Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog IolR - Mycobacteriaceae

Properties
Regulator type: Transcription factor
Regulator family: GntR/Others
Regulation mode:
Biological process: Inositol utilization
Effector:
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 13 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Mycobacterium abscessus ATCC 19977
Mycobacterium avium 104
Mycobacterium flavescens PYR-GCK 9 3
Mycobacterium leprae TN
Mycobacterium marinum M
Mycobacterium smegmatis str. MC2 155 7 3
Mycobacterium sp. JLS
Mycobacterium tuberculosis H37Rv
Mycobacterium vanbaalenii PYR-1 9 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
iolC
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
*
Mycobacterium flavescens PYR-GCK

Site:
position = -88
score = 5.36767
sequence = AGAATGTCAGGACAAAGT

Gene: Mflv_2602: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -105
score = 3.71282
sequence = ACAAAGTCTTGACAGACG

Site:
position = -116
score = 5.08361
sequence = AGAATGTCAGAACAAAGT

Gene: MSMEG_4661: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -80
score = 3.77544
sequence = ACAAAGTCTTGACATGGC

Site:
position = -91
score = 5.36767
sequence = AGAATGTCAGGACAAAGT

Gene: Mvan_4016: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)
5-keto-2-deoxygluconokinase (EC 2.7.1.92)
iolJ
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_2601: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_4662: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_4017: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
iolB
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_2600: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_4663: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_4018: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)
5-deoxy-glucuronate isomerase (EC 5.3.1.-)
iolD
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_2599: Epi-inositol hydrolase (EC 3.7.1.-)
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_4664: Epi-inositol hydrolase (EC 3.7.1.-)
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_4019: Epi-inositol hydrolase (EC 3.7.1.-)
Epi-inositol hydrolase (EC 3.7.1.-)
iolG
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_2598: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_4666: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
 2
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_0387: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)

Gene: Mvan_4020: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)
Myo-inositol 2-dehydrogenase (EC 1.1.1.18)
 
CRON 2.
iolTA
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
*
Mycobacterium flavescens PYR-GCK

Site:
position = -129
score = 5.28157
sequence = CTAATGTCAGGACAAACT

Gene: Mflv_2605: Inositol ABC transport system sugar-binding protein
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -122
score = 4.83628
sequence = CTAATGTCATAACAAAGT

Gene: MSMEG_4658: Inositol ABC transport system sugar-binding protein
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -130
score = 5.17908
sequence = CTAATGTCAGGACAAAGT

Gene: Mvan_4011: Inositol ABC transport system sugar-binding protein
Inositol ABC transport system sugar-binding protein
iolTB
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_2606: Inositol ABC transport system permease protein
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_4657: Inositol ABC transport system permease protein
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_4010: Inositol ABC transport system permease protein
Inositol ABC transport system permease protein
iolTC
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_2607: Inositol ABC transport system ATP-binding protein
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_4656: Inositol ABC transport system ATP-binding protein
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_4009: Inositol ABC transport system ATP-binding protein
Inositol ABC transport system ATP-binding protein
 
CRON 3.
iolR
 
Mycobacterium abscessus ATCC 19977
 
Mycobacterium avium 104
*
Mycobacterium flavescens PYR-GCK

Site:
position = -84
score = 5.36767
sequence = ACTTTGTCCTGACATTCT

Gene: Mflv_2603: Inositol utilization transcriptional regulator, GntR family
 
Mycobacterium leprae TN
 
Mycobacterium marinum M
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -109
score = 3.71282
sequence = CGTCTGTCAAGACTTTGT

Site:
position = -98
score = 5.08361
sequence = ACTTTGTTCTGACATTCT

Gene: MSMEG_4659: Inositol utilization transcriptional regulator, GntR family
 
Mycobacterium sp. JLS
 
Mycobacterium tuberculosis H37Rv
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -98
score = 3.77544
sequence = GCCATGTCAAGACTTTGT

Site:
position = -87
score = 5.36767
sequence = ACTTTGTCCTGACATTCT

Gene: Mvan_4015: Inositol utilization transcriptional regulator, GntR family
Inositol utilization transcriptional regulator, GntR family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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