Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog MetR - Oceanospirillales/Alteromonadales

Properties
Regulator type: Transcription factor
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Methionine biosynthesis
Effector: Homocysteine
Phylum: Proteobacteria/Gamma
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 46 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Hahella chejuensis KCTC 2396 2 2
Marinobacter aqueolei 2 2
Marinobacter sp. ELB17 2 2
Oceanobacter sp. RED65 5 3
Oceanospirillum sp. MED92 3 2
Marinomonas sp. MWYL1 5 2
Saccharophagus degradans 2-40 2 2
Teredinibacter turnerae T7901 2 2
Cellvibrio japonicus Ueda107 2 2
Chromohalobacter salexigens DSM 3043 3 3
Reinekea sp. MED297 2 2
Alcanivorax borkumensis SK2 2 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
metE
*
Hahella chejuensis KCTC 2396

Site:
position = -91
score = 4.57699
sequence = ATGAATTTATTTAAT

Site:
position = -70
score = 4.50915
sequence = ATGAAATATTAACAT

Gene: HCH_01174: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Marinobacter aqueolei

Site:
position = -104
score = 4.61489
sequence = GTGAATCTTTTTCAT

Site:
position = -83
score = 4.05719
sequence = GTGAAATAATACCAT

Gene: Maqu_0809: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Marinobacter sp. ELB17

Site:
position = -67
score = 4.90154
sequence = GTGAATAGAATTCAT

Site:
position = -46
score = 4.06
sequence = GTGAAATAATACCAT

Gene: MELB17_19821: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
 
Oceanobacter sp. RED65
 
Oceanospirillum sp. MED92
 
Marinomonas sp. MWYL1
*
Saccharophagus degradans 2-40

Site:
position = -62
score = 4.20008
sequence = ATCAATTTTATTCAC

Site:
position = -93
score = 5.22028
sequence = ATGATTAAAATTCAT

Gene: Sde_0638: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Teredinibacter turnerae T7901

Site:
position = -81
score = 4.50915
sequence = ATGAAATAATACCAT

Site:
position = -102
score = 5.35351
sequence = ATGAATTGTATTCAT

Gene: TERTU_4688: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Cellvibrio japonicus Ueda107

Site:
position = -138
score = 4.65204
sequence = ATTAATTAAATTCAT

Gene: CJA_2448: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Chromohalobacter salexigens DSM 3043

Site:
position = -163
score = 4.29234
sequence = ATGAGTGCCGTTCAT

Gene: Csal_0672: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Reinekea sp. MED297

Site:
position = -102
score = 5.02378
sequence = ATGAATTTTACTCAT

Site:
position = -81
score = 4.58421
sequence = ATGAATTAATACCAT

Gene: MED297_11745: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
*
Alcanivorax borkumensis SK2

Site:
position = -230
score = 4.39374
sequence = ATGAATGCCTTTCCT

Site:
position = -147
score = 4.39751
sequence = TTGAGAAAAATTCAT

Gene: ABO_0861: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
 
CRON 2.
PF08908
 
Hahella chejuensis KCTC 2396
 
Marinobacter aqueolei
 
Marinobacter sp. ELB17
*
Oceanobacter sp. RED65

Site:
position = -86
score = 4.19905
sequence = ATGAGATAAAATCAA

Site:
position = -76
score = 4.57699
sequence = ATCAATTTTTTTCAT

Gene: RED65_13432: Protein of unknown function DUF1852
*
Oceanospirillum sp. MED92

Site:
position = -188
score = 4.37853
sequence = ATGAATAAATATAAT

Site:
position = -167
score = 4.72811
sequence = ATGAAAAGGTATCAT

Gene: MED92_05643: Protein of unknown function DUF1852
*
Marinomonas sp. MWYL1

Site:
position = -169
score = 5.41874
sequence = ATGAATAATATTCAT

Site:
position = -149
score = 4.02578
sequence = TTAAAATAAATTCAT

Gene: Mmwyl1_0387: Protein of unknown function DUF1852
 
Saccharophagus degradans 2-40
 
Teredinibacter turnerae T7901
 
Cellvibrio japonicus Ueda107
 
Chromohalobacter salexigens DSM 3043
 
Reinekea sp. MED297
 
Alcanivorax borkumensis SK2
Protein of unknown function DUF1852
metE2
 
Hahella chejuensis KCTC 2396
 
Marinobacter aqueolei
 
Marinobacter sp. ELB17
 
Oceanobacter sp. RED65

Gene: RED65_13427: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
 
Oceanospirillum sp. MED92

Gene: MED92_05638: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
 
Marinomonas sp. MWYL1

Gene: Mmwyl1_0388: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
 
Saccharophagus degradans 2-40
 
Teredinibacter turnerae T7901
 
Cellvibrio japonicus Ueda107
*
Chromohalobacter salexigens DSM 3043

Site:
position = -41
score = 4.75254
sequence = ATGAACGTCATTCAT

Gene: Csal_1563: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
 
Reinekea sp. MED297
 
Alcanivorax borkumensis SK2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
 
CRON 3.
metH
 
Hahella chejuensis KCTC 2396
 
Marinobacter aqueolei
 
Marinobacter sp. ELB17
*2
Oceanobacter sp. RED65

Gene: RED65_09024: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Site:
position = -106
score = 4.40734
sequence = ATGAGTAGTATTCAA

Gene: RED65_09029: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
*
Oceanospirillum sp. MED92

Site:
position = -129
score = 4.31029
sequence = ATGACCAATTTTCAT

Gene: MED92_04362: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Marinomonas sp. MWYL1

Gene: Mmwyl1_2169: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Saccharophagus degradans 2-40
 
Teredinibacter turnerae T7901
 
Cellvibrio japonicus Ueda107
 
Chromohalobacter salexigens DSM 3043
 
Reinekea sp. MED297
 
Alcanivorax borkumensis SK2
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
CRON 4.
glyA
 
Hahella chejuensis KCTC 2396
 
Marinobacter aqueolei
 
Marinobacter sp. ELB17
 
Oceanobacter sp. RED65
 
Oceanospirillum sp. MED92

Gene: MED92_08642: Serine hydroxymethyltransferase (EC 2.1.2.1)
*
Marinomonas sp. MWYL1

Site:
position = -95
score = 4.79334
sequence = ATGATCTTTTTTCAT

Gene: Mmwyl1_2283: Serine hydroxymethyltransferase (EC 2.1.2.1)
 
Saccharophagus degradans 2-40
 
Teredinibacter turnerae T7901
 
Cellvibrio japonicus Ueda107
 
Chromohalobacter salexigens DSM 3043
 
Reinekea sp. MED297
 
Alcanivorax borkumensis SK2
Serine hydroxymethyltransferase (EC 2.1.2.1)
gcvH
 
Hahella chejuensis KCTC 2396
 
Marinobacter aqueolei
 
Marinobacter sp. ELB17
 
Oceanobacter sp. RED65
 
Oceanospirillum sp. MED92

Gene: MED92_08647: Glycine cleavage system H protein
 
Marinomonas sp. MWYL1

Gene: Mmwyl1_2284: Glycine cleavage system H protein
 
Saccharophagus degradans 2-40
 
Teredinibacter turnerae T7901
 
Cellvibrio japonicus Ueda107
 
Chromohalobacter salexigens DSM 3043
 
Reinekea sp. MED297
 
Alcanivorax borkumensis SK2
Glycine cleavage system H protein
gcvP
 
Hahella chejuensis KCTC 2396
 
Marinobacter aqueolei
 
Marinobacter sp. ELB17
 
Oceanobacter sp. RED65
 
Oceanospirillum sp. MED92

Gene: MED92_08652: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2)
 
Marinomonas sp. MWYL1

Gene: Mmwyl1_2285: Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2)
 
Saccharophagus degradans 2-40
 
Teredinibacter turnerae T7901
 
Cellvibrio japonicus Ueda107
 
Chromohalobacter salexigens DSM 3043
 
Reinekea sp. MED297
 
Alcanivorax borkumensis SK2
Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2)
 
CRON 5.
metR
*
Hahella chejuensis KCTC 2396

Site:
position = -47
score = 4.50915
sequence = ATGTTAATATTTCAT

Site:
position = -26
score = 4.57699
sequence = ATTAAATAAATTCAT

Gene: HCH_01175: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Marinobacter aqueolei

Site:
position = -21
score = 4.05719
sequence = ATGGTATTATTTCAC

Site:
position = 0
score = 4.61489
sequence = ATGAAAAAGATTCAC

Gene: Maqu_0810: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Marinobacter sp. ELB17

Site:
position = -44
score = 4.90154
sequence = ATGAATTCTATTCAC

Site:
position = -65
score = 4.05719
sequence = ATGGTATTATTTCAC

Gene: MELB17_19816: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Oceanobacter sp. RED65

Site:
position = -29
score = 3.68523
sequence = CTGTATCTCATTCAT

Site:
position = -53
score = 3.61864
sequence = ATGAATATTCCTAAT

Gene: RED65_10519: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
 
Oceanospirillum sp. MED92

Gene: MED92_02289: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
 
Marinomonas sp. MWYL1

Gene: Mmwyl1_3390: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Saccharophagus degradans 2-40

Site:
position = -13
score = 5.22028
sequence = ATGAATTTTAATCAT

Site:
position = -44
score = 4.20008
sequence = GTGAATAAAATTGAT

Gene: Sde_0637: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Teredinibacter turnerae T7901

Site:
position = 0
score = 4.50915
sequence = ATGGTATTATTTCAT

Site:
position = 21
score = 5.35351
sequence = ATGAATACAATTCAT

Gene: TERTU_4689: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Cellvibrio japonicus Ueda107

Site:
position = -84
score = 4.65204
sequence = ATGAATTTAATTAAT

Site:
position = -115
score = 3.98024
sequence = ATGAATCAAACTGAT

Gene: CJA_2446: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Chromohalobacter salexigens DSM 3043

Site:
position = -20
score = 4.29234
sequence = ATGAACGGCACTCAT

Site:
position = -139
score = 3.8959
sequence = ATGAGTGACTTTCAG

Gene: Csal_0671: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Reinekea sp. MED297

Site:
position = -84
score = 4.58421
sequence = ATGGTATTAATTCAT

Site:
position = -63
score = 5.02378
sequence = ATGAGTAAAATTCAT

Gene: MED297_11750: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
*
Alcanivorax borkumensis SK2

Site:
position = -96
score = 4.39751
sequence = ATGAATTTTTCTCAA

Site:
position = -13
score = 4.39374
sequence = AGGAAAGGCATTCAT

Gene: ABO_0862: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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