Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog LexA - Mycobacteriaceae

Properties
Regulator type: Transcription factor
Regulator family: LexA
Regulation mode: repressor
Biological process: SOS response
Effector: DNA damage
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 83 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Mycobacterium abscessus ATCC 19977 12 8
Mycobacterium avium 104 13 9
Mycobacterium flavescens PYR-GCK 10 8
Mycobacterium leprae TN 4 3
Mycobacterium marinum M 13 9
Mycobacterium smegmatis str. MC2 155 12 8
Mycobacterium sp. JLS 11 7
Mycobacterium tuberculosis H37Rv 15 11
Mycobacterium vanbaalenii PYR-1 11 7
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
lexA
*
Mycobacterium abscessus ATCC 19977

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Site:
position = -169
score = 5.48704
sequence = TCGATCATGTGTTCGA

Site:
position = -150
score = 5.07538
sequence = CCGAACATGTGATCGA

Gene: MAB_3038: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium avium 104

Site:
position = -287
score = 4.96858
sequence = TCGCTCGTGTGTTCGA

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Gene: MAV_3614: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium flavescens PYR-GCK

Site:
position = -128
score = 5.40398
sequence = TCGATCAGGTGTTCGA

Site:
position = -108
score = 5.07538
sequence = TAGAACATGTGATCGA

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Gene: Mflv_3956: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium leprae TN

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Site:
position = -232
score = 5.5281
sequence = TCGATCATATGTTCGA

Gene: ML1003: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium marinum M

Site:
position = -282
score = 5.08124
sequence = TCGCTCAAGTGTTCGA

Site:
position = -258
score = 5.16341
sequence = TCGCTCACGTGTTCGA

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Gene: MMAR_1992: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -217
score = 5.20447
sequence = TCGCTCACATGTTCGA

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Gene: MSMEG_2740: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium sp. JLS

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Site:
position = -139
score = 5.40398
sequence = TCGATCAGGTGTTCGA

Gene: Mjls_2157: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium tuberculosis H37Rv

Site:
position = -238
score = 4.9932
sequence = CCGAACATTTGATCGA

Site:
position = -105
score = 5.55883
sequence = TCGAACACATGTTTGA

Gene: Rv2720: SOS-response repressor and protease LexA (EC 3.4.21.88)
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -163
score = 5.03431
sequence = TAGAACACGTGATCGA

Site:
position = -48
score = 5.55883
sequence = TCGAACACATGTTTGA

Site:
position = -183
score = 5.40398
sequence = TCGATCAGGTGTTCGA

Gene: Mvan_2441: SOS-response repressor and protease LexA (EC 3.4.21.88)
SOS-response repressor and protease LexA (EC 3.4.21.88)
 
CRON 2.
recA
*
Mycobacterium abscessus ATCC 19977

Site:
position = -143
score = 5.23421
sequence = TCGAACAGATGTTCGC

Gene: MAB_3060c: Recombinase A
*
Mycobacterium avium 104

Site:
position = -123
score = 5.44306
sequence = TCGAACACCTGTTCGG

Gene: MAV_3627: Recombinase A
*
Mycobacterium flavescens PYR-GCK

Site:
position = -133
score = 5.19315
sequence = TCGAACACCTGTTCGT

Gene: Mflv_3975: Recombinase A
*
Mycobacterium leprae TN

Site:
position = -113
score = 5.48412
sequence = TCGAACAGATGTTCGG

Gene: ML0987: Recombinase A
*
Mycobacterium marinum M

Site:
position = -121
score = 5.48412
sequence = TCGAACAGATGTTCGG

Gene: MMAR_1977: Recombinase A
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -121
score = 5.19315
sequence = TCGAACAGGTGTTCGT

Gene: MSMEG_2723: Recombinase A
*
Mycobacterium sp. JLS

Site:
position = -138
score = 5.19315
sequence = TCGAACAGGTGTTCGT

Gene: Mjls_2134: Recombinase A
*
Mycobacterium tuberculosis H37Rv

Site:
position = -123
score = 5.44306
sequence = TCGAACAGGTGTTCGG

Gene: Rv2737c: Recombinase A
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -121
score = 5.19315
sequence = TCGAACACCTGTTCGT

Gene: Mvan_2420: Recombinase A
Recombinase A
recX
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_3059c: Regulatory protein RecX
 
Mycobacterium avium 104

Gene: MAV_3626: Regulatory protein RecX
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_3974: Regulatory protein RecX
 
Mycobacterium leprae TN

Gene: ML0988: Regulatory protein RecX
 
Mycobacterium marinum M

Gene: MMAR_1978: Regulatory protein RecX
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_2724: Regulatory protein RecX
 
Mycobacterium sp. JLS

Gene: Mjls_2135: Regulatory protein RecX
 
Mycobacterium tuberculosis H37Rv

Gene: Rv2736c: Regulatory protein RecX
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2421: Regulatory protein RecX
Regulatory protein RecX
 
CRON 3.
alkB
*
Mycobacterium abscessus ATCC 19977

Site:
position = -28
score = 5.46039
sequence = TCGAACGTATGTGCGA

Gene: MAB_1120c: DNA repair system specific for alkylated DNA
*
Mycobacterium avium 104

Site:
position = -29
score = 5.37733
sequence = TCGAACGGATGTGCGA

Gene: MAV_1124: DNA repair system specific for alkylated DNA
*
Mycobacterium flavescens PYR-GCK

Site:
position = -29
score = 5.33626
sequence = TCGAACGCCTGTGCGA

Gene: Mflv_1921: DNA repair system specific for alkylated DNA
*
Mycobacterium leprae TN

Site:
position = -8
score = 5.19659
sequence = TCGAACTGATGTGCGA

Gene: ML0190: DNA repair system specific for alkylated DNA
*
Mycobacterium marinum M

Site:
position = -8
score = 5.19659
sequence = TCGAACTGATGTGCGA

Gene: MMAR_4493: DNA repair system specific for alkylated DNA
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -29
score = 5.41932
sequence = TCGAACGTGTGTGCGA

Gene: MSMEG_5451: DNA repair system specific for alkylated DNA
*
Mycobacterium sp. JLS

Site:
position = -29
score = 5.37826
sequence = TCGAACGCGTGTGCGA

Gene: Mjls_4657: DNA repair system specific for alkylated DNA
*
Mycobacterium tuberculosis H37Rv

Site:
position = -8
score = 5.33715
sequence = TCGAACGAATGTGCGA

Gene: Rv1000c: DNA repair system specific for alkylated DNA
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -29
score = 5.33626
sequence = TCGAACGCCTGTGCGA

Gene: Mvan_4812: DNA repair system specific for alkylated DNA
DNA repair system specific for alkylated DNA
 
CRON 4.
dnaE2
*
Mycobacterium abscessus ATCC 19977

Site:
position = -73
score = 5.85561
sequence = TCGAACAAATGTTCGA

Gene: MAB_3703c: DNA polymerase III alpha subunit (EC 2.7.7.7)
*
Mycobacterium avium 104

Site:
position = -29
score = 5.47916
sequence = TCGAACATCAGTTCGA

Gene: MAV_4335: DNA polymerase III alpha subunit (EC 2.7.7.7)
*
Mycobacterium flavescens PYR-GCK

Site:
position = -64
score = 5.6599
sequence = TCGAACGGATGTTCGA

Gene: Mflv_4893: DNA polymerase III alpha subunit (EC 2.7.7.7)
 
Mycobacterium leprae TN
*
Mycobacterium marinum M

Site:
position = -28
score = 5.41259
sequence = TCGAACATATTTTCGA

Gene: MMAR_1158: DNA polymerase III alpha subunit (EC 2.7.7.7)
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -28
score = 5.89672
sequence = TCGAACACGTGTTCGA

Gene: MSMEG_1633: DNA polymerase III alpha subunit (EC 2.7.7.7)
*
Mycobacterium sp. JLS

Site:
position = -28
score = 5.66083
sequence = TCGAACGCGTGTTCGA

Gene: Mjls_1210: DNA polymerase III alpha subunit (EC 2.7.7.7)
*
Mycobacterium tuberculosis H37Rv

Site:
position = -29
score = 5.73238
sequence = TCGAACAATTGTTCGA

Gene: Rv3370c: DNA polymerase III alpha subunit (EC 2.7.7.7)
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -28
score = 5.57866
sequence = TCGAACGCTTGTTCGA

Gene: Mvan_1530: DNA polymerase III alpha subunit (EC 2.7.7.7)
DNA polymerase III alpha subunit (EC 2.7.7.7)
 
CRON 5.
Rv3395c
*
Mycobacterium abscessus ATCC 19977

Site:
position = -41
score = 5.56718
sequence = TCGAACATATGTTCTA

Gene: MAB_3713c: Recombinase-like hypothetical protein
*
Mycobacterium avium 104

Site:
position = -52
score = 5.70189
sequence = TCGAACATGCGTTCGA

Gene: MAV_4346: Recombinase-like hypothetical protein
*
Mycobacterium flavescens PYR-GCK

Site:
position = -70
score = 4.87273
sequence = TCGAACAAAATTTCGA

Gene: Mflv_4899: Recombinase-like hypothetical protein
 
Mycobacterium leprae TN
*
Mycobacterium marinum M

Site:
position = -51
score = 5.1767
sequence = TCGAACATACTTTCGA

Gene: MMAR_1150: Recombinase-like hypothetical protein
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -52
score = 5.07302
sequence = TCGAACATACATTCGA

Gene: MSMEG_1620: Recombinase-like hypothetical protein
*
Mycobacterium sp. JLS

Site:
position = -52
score = 5.52116
sequence = TCGAACATGAGTTCGA

Gene: Mjls_1201: Recombinase-like hypothetical protein
*
Mycobacterium tuberculosis H37Rv

Site:
position = -30
score = 5.41259
sequence = TCGAACATATTTTCGA

Gene: Rv3395c: Recombinase-like hypothetical protein
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -52
score = 4.65906
sequence = TCGAACAAAGTTTCGA

Gene: Mvan_1522: Recombinase-like hypothetical protein
Recombinase-like hypothetical protein
COG0389
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_3712c: DNA polymerase-like protein PA0670
 
Mycobacterium avium 104

Gene: MAV_4344: DNA polymerase-like protein PA0670
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_4898: DNA polymerase-like protein PA0670
 
Mycobacterium leprae TN
 
Mycobacterium marinum M

Gene: MMAR_1151: DNA polymerase-like protein PA0670
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_1622: DNA polymerase-like protein PA0670
 
Mycobacterium sp. JLS

Gene: Mjls_1202: DNA polymerase-like protein PA0670
 
Mycobacterium tuberculosis H37Rv

Gene: Rv3394c: DNA polymerase-like protein PA0670
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_1523: DNA polymerase-like protein PA0670
DNA polymerase-like protein PA0670
 
CRON 6.
ruvC
*
Mycobacterium abscessus ATCC 19977

Site:
position = -82
score = 5.36089
sequence = TCGAACAACTGTTCTA

Gene: MAB_2884c: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
*
Mycobacterium avium 104

Site:
position = -33
score = 5.40106
sequence = TCGAACAGCTGTTCTA

Gene: MAV_3475: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_3826: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
 
Mycobacterium leprae TN

Gene: ML0481: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
*
Mycobacterium marinum M

Site:
position = -46
score = 5.32071
sequence = TCGAACAATTGTTCGG

Gene: MMAR_2109: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -30
score = 5.07246
sequence = TCGAACAGATGTTCTG

Gene: MSMEG_2943: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
*
Mycobacterium sp. JLS

Site:
position = -8
score = 4.78148
sequence = TCGAACAGGTGTTCTC

Gene: Mjls_2304: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
*
Mycobacterium tuberculosis H37Rv

Site:
position = -37
score = 5.08482
sequence = TCGAACGATTGTTCGG

Gene: Rv2594c: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -34
score = 5.07246
sequence = TCGAACAGATGTTCTG

Gene: Mvan_2573: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)
ruvA
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_2883c: Holliday junction DNA helicase RuvA
 
Mycobacterium avium 104

Gene: MAV_3474: Holliday junction DNA helicase RuvA
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_3825: Holliday junction DNA helicase RuvA
 
Mycobacterium leprae TN

Gene: ML0482: Holliday junction DNA helicase RuvA
 
Mycobacterium marinum M

Gene: MMAR_2110: Holliday junction DNA helicase RuvA
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_2944: Holliday junction DNA helicase RuvA
 
Mycobacterium sp. JLS

Gene: Mjls_2305: Holliday junction DNA helicase RuvA
 
Mycobacterium tuberculosis H37Rv

Gene: Rv2593c: Holliday junction DNA helicase RuvA
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2574: Holliday junction DNA helicase RuvA
Holliday junction DNA helicase RuvA
ruvB
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_2882c: Holliday junction DNA helicase RuvB
 
Mycobacterium avium 104

Gene: MAV_3473: Holliday junction DNA helicase RuvB
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_3824: Holliday junction DNA helicase RuvB
 
Mycobacterium leprae TN

Gene: ML0483: Holliday junction DNA helicase RuvB
 
Mycobacterium marinum M

Gene: MMAR_2111: Holliday junction DNA helicase RuvB
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_2945: Holliday junction DNA helicase RuvB
 
Mycobacterium sp. JLS

Gene: Mjls_2306: Holliday junction DNA helicase RuvB
 
Mycobacterium tuberculosis H37Rv

Gene: Rv2592c: Holliday junction DNA helicase RuvB
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2575: Holliday junction DNA helicase RuvB
Holliday junction DNA helicase RuvB
 
CRON 7.
Rv3074
 
Mycobacterium abscessus ATCC 19977
*
Mycobacterium avium 104

Site:
position = -23
score = 5.89672
sequence = TCGAACACGTGTTCGA

Gene: MAV_3980: Conserved hypothetical protein
 
Mycobacterium flavescens PYR-GCK
 
Mycobacterium leprae TN
*
Mycobacterium marinum M

Site:
position = -8
score = 5.93778
sequence = TCGAACACATGTTCGA

Gene: MMAR_1584: Conserved hypothetical protein
 
Mycobacterium smegmatis str. MC2 155
 
Mycobacterium sp. JLS
*
Mycobacterium tuberculosis H37Rv

Site:
position = -8
score = 5.93778
sequence = TCGAACACATGTTCGA

Gene: Rv3074: Conserved hypothetical protein
 
Mycobacterium vanbaalenii PYR-1
Conserved hypothetical protein
 
CRON 8.
PF02720
*
Mycobacterium abscessus ATCC 19977

Site:
position = -8
score = 5.32294
sequence = TCAAACGCATGTTCGA

Gene: MAB_4752: HNH endonuclease
 
Mycobacterium avium 104
*2
Mycobacterium flavescens PYR-GCK

Site:
position = 1
score = 5.27621
sequence = TGGAACACATGTTCGA

Gene: Mflv_3422: HNH endonuclease

Site:
position = -8
score = 5.93778
sequence = TCGAACACATGTTCGA

Gene: Mflv_4927: HNH endonuclease
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
*2
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_5583: HNH endonuclease

Site:
position = -8
score = 5.46039
sequence = TCGAACGTATGTGCGA

Gene: MSMEG_3957: HNH endonuclease
 
Mycobacterium sp. JLS
*2
Mycobacterium tuberculosis H37Rv

Site:
position = -8
score = 5.74296
sequence = TCGAACGTATGTTCGA

Gene: Rv3776: HNH endonuclease

Gene: Rv2100: HNH endonuclease
 
Mycobacterium vanbaalenii PYR-1
HNH endonuclease
 
CRON 9.
Rv0336
 
Mycobacterium abscessus ATCC 19977
*
Mycobacterium avium 104

Site:
position = -8
score = 5.69628
sequence = TCGAACATATGTGCGA

Gene: MAV_4456: Conserved hypothetical protein
 
Mycobacterium flavescens PYR-GCK
 
Mycobacterium leprae TN
*
Mycobacterium marinum M

Site:
position = -8
score = 5.07302
sequence = TCGAATGTATGTTCGA

Gene: MMAR_5187: Conserved hypothetical protein
 
Mycobacterium smegmatis str. MC2 155
 
Mycobacterium sp. JLS
*2
Mycobacterium tuberculosis H37Rv

Site:
position = -32
score = 5.1767
sequence = TCGAAAGTATGTTCGA

Gene: Rv0515: Conserved hypothetical protein

Site:
position = -32
score = 5.1767
sequence = TCGAAAGTATGTTCGA

Gene: Rv0336: Conserved hypothetical protein
 
Mycobacterium vanbaalenii PYR-1
Conserved hypothetical protein
 
CRON 10.
splB
*
Mycobacterium abscessus ATCC 19977

Site:
position = -24
score = 5.31727
sequence = TCGAACATATGTTCGC

Gene: MAB_2868c: DNA repair photolyase
*
Mycobacterium avium 104

Site:
position = -25
score = 5.4381
sequence = TCGAACTGGTGTTCGA

Gene: MAV_3456: DNA repair photolyase
*
Mycobacterium flavescens PYR-GCK

Site:
position = -23
score = 5.08138
sequence = TCGAACGTATGTTCGC

Gene: Mflv_3795: DNA repair photolyase
 
Mycobacterium leprae TN
*
Mycobacterium marinum M

Site:
position = -25
score = 5.39792
sequence = TCGAACTAGTGTTCGA

Gene: MMAR_2148: DNA repair photolyase
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -8
score = 5.70189
sequence = TCGAACGCATGTTCGA

Gene: MSMEG_2990: DNA repair photolyase
*
Mycobacterium sp. JLS

Site:
position = 35
score = 5.11267
sequence = TCGAACCTACGTTCGA

Gene: Mjls_2335: DNA repair photolyase
*
Mycobacterium tuberculosis H37Rv

Site:
position = -24
score = 5.125
sequence = TAGAACGGTTGTTCGA

Gene: Rv2578c: DNA repair photolyase
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -23
score = 5.08138
sequence = TCGAACGTATGTTCGC

Gene: Mvan_2599: DNA repair photolyase
DNA repair photolyase
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD