Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog BioQ - Mycobacteriaceae

Properties
Regulator type: Transcription factor
Regulator family: TetR
Regulation mode: repressor
Biological process: Biotin biosynthesis
Effector: Biotin
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 16 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Mycobacterium abscessus ATCC 19977 6 3
Mycobacterium avium 104
Mycobacterium flavescens PYR-GCK 6 3
Mycobacterium leprae TN
Mycobacterium marinum M
Mycobacterium smegmatis str. MC2 155 6 3
Mycobacterium sp. JLS 6 3
Mycobacterium tuberculosis H37Rv
Mycobacterium vanbaalenii PYR-1 6 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
bioB
*
Mycobacterium abscessus ATCC 19977

Site:
position = -54
score = 5.74163
sequence = CCTGAACACCGTTCAGG

Gene: MAB_2684c: Biotin synthase (EC 2.8.1.6)
 
Mycobacterium avium 104

Gene: MAV_3196: Biotin synthase (EC 2.8.1.6)
*
Mycobacterium flavescens PYR-GCK

Site:
position = -61
score = 5.85867
sequence = CCTGAACGGTGTTCAAG

Gene: Mflv_3624: Biotin synthase (EC 2.8.1.6)
 
Mycobacterium leprae TN

Gene: ML1220: Biotin synthase (EC 2.8.1.6)
 
Mycobacterium marinum M

Gene: MMAR_2387: Biotin synthase (EC 2.8.1.6)
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -52
score = 5.85867
sequence = CCTGAACACCGTTCAAG

Site:
position = -32
score = 5.43635
sequence = CCTGAACACCGTTCAGC

Gene: MSMEG_3194: Biotin synthase (EC 2.8.1.6)
*
Mycobacterium sp. JLS

Site:
position = -110
score = 5.85867
sequence = CCTGAACGGTGTTCAAT

Gene: Mjls_3090: Biotin synthase (EC 2.8.1.6)
 
Mycobacterium tuberculosis H37Rv

Gene: Rv1589: Biotin synthase (EC 2.8.1.6)
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -62
score = 5.85867
sequence = CCTGAACGGTGTTCAAT

Gene: Mvan_2793: Biotin synthase (EC 2.8.1.6)
Biotin synthase (EC 2.8.1.6)
MAB_2683c
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_2683c: hypothetical protein
 
Mycobacterium avium 104

Gene: MAV_3195: hypothetical protein
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_3623: hypothetical protein
 
Mycobacterium leprae TN

Gene: ML1221: hypothetical protein
 
Mycobacterium marinum M

Gene: MMAR_5574: hypothetical protein
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_3195: hypothetical protein
 
Mycobacterium sp. JLS

Gene: Mjls_3089: hypothetical protein
 
Mycobacterium tuberculosis H37Rv

Gene: Rv1590: hypothetical protein
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2794: hypothetical protein
hypothetical protein
MAB_2682c
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_2682c: hypothetical protein Rv1591
 
Mycobacterium avium 104

Gene: MAV_3193: hypothetical protein Rv1591
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_3622: hypothetical protein Rv1591
 
Mycobacterium leprae TN

Gene: ML1222: hypothetical protein Rv1591
 
Mycobacterium marinum M

Gene: MMAR_2388: hypothetical protein Rv1591
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_3196: hypothetical protein Rv1591
 
Mycobacterium sp. JLS

Gene: Mjls_3088: hypothetical protein Rv1591
 
Mycobacterium tuberculosis H37Rv

Gene: Rv1591: hypothetical protein Rv1591
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2795: hypothetical protein Rv1591
hypothetical protein Rv1591
 
CRON 2.
bioF
*
Mycobacterium abscessus ATCC 19977

Site:
position = -24
score = 6.1646
sequence = CCTGAACACCGTTCAGG

Gene: MAB_2687c: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
 
Mycobacterium avium 104

Gene: MAV_3205: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
*
Mycobacterium flavescens PYR-GCK

Site:
position = -43
score = 6.073
sequence = CCTGAACGGTGTTCAAG

Gene: Mflv_3628: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
 
Mycobacterium leprae TN

Gene: ML1217: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
 
Mycobacterium marinum M

Gene: MMAR_2384: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -133
score = 5.88342
sequence = CCTGAACGGTGTTCAAT

Gene: MSMEG_3189: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
*
Mycobacterium sp. JLS

Site:
position = -43
score = 5.88342
sequence = CCTGAACGGTGTTCAAT

Gene: Mjls_3094: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
 
Mycobacterium tuberculosis H37Rv

Gene: Rv1569: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -109
score = 5.42218
sequence = CCTGAACGGTGTTTAAT

Gene: Mvan_2789: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)
8-amino-7-oxononanoate synthase (EC 2.3.1.47)
bioD
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_2686c: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium avium 104

Gene: MAV_3204: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_3627: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium leprae TN

Gene: ML1218: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium marinum M

Gene: MMAR_2385: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_3190: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium sp. JLS

Gene: Mjls_3093: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium tuberculosis H37Rv

Gene: Rv1570: Dethiobiotin synthetase (EC 6.3.3.3)
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2790: Dethiobiotin synthetase (EC 6.3.3.3)
Dethiobiotin synthetase (EC 6.3.3.3)
 
CRON 3.
bioQ
*
Mycobacterium abscessus ATCC 19977

Site:
position = -24
score = 6.1646
sequence = CCTGAACGGTGTTCAGG

Gene: MAB_2685: Biotin repressor, TetR family
 
Mycobacterium avium 104
*
Mycobacterium flavescens PYR-GCK

Site:
position = -30
score = 6.073
sequence = CTTGAACACCGTTCAGG

Gene: Mflv_3625: Biotin repressor, TetR family
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -30
score = 6.073
sequence = CTTGAACGGTGTTCAGG

Gene: MSMEG_3193: Biotin repressor, TetR family
*
Mycobacterium sp. JLS

Site:
position = -30
score = 5.88342
sequence = ATTGAACACCGTTCAGG

Gene: Mjls_3091: Biotin repressor, TetR family
 
Mycobacterium tuberculosis H37Rv
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -30
score = 5.88342
sequence = ATTGAACACCGTTCAGG

Gene: Mvan_2792: Biotin repressor, TetR family
Biotin repressor, TetR family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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