Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog MetR - Burkholderia

Properties
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Methionine biosynthesis
Effector: Homocysteine
Phylum: Proteobacteria/Beta
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 18 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Burkholderia pseudomallei K96243 2 2
Burkholderia mallei ATCC 23344 2 2
Burkholderia sp. 383 5 4
Burkholderia cepacia AMMD 2 2
Burkholderia vietnamiensis G4 2 2
Burkholderia glumae BGR1 4 4
Burkholderia xenovorans LB400
Burkholderia phymatum STM815 2 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
metR
*
Burkholderia pseudomallei K96243

Site:
position = -41
score = 4.94364
sequence = ATGAATTTTTTTCAA

Gene: BPSL2546: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Burkholderia mallei ATCC 23344

Site:
position = -41
score = 4.94364
sequence = ATGAATTTTTTTCAA

Gene: BMA0468: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Burkholderia sp. 383

Site:
position = 0
score = 5.04933
sequence = ATGGCATTATTTCAT

Gene: Bcep18194_B0361: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Burkholderia cepacia AMMD

Site:
position = -60
score = 5.04933
sequence = ATGGCATTATTTCAT

Gene: Bamb_4647: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Burkholderia vietnamiensis G4

Site:
position = 0
score = 5.04933
sequence = ATGGCATTATTTCAT

Gene: Bcep1808_3538: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*2
Burkholderia glumae BGR1

Site:
position = -75
score = 4.7563
sequence = ATGGATTGTTTTCAT

Gene: bglu_2g04940: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Site:
position = -40
score = 4.69335
sequence = ATGAAAAATATTCAG

Gene: bglu_1g08420: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
 
Burkholderia xenovorans LB400

Gene: Bxe_B1251: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Burkholderia phymatum STM815

Site:
position = -45
score = 5.26276
sequence = ATGGATTAATTTCAT

Gene: Bphy_5471: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
 
CRON 2.
PF08908
 
Burkholderia pseudomallei K96243
 
Burkholderia mallei ATCC 23344
*
Burkholderia sp. 383

Site:
position = -166
score = 4.65489
sequence = ATGAGATTAATTCAC

Gene: Bcep18194_C7370: Protein of unknown function DUF1852
 
Burkholderia cepacia AMMD
 
Burkholderia vietnamiensis G4
 
Burkholderia glumae BGR1
 
Burkholderia xenovorans LB400
 
Burkholderia phymatum STM815
Protein of unknown function DUF1852
metE2
 
Burkholderia pseudomallei K96243
 
Burkholderia mallei ATCC 23344
 
Burkholderia sp. 383

Gene: Bcep18194_C7369: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
 
Burkholderia cepacia AMMD
 
Burkholderia vietnamiensis G4
 
Burkholderia glumae BGR1
 
Burkholderia xenovorans LB400
 
Burkholderia phymatum STM815
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
 
CRON 3.
metE
*
Burkholderia pseudomallei K96243

Site:
position = -90
score = 4.94364
sequence = TTGAAAAAAATTCAT

Gene: BPSL2545: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Burkholderia mallei ATCC 23344

Site:
position = -90
score = 4.94364
sequence = TTGAAAAAAATTCAT

Gene: BMA0467: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Burkholderia sp. 383

Site:
position = -82
score = 5.04933
sequence = ATGAAATAATGCCAT

Gene: Bcep18194_B0362: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Burkholderia cepacia AMMD

Site:
position = -83
score = 5.04933
sequence = ATGAAATAATGCCAT

Gene: Bamb_4646: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Burkholderia vietnamiensis G4

Site:
position = -82
score = 5.04933
sequence = ATGAAATAATGCCAT

Gene: Bcep1808_3537: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*2
Burkholderia glumae BGR1

Site:
position = -106
score = 4.69335
sequence = CTGAATATTTTTCAT

Gene: bglu_1g08430: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Site:
position = -87
score = 4.7563
sequence = ATGAAAACAATCCAT

Gene: bglu_2g04930: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
 
Burkholderia xenovorans LB400
*
Burkholderia phymatum STM815

Site:
position = -81
score = 5.26276
sequence = ATGAAATTAATCCAT

Gene: Bphy_5470: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
 
CRON 4.
metR2
 
Burkholderia pseudomallei K96243
 
Burkholderia mallei ATCC 23344
*
Burkholderia sp. 383

Site:
position = -20
score = 4.88043
sequence = ATGAATTTTACTCAT

Gene: Bcep18194_C7372: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
 
Burkholderia cepacia AMMD
 
Burkholderia vietnamiensis G4
 
Burkholderia glumae BGR1
 
Burkholderia xenovorans LB400
 
Burkholderia phymatum STM815
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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