Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog ThiR - Halobacteriales

Properties
Regulator type: Transcription factor
Regulator family: [Other]
Regulation mode: repressor
Biological process: Thiamine transport; Thiamine biosynthesis
Effector: Thiamine phosphate
Phylum: Euryarchaeota
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 40 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Haloarcula marismortui ATCC 43049 6 4
Halobacterium salinarum R1 3 2
Halobacterium sp. NRC-1 3 2
Haloferax volcanii DS2 2 2
Halomicrobium mukohataei DSM 12286 2 2
Haloquadratum walsbyi DSM 16790 3 2
Halorhabdus utahensis DSM 12940 5 3
Halorubrum lacusprofundi ATCC 49239 1 1
Haloterrigena turkmenica DSM 5511 2 2
Natrialba magadii ATCC 43099 3 3
Natronomonas pharaonis DSM 2160 4 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
thi4
*
Haloarcula marismortui ATCC 43049

Site:
position = 2
score = 4.67383
sequence = GTACCACCAAGAGATAT

Gene: rrnAC1782: Thiazole biosynthetic enzyme Thi4
*
Halobacterium salinarum R1

Site:
position = -28
score = 4.22469
sequence = TAATTATCTAGTTGTAC

Site:
position = -15
score = 4.6386
sequence = GTACCATGTAGTGGTAT

Gene: OE4651F: Thiazole biosynthetic enzyme Thi4
*
Halobacterium sp. NRC-1

Site:
position = -28
score = 4.22469
sequence = TAATTATCTAGTTGTAC

Site:
position = -15
score = 4.6386
sequence = GTACCATGTAGTGGTAT

Gene: VNG2604Gm: Thiazole biosynthetic enzyme Thi4
*
Haloferax volcanii DS2

Site:
position = -28
score = 5.0469
sequence = TTACTACTAGGTAGTAT

Site:
position = -15
score = 5.28335
sequence = GTATCACTAAGTAGTAT

Gene: HVO_0665: Thiazole biosynthetic enzyme Thi4
*
Halomicrobium mukohataei DSM 12286

Site:
position = -15
score = 5.29479
sequence = GTACCACTAGGTTGTAT

Gene: Hmuk_0002: Thiazole biosynthetic enzyme Thi4
*
Haloquadratum walsbyi DSM 16790

Site:
position = -15
score = 4.82031
sequence = ATAACACCAAGTAATAT

Gene: HQ1276A: Thiazole biosynthetic enzyme Thi4
*
Halorhabdus utahensis DSM 12940

Site:
position = -15
score = 5.37323
sequence = GTACCACTAAGTGGTAT

Gene: Huta_2718: Thiazole biosynthetic enzyme Thi4
*
Halorubrum lacusprofundi ATCC 49239

Site:
position = -28
score = 4.24518
sequence = GTACCACCGGGAGATAT

Site:
position = -15
score = 5.45364
sequence = ATATCACTAAGTGGTAT

Gene: Hlac_2980: Thiazole biosynthetic enzyme Thi4
*
Haloterrigena turkmenica DSM 5511

Site:
position = -15
score = 5.0629
sequence = CTACCACCAAGTTGTAT

Gene: Htur_1462: Thiazole biosynthetic enzyme Thi4
*
Natrialba magadii ATCC 43099

Site:
position = -15
score = 5.39728
sequence = ATACCACCTAGTTGTAT

Gene: Nmag_2419: Thiazole biosynthetic enzyme Thi4
*
Natronomonas pharaonis DSM 2160

Site:
position = -15
score = 5.10342
sequence = ATATAACTGAGTTGTAT

Gene: NP5174A: Thiazole biosynthetic enzyme Thi4
Thiazole biosynthetic enzyme Thi4
thiDN
 
Haloarcula marismortui ATCC 43049
 
Halobacterium salinarum R1

Gene: OE4654F: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
 
Halobacterium sp. NRC-1

Gene: VNG2606G: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
 
Haloferax volcanii DS2
 
Halomicrobium mukohataei DSM 12286
 
Haloquadratum walsbyi DSM 16790
 
Halorhabdus utahensis DSM 12940
 
Halorubrum lacusprofundi ATCC 49239
 
Haloterrigena turkmenica DSM 5511
 
Natrialba magadii ATCC 43099
 
Natronomonas pharaonis DSM 2160
Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
 
CRON 2.
thiC
*
Haloarcula marismortui ATCC 43049

Site:
position = -29
score = 5.09262
sequence = TTATAACTTGGTAGTAT

Site:
position = -16
score = 4.56026
sequence = GTATAACCTAGTGATTA

Gene: rrnAC1182: Thiamin biosynthesis protein ThiC
*
Halobacterium salinarum R1

Site:
position = -30
score = 4.80278
sequence = TTATTATCTAGTGGTAT

Site:
position = -17
score = 4.45129
sequence = GTATCACTAAGTAATTG

Gene: OE2057F: Thiamin biosynthesis protein ThiC
*
Halobacterium sp. NRC-1

Site:
position = -30
score = 4.80278
sequence = TTATTATCTAGTGGTAT

Site:
position = -17
score = 4.45129
sequence = GTATCACTAAGTAATTG

Gene: VNG0715G: Thiamin biosynthesis protein ThiC
*
Haloferax volcanii DS2

Site:
position = -30
score = 4.53047
sequence = TTATTAACTAGTTGTAT

Gene: HVO_2154: Thiamin biosynthesis protein ThiC
*
Halomicrobium mukohataei DSM 12286

Site:
position = -30
score = 4.8485
sequence = TTATAATCTAGTGATAT

Site:
position = -17
score = 4.31537
sequence = ATATAACTAGCTTATCT

Gene: Hmuk_2297: Thiamin biosynthesis protein ThiC
 
Haloquadratum walsbyi DSM 16790
*
Halorhabdus utahensis DSM 12940

Site:
position = -43
score = 5.25063
sequence = GTATCACTAGGTTATAT

Site:
position = -30
score = 4.91507
sequence = ATATAATCTAGTAGTAC

Gene: Huta_2472: Thiamin biosynthesis protein ThiC
 
Halorubrum lacusprofundi ATCC 49239
*
Haloterrigena turkmenica DSM 5511

Site:
position = -17
score = 4.45043
sequence = ATACAACCTAGTTATCG

Site:
position = -30
score = 4.61058
sequence = ATATAACTCGATGATAC

Gene: Htur_1332: Thiamin biosynthesis protein ThiC
*
Natrialba magadii ATCC 43099

Site:
position = -17
score = 4.68232
sequence = ATACAACCTAGTTATCC

Site:
position = -30
score = 4.67821
sequence = TTATAATCTAGTAATAC

Gene: Nmag_2593: Thiamin biosynthesis protein ThiC
*
Natronomonas pharaonis DSM 2160

Site:
position = -17
score = 4.10509
sequence = GTATTACTAGATTGTTG

Site:
position = -30
score = 4.56683
sequence = TTATTAGCTGGTTGTAT

Gene: NP2210A: Thiamin biosynthesis protein ThiC
Thiamin biosynthesis protein ThiC
 
CRON 3.
tenA1
*
Haloarcula marismortui ATCC 43049

Site:
position = -59
score = 5.39728
sequence = ATACAACCAAGTTGTAT

Gene: rrnAC1765: Thiaminase II (EC 3.5.99.2)
 
Halobacterium salinarum R1
 
Halobacterium sp. NRC-1
 
Haloferax volcanii DS2

Gene: HVO_B0381: Thiaminase II (EC 3.5.99.2)
 
Halomicrobium mukohataei DSM 12286
*
Haloquadratum walsbyi DSM 16790

Site:
position = -61
score = 4.83599
sequence = GTATTAGTTAGTTGTAT

Gene: HQ2369A: Thiaminase II (EC 3.5.99.2)
*
Halorhabdus utahensis DSM 12940

Site:
position = -55
score = 4.91507
sequence = GTATAATTTGGTAGTAT

Site:
position = -42
score = 4.24892
sequence = GTATTAGTGAGTTATAA

Gene: Huta_0684: Thiaminase II (EC 3.5.99.2)
 
Halorubrum lacusprofundi ATCC 49239

Gene: Hlac_2987: Thiaminase II (EC 3.5.99.2)
 
Haloterrigena turkmenica DSM 5511

Gene: Htur_2707: Thiaminase II (EC 3.5.99.2)
*
Natrialba magadii ATCC 43099

Site:
position = -55
score = 4.10061
sequence = GTATAAGCAGATTATAG

Site:
position = -42
score = 4.44075
sequence = ATAGCACTAGCTTATAT

Gene: Nmag_0869: Thiaminase II (EC 3.5.99.2)
*
Natronomonas pharaonis DSM 2160

Site:
position = -41
score = 4.24518
sequence = GTACCACCCGGATATAT

Gene: NP4082A: Thiaminase II (EC 3.5.99.2)
Thiaminase II (EC 3.5.99.2)
tenA2
 
Haloarcula marismortui ATCC 43049

Gene: rrnAC1767: Thiaminase II (EC 3.5.99.2)
 
Halobacterium salinarum R1
 
Halobacterium sp. NRC-1
 
Haloferax volcanii DS2

Gene: HVO_B0380: Thiaminase II (EC 3.5.99.2)
 
Halomicrobium mukohataei DSM 12286
 
Haloquadratum walsbyi DSM 16790
 
Halorhabdus utahensis DSM 12940

Gene: Huta_0685: Thiaminase II (EC 3.5.99.2)
 
Halorubrum lacusprofundi ATCC 49239

Gene: Hlac_2986: Thiaminase II (EC 3.5.99.2)
 
Haloterrigena turkmenica DSM 5511
 
Natrialba magadii ATCC 43099
 
Natronomonas pharaonis DSM 2160

Gene: NP4080A: Thiaminase II (EC 3.5.99.2)
Thiaminase II (EC 3.5.99.2)
thiV
 
Haloarcula marismortui ATCC 43049

Gene: rrnAC1769: Predicted thiamin transporter ThiV, SSS family
 
Halobacterium salinarum R1
 
Halobacterium sp. NRC-1
 
Haloferax volcanii DS2

Gene: HVO_B0379: Predicted thiamin transporter ThiV, SSS family
 
Halomicrobium mukohataei DSM 12286
 
Haloquadratum walsbyi DSM 16790

Gene: HQ2370A: Predicted thiamin transporter ThiV, SSS family
 
Halorhabdus utahensis DSM 12940

Gene: Huta_0686: Predicted thiamin transporter ThiV, SSS family
 
Halorubrum lacusprofundi ATCC 49239
 
Haloterrigena turkmenica DSM 5511
 
Natrialba magadii ATCC 43099
 
Natronomonas pharaonis DSM 2160
Predicted thiamin transporter ThiV, SSS family
 
CRON 4.
thiR2
*
Haloarcula marismortui ATCC 43049

Site:
position = -77
score = 5.39728
sequence = ATACAACTTGGTTGTAT

Gene: rrnAC1764: Predicted thiamin repressor ThiR, Xre family
 
Halobacterium salinarum R1
 
Halobacterium sp. NRC-1
 
Haloferax volcanii DS2
 
Halomicrobium mukohataei DSM 12286

Gene: Hmuk_1352: Predicted thiamin repressor ThiR, Xre family
 
Haloquadratum walsbyi DSM 16790
 
Halorhabdus utahensis DSM 12940

Gene: Huta_2411: Predicted thiamin repressor ThiR, Xre family
 
Halorubrum lacusprofundi ATCC 49239
 
Haloterrigena turkmenica DSM 5511

Gene: Htur_2542: Predicted thiamin repressor ThiR, Xre family
 
Natrialba magadii ATCC 43099

Gene: Nmag_0434: Predicted thiamin repressor ThiR, Xre family
 
Natronomonas pharaonis DSM 2160
Predicted thiamin repressor ThiR, Xre family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes [ Tab delimited format ] DOWNLOAD
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