardia farcinica IFM 10152

Site:
position = -106
score = 6.25815
sequence = TCGTGAAAGCATTCACAA

Gene: nfa45800: WhiB-family transcriptional regulator involved in differentiation and sporulation
*
Rhodococcus erythropolis PR4

Site:
position = -106
score = 6.25815
sequence = TCGTGAAAGCATTCACAA

Gene: RER_21900: WhiB-family transcriptional regulator involved in differentiation and sporulation
*
Rhodococcus opacus B4

Site:
position = -103
score = 6.25815
sequence = TCGTGAAAGCATTCACAA

Gene: ROP_64060: WhiB-family transcriptional regulator involved in differentiation and sporulation
*
Rhodococcus sp. RHA1

Site:
position = -103
score = 6.25815
sequence = TCGTGAAAGCATTCACAA

Gene: RHA1_ro06345: WhiB-family transcriptional regulator involved in differentiation and sporulation
WhiB-family transcriptional regulator involved in differentiation and sporulation
 
CRON 8.
nuoA
 
Nocardia farcinica IFM 10152

Gene: nfa26670: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27270: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
*
Rhodococcus opacus B4

Site:
position = -88
score = 3.94661
sequence = CTGTGGCATAACTCACAA

Gene: ROP_59710: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
*
Rhodococcus sp. RHA1

Site:
position = -88
score = 3.94661
sequence = CTGTGGCATAACTCACAA

Gene: RHA1_ro05909: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
nuoB
 
Nocardia farcinica IFM 10152

Gene: nfa26660: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27260: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59720: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05910: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
nuoC
 
Nocardia farcinica IFM 10152

Gene: nfa26650: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27250: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59730: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05911: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
nuoD
 
Nocardia farcinica IFM 10152

Gene: nfa26640: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27240: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59740: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05912: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
nuoE
 
Nocardia farcinica IFM 10152

Gene: nfa26630: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27230: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59750: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05913: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
nuoF
 
Nocardia farcinica IFM 10152

Gene: nfa26620: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27220: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59760: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05914: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
nuoG
 
Nocardia farcinica IFM 10152

Gene: nfa26610: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27210: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59770: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05915: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
nuoH
 
Nocardia farcinica IFM 10152

Gene: nfa26600: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27200: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59780: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05916: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
nuoI
 
Nocardia farcinica IFM 10152
 
Rhodococcus erythropolis PR4

Gene: RER_27190: NADH-quinone oxidoreductase chain I
 
Rhodococcus opacus B4

Gene: ROP_59790: NADH-quinone oxidoreductase chain I
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05917: NADH-quinone oxidoreductase chain I
NADH-quinone oxidoreductase chain I
nuoJ
 
Nocardia farcinica IFM 10152

Gene: nfa26590: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27180: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59800: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05918: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
nuoK
 
Nocardia farcinica IFM 10152

Gene: nfa26580: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27170: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59810: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05919: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
nuoL
 
Nocardia farcinica IFM 10152

Gene: nfa26570: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27160: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59820: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05920: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
nuoM
 
Nocardia farcinica IFM 10152

Gene: nfa26560: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27150: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59830: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05921: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
nuoN
 
Nocardia farcinica IFM 10152

Gene: nfa26550: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
 
Rhodococcus erythropolis PR4

Gene: RER_27140: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
 
Rhodococcus opacus B4

Gene: ROP_59840: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
 
Rhodococcus sp. RHA1

Gene: RHA1_ro05922: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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