Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog Nur - Streptomycetaceae

Properties
Regulator type: Transcription factor
Regulator family: FUR
Regulation mode:
Biological process: Nickel homeostasis
Effector: Nickel ion, (Ni2+)
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 9 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Streptomyces avermitilis MA-4680 4 2
Streptomyces coelicolor A3(2) 9 3
Streptomyces griseus subsp. griseus NBRC 13350 6 2
Streptomyces scabiei 87.22 4 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
sodF
*
Streptomyces avermitilis MA-4680

Site:
position = -41
score = 5.7296
sequence = CTTGCAAGCACTTTGCAAT

Gene: SAV_5413: Superoxide dismutase [Fe-Zn] (EC 1.15.1.1), nickel-independent isozyme
*2
Streptomyces coelicolor A3(2)

Gene: SCO0999: Superoxide dismutase [Fe-Zn] (EC 1.15.1.1), nickel-independent isozyme

Site:
position = -41
score = 5.8332
sequence = GTTGCAAGGCTTTTGCAAT

Gene: SCO2633: Superoxide dismutase [Fe-Zn] (EC 1.15.1.1), nickel-independent isozyme
*
Streptomyces griseus subsp. griseus NBRC 13350

Site:
position = -60
score = 5.16149
sequence = CTTGCATATAGCTTGCAAT

Gene: SGR_4906: Superoxide dismutase [Fe-Zn] (EC 1.15.1.1), nickel-independent isozyme
*
Streptomyces scabiei 87.22

Site:
position = -40
score = 6.01064
sequence = GTTGCAAGTTCTTTGCAAC

Gene: SCAB_59731: Superoxide dismutase [Fe-Zn] (EC 1.15.1.1), nickel-independent isozyme
Superoxide dismutase [Fe-Zn] (EC 1.15.1.1), nickel-independent isozyme
 
CRON 2.
nikA
 
Streptomyces avermitilis MA-4680
*
Streptomyces coelicolor A3(2)

Site:
position = -51
score = 5.49401
sequence = ATTGCGAGTGATGTGCAAT

Gene: SCO6451: Nickel ABC transporter, periplasmic nickel-binding protein nikA2 (TC 3.A.1.5.3)
*
Streptomyces griseus subsp. griseus NBRC 13350

Site:
position = -51
score = 5.10475
sequence = ATTGCACACTGTTCGCAAT

Gene: SGR_498: Nickel ABC transporter, periplasmic nickel-binding protein nikA2 (TC 3.A.1.5.3)
 
Streptomyces scabiei 87.22
Nickel ABC transporter, periplasmic nickel-binding protein nikA2 (TC 3.A.1.5.3)
nikB
 
Streptomyces avermitilis MA-4680
 
Streptomyces coelicolor A3(2)

Gene: SCO6452: Nickel ABC transporter, inner membrane component nikB
 
Streptomyces griseus subsp. griseus NBRC 13350

Gene: SGR_497: Nickel ABC transporter, inner membrane component nikB
 
Streptomyces scabiei 87.22
Nickel ABC transporter, inner membrane component nikB
nikC
 
Streptomyces avermitilis MA-4680
 
Streptomyces coelicolor A3(2)

Gene: SCO6453: Nickel ABC transporter, inner membrane component nikC
 
Streptomyces griseus subsp. griseus NBRC 13350

Gene: SGR_496: Nickel ABC transporter, inner membrane component nikC
 
Streptomyces scabiei 87.22
Nickel ABC transporter, inner membrane component nikC
nikD
 
Streptomyces avermitilis MA-4680
 
Streptomyces coelicolor A3(2)

Gene: SCO6454: Nickel ABC transporter, ATP-binding protein component nikD
 
Streptomyces griseus subsp. griseus NBRC 13350

Gene: SGR_495: Nickel ABC transporter, ATP-binding protein component nikD
 
Streptomyces scabiei 87.22
Nickel ABC transporter, ATP-binding protein component nikD
nikE
 
Streptomyces avermitilis MA-4680
 
Streptomyces coelicolor A3(2)

Gene: SCO6455: Nickel ABC transporter, ATP-binding protein component nikE
 
Streptomyces griseus subsp. griseus NBRC 13350

Gene: SGR_494: Nickel ABC transporter, ATP-binding protein component nikE
 
Streptomyces scabiei 87.22
Nickel ABC transporter, ATP-binding protein component nikE
 
CRON 3.
nikMN
*
Streptomyces avermitilis MA-4680

Site:
position = -38
score = 5.84197
sequence = CTTGCAAGGCATTCGCAAC

Gene: SAV_3606: Substrate-specific component NikM of nickel ECF transporter / Additional substrate-specific component NikN of nickel ECF transporter
*
Streptomyces coelicolor A3(2)

Site:
position = -38
score = 5.47467
sequence = CTTGCGAACGAGTTGCAAC

Gene: SCO3159: Substrate-specific component NikM of nickel ECF transporter / Additional substrate-specific component NikN of nickel ECF transporter
 
Streptomyces griseus subsp. griseus NBRC 13350

Gene: SGR_4321: Substrate-specific component NikM of nickel ECF transporter / Additional substrate-specific component NikN of nickel ECF transporter
*
Streptomyces scabiei 87.22

Site:
position = -77
score = 5.25476
sequence = CTTGCAACAGACTCGCAAG

Gene: SCAB_53361: Substrate-specific component NikM of nickel ECF transporter / Additional substrate-specific component NikN of nickel ECF transporter
Substrate-specific component NikM of nickel ECF transporter / Additional substrate-specific component NikN of nickel ECF transporter
nikiQ
 
Streptomyces avermitilis MA-4680

Gene: SAV_3607: Transmembrane component NikQ of energizing module of nickel ECF transporter
 
Streptomyces coelicolor A3(2)

Gene: SCO3160: Transmembrane component NikQ of energizing module of nickel ECF transporter
 
Streptomyces griseus subsp. griseus NBRC 13350

Gene: SGR_4322: Transmembrane component NikQ of energizing module of nickel ECF transporter
 
Streptomyces scabiei 87.22

Gene: SCAB_53371: Transmembrane component NikQ of energizing module of nickel ECF transporter
Transmembrane component NikQ of energizing module of nickel ECF transporter
nikO
 
Streptomyces avermitilis MA-4680

Gene: SAV_3608: ATPase component NikO of energizing module of nickel ECF transporter
 
Streptomyces coelicolor A3(2)

Gene: SCO3161: ATPase component NikO of energizing module of nickel ECF transporter
 
Streptomyces griseus subsp. griseus NBRC 13350

Gene: SGR_4323: ATPase component NikO of energizing module of nickel ECF transporter
 
Streptomyces scabiei 87.22

Gene: SCAB_53381: ATPase component NikO of energizing module of nickel ECF transporter
ATPase component NikO of energizing module of nickel ECF transporter
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD