Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog BirA - Clostridia-3

Properties
Regulator type: Transcription factor
Regulator family: BirA
Regulation mode: repressor
Biological process: Biotin biosynthesis
Effector: Biotin
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 25 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Bacteroides pectinophilus ATCC 43243 2 2
Blautia hansenii DSM 20583 2 1
Bryantella formatexigens DSM 14469 2 1
Clostridiales bacterium 1_7_47_FAA 3 1
Clostridium bolteae ATCC BAA-613 4 1
Clostridium nexile DSM 1787 1 1
Clostridium scindens ATCC 35704 2 2
Dorea formicigenerans ATCC 27755 2 1
Dorea longicatena DSM 13814 4 3
Eubacterium eligens ATCC 27750 2 2
Eubacterium rectale ATCC 33656 2 2
Roseburia intestinalis L1-82 7 2
Ruminococcus gnavus ATCC 29149 2 2
Ruminococcus lactaris ATCC 29176 2 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
bioY
 
Bacteroides pectinophilus ATCC 43243
*
Blautia hansenii DSM 20583

Site:
position = -94
score = 8.86983
sequence = TTGTAAAC-(16)-GTTGACAA

Gene: BLAHAN_02475: Substrate-specific component BioY of biotin ECF transporter
*
Bryantella formatexigens DSM 14469

Site:
position = -154
score = 8.86983
sequence = TTGTAAAC-(16)-GTTGACAA

Site:
position = -96
score = 8.4065
sequence = ATGTAAAC-(16)-GTTTACAA

Gene: BRYFOR_01898: Substrate-specific component BioY of biotin ECF transporter
 
Clostridiales bacterium 1_7_47_FAA
 
Clostridium bolteae ATCC BAA-613
*
Clostridium nexile DSM 1787

Site:
position = -85
score = 8.98585
sequence = TTGTTAAC-(15)-GTTGACAA

Gene: CLONEX_00515: Substrate-specific component BioY of biotin ECF transporter
*
Clostridium scindens ATCC 35704

Site:
position = -142
score = 8.7149
sequence = TTGTTAAC-(15)-GTTGACAT

Gene: CLOSCI_02690: Substrate-specific component BioY of biotin ECF transporter
 
Dorea formicigenerans ATCC 27755

Gene: DORFOR_03063: Substrate-specific component BioY of biotin ECF transporter
*2
Dorea longicatena DSM 13814

Site:
position = -88
score = 8.86983
sequence = TTGTAAAC-(15)-GTTGACAA

Gene: DORLON_01236: Substrate-specific component BioY of biotin ECF transporter

Site:
position = -123
score = 8.7149
sequence = TTGTTAAC-(15)-GTTGACAT

Gene: DORLON_00987: Substrate-specific component BioY of biotin ECF transporter
*
Eubacterium eligens ATCC 27750

Site:
position = -95
score = 8.79125
sequence = ATGTCAAC-(15)-GTTGACAA

Gene: EUBELI_01172: Substrate-specific component BioY of biotin ECF transporter
*
Eubacterium rectale ATCC 33656

Site:
position = -104
score = 8.86983
sequence = TTGTAAAC-(16)-GTTGACAA

Gene: EUBREC_3289: Substrate-specific component BioY of biotin ECF transporter
*3
Roseburia intestinalis L1-82

Site:
position = -66
score = 8.86983
sequence = TTGTAAAC-(16)-GTTGACAA

Gene: ROSINTL182_00207: Substrate-specific component BioY of biotin ECF transporter

Site:
position = -86
score = 8.44394
sequence = ATGTTAAC-(16)-GTTGACAT

Site:
position = -33
score = 8.9095
sequence = TTGTTAAC-(16)-GTTAACAA

Gene: ROSINTL182_04738: Substrate-specific component BioY of biotin ECF transporter

Gene: ROSINTL182_04737: Substrate-specific component BioY of biotin ECF transporter
*
Ruminococcus gnavus ATCC 29149

Site:
position = -86
score = 8.7149
sequence = ATGTTAAC-(15)-GTTGACAA

Gene: RUMGNA_01549: Substrate-specific component BioY of biotin ECF transporter
*
Ruminococcus lactaris ATCC 29176

Site:
position = -102
score = 8.98585
sequence = TTGTTAAC-(15)-GTTGACAA

Gene: RUMLAC_01841: Substrate-specific component BioY of biotin ECF transporter
Substrate-specific component BioY of biotin ECF transporter
bioB
*
Bacteroides pectinophilus ATCC 43243

Site:
position = -154
score = 8.7149
sequence = TTGTCAAC-(15)-GTTAACAT

Gene: BACPEC_02754: Biotin synthase (EC 2.8.1.6)
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA
 
Clostridium bolteae ATCC BAA-613
 
Clostridium nexile DSM 1787
*
Clostridium scindens ATCC 35704

Site:
position = -85
score = 8.23167
sequence = CTGTAAAC-(15)-GTTGACAA

Gene: CLOSCI_01529: Biotin synthase (EC 2.8.1.6)
*
Dorea formicigenerans ATCC 27755

Site:
position = -110
score = 8.79125
sequence = TTGTCAAC-(16)-GTTGACAT

Gene: DORFOR_03064: Biotin synthase (EC 2.8.1.6)
*
Dorea longicatena DSM 13814

Site:
position = -65
score = 8.63854
sequence = ATGTTAAC-(15)-GTTAACAA

Gene: DORLON_02721: Biotin synthase (EC 2.8.1.6)
*
Eubacterium eligens ATCC 27750

Site:
position = -14
score = 8.5203
sequence = ATGTCAAC-(15)-GTTGACAT

Gene: EUBELI_20420: Biotin synthase (EC 2.8.1.6)
*
Eubacterium rectale ATCC 33656

Site:
position = -70
score = 8.98585
sequence = TTGTTAAC-(16)-GTTGACAA

Gene: EUBREC_0920: Biotin synthase (EC 2.8.1.6)
 
Roseburia intestinalis L1-82

Gene: ROSINTL182_04736: Biotin synthase (EC 2.8.1.6)
*
Ruminococcus gnavus ATCC 29149

Site:
position = -84
score = 8.67745
sequence = TTGTAAAC-(15)-GTTTACAA

Gene: RUMGNA_00689: Biotin synthase (EC 2.8.1.6)
*
Ruminococcus lactaris ATCC 29176

Site:
position = -135
score = 8.59888
sequence = ATGTAAAC-(16)-GTTGACAA

Gene: RUMLAC_00062: Biotin synthase (EC 2.8.1.6)
Biotin synthase (EC 2.8.1.6)
bioD
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA
 
Clostridium bolteae ATCC BAA-613
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814

Gene: DORLON_01235: Dethiobiotin synthetase (EC 6.3.3.3)
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82

Gene: ROSINTL182_04735: Dethiobiotin synthetase (EC 6.3.3.3)
 
Ruminococcus gnavus ATCC 29149
 
Ruminococcus lactaris ATCC 29176
Dethiobiotin synthetase (EC 6.3.3.3)
bioA
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583

Gene: BLAHAN_00622: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA
 
Clostridium bolteae ATCC BAA-613
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82

Gene: ROSINTL182_04734: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
 
Ruminococcus gnavus ATCC 29149

Gene: RUMGNA_01526: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
 
Ruminococcus lactaris ATCC 29176
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
PF06935
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583

Gene: BLAHAN_02474: Protein of unknown function DUF1284
 
Bryantella formatexigens DSM 14469

Gene: BRYFOR_01899: Protein of unknown function DUF1284
 
Clostridiales bacterium 1_7_47_FAA
 
Clostridium bolteae ATCC BAA-613
 
Clostridium nexile DSM 1787

Gene: CLONEX_02146: Protein of unknown function DUF1284
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82

Gene: ROSINTL182_00208: Protein of unknown function DUF1284
 
Ruminococcus gnavus ATCC 29149
 
Ruminococcus lactaris ATCC 29176
Protein of unknown function DUF1284
 
CRON 2.
SSF54637
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
*
Clostridiales bacterium 1_7_47_FAA

Site:
position = -97
score = 8.98585
sequence = TTGTTAAC-(15)-GTTGACAA

Gene: Cbac1_010100014191: Thioesterase/thiol ester dehydrase-isomerase
*
Clostridium bolteae ATCC BAA-613

Site:
position = -66
score = 8.98585
sequence = TTGTTAAC-(16)-GTTGACAA

Gene: CLOBOL_00883: Thioesterase/thiol ester dehydrase-isomerase
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149
 
Ruminococcus lactaris ATCC 29176
Thioesterase/thiol ester dehydrase-isomerase
bioY2
*
Bacteroides pectinophilus ATCC 43243

Site:
position = -142
score = 8.7149
sequence = ATGTTAAC-(15)-GTTGACAA

Gene: BACPEC_02755: Substrate-specific component BioY of biotin ECF transporter
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100014196: Substrate-specific component BioY of biotin ECF transporter
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_00884: Substrate-specific component BioY of biotin ECF transporter
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149
 
Ruminococcus lactaris ATCC 29176
Substrate-specific component BioY of biotin ECF transporter
yhfS
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100014201: Acetyl-CoA acetyltransferase (EC 2.3.1.9)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_00885: Acetyl-CoA acetyltransferase (EC 2.3.1.9)
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149
 
Ruminococcus lactaris ATCC 29176
Acetyl-CoA acetyltransferase (EC 2.3.1.9)
yhfT
 
Bacteroides pectinophilus ATCC 43243
 
Blautia hansenii DSM 20583
 
Bryantella formatexigens DSM 14469
 
Clostridiales bacterium 1_7_47_FAA

Gene: Cbac1_010100014211: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_00886: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Dorea formicigenerans ATCC 27755
 
Dorea longicatena DSM 13814
 
Eubacterium eligens ATCC 27750
 
Eubacterium rectale ATCC 33656
 
Roseburia intestinalis L1-82
 
Ruminococcus gnavus ATCC 29149
 
Ruminococcus lactaris ATCC 29176
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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