Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog HTCS_Hep - Bacteroidaceae

Properties
Regulator type: Transcription factor
Regulator family: [Other]
Regulation mode: activator (repressor)
Biological process: Heparin utilization
Effector: Heparin
Phylum: Bacteroidetes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 10 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Bacteroides cellulosilyticus DSM 14838
Bacteroides coprophilus DSM 18228
Bacteroides dorei DSM 17855
Bacteroides eggerthii DSM 20697 4 2
Bacteroides fragilis NCTC 9343
Bacteroides ovatus ATCC 8483 12 3
Bacteroides plebeius DSM 17135
Bacteroides stercoris ATCC 43183 6 2
Bacteroides thetaiotaomicron VPI-5482 12 3
Bacteroides uniformis ATCC 8492
Bacteroides vulgatus ATCC 8482
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
hepC
 
Bacteroides cellulosilyticus DSM 14838

Gene: BACCELL_00780: Heparin lyase I / Heparinase I (EC 4.2.2.7)
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
*
Bacteroides eggerthii DSM 20697

Site:
position = -94
score = 8.41062
sequence = ACAAATATAG-(11)-ACAAATAGGA

Gene: BACEGG_00070: Heparin lyase I / Heparinase I (EC 4.2.2.7)
 
Bacteroides fragilis NCTC 9343
*
Bacteroides ovatus ATCC 8483

Site:
position = -92
score = 8.46113
sequence = ACAAATGTGA-(11)-ACAAAAGAAA

Gene: BACOVA_05497: Heparin lyase I / Heparinase I (EC 4.2.2.7)
 
Bacteroides plebeius DSM 17135
*
Bacteroides stercoris ATCC 43183

Site:
position = -96
score = 7.85472
sequence = ACAAATATAG-(11)-ACAAATAGGG

Gene: BACSTE_03699: Heparin lyase I / Heparinase I (EC 4.2.2.7)
*
Bacteroides thetaiotaomicron VPI-5482

Site:
position = -140
score = 8.30077
sequence = ACAAATGTGA-(11)-ACAAACGAAA

Gene: BT4675: Heparin lyase I / Heparinase I (EC 4.2.2.7)
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Heparin lyase I / Heparinase I (EC 4.2.2.7)
 
CRON 2.
hepL1
 
Bacteroides cellulosilyticus DSM 14838
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697
 
Bacteroides fragilis NCTC 9343
*
Bacteroides ovatus ATCC 8483

Site:
position = -148
score = 7.57771
sequence = ACATTATTAA-(11)-ACAATATTAA

Gene: BACOVA_05478: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
 
Bacteroides plebeius DSM 17135
*
Bacteroides stercoris ATCC 43183

Site:
position = -148
score = 8.69366
sequence = ACAAATACGA-(11)-ACAAATTTAA

Gene: BACSTE_03702: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
*
Bacteroides thetaiotaomicron VPI-5482

Site:
position = -149
score = 8.51968
sequence = ACAAAAACAA-(11)-ACAAATTTGA

Gene: BT4662: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
BT4661
 
Bacteroides cellulosilyticus DSM 14838
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
*
Bacteroides eggerthii DSM 20697

Site:
position = -153
score = 8.18803
sequence = ACAAATCTAA-(11)-ACAACTTTGA

Gene: BACEGG_00066: Hypothetical protein, presumably involved in heparin utilization
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05477: Hypothetical protein, presumably involved in heparin utilization
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03703: Hypothetical protein, presumably involved in heparin utilization
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4661: Hypothetical protein, presumably involved in heparin utilization
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Hypothetical protein, presumably involved in heparin utilization
susC_Hep-1
 
Bacteroides cellulosilyticus DSM 14838
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00065: TonB-dependent outer membrane transporter of heparin oligosaccharides
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05476: TonB-dependent outer membrane transporter of heparin oligosaccharides
 
Bacteroides plebeius DSM 17135
 2
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03705: TonB-dependent outer membrane transporter of heparin oligosaccharides

Gene: BACSTE_03704: TonB-dependent outer membrane transporter of heparin oligosaccharides
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4660: TonB-dependent outer membrane transporter of heparin oligosaccharides
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
TonB-dependent outer membrane transporter of heparin oligosaccharides
susD_Hep
 
Bacteroides cellulosilyticus DSM 14838
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00064: Outer membrane polysaccharide binding protein for heparin oligosaccharides
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05475: Outer membrane polysaccharide binding protein for heparin oligosaccharides
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03706: Outer membrane polysaccharide binding protein for heparin oligosaccharides
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4659: Outer membrane polysaccharide binding protein for heparin oligosaccharides
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Outer membrane polysaccharide binding protein for heparin oligosaccharides
 
CRON 3.
hepH
 
Bacteroides cellulosilyticus DSM 14838
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00062: Glucuronyl hydrolase ( 3.2.1.-)
 
Bacteroides fragilis NCTC 9343
*
Bacteroides ovatus ATCC 8483

Site:
position = -140
score = 8.42532
sequence = AGAAATTTAA-(11)-ACAAAATCAA

Gene: BACOVA_05474: Glucuronyl hydrolase ( 3.2.1.-)
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03707: Glucuronyl hydrolase ( 3.2.1.-)
*
Bacteroides thetaiotaomicron VPI-5482

Site:
position = -140
score = 7.99402
sequence = AGAATATTAA-(11)-ACAAATTCAA

Gene: BT4658: Glucuronyl hydrolase ( 3.2.1.-)
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Glucuronyl hydrolase ( 3.2.1.-)
hepL2
 
Bacteroides cellulosilyticus DSM 14838
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00061: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05473: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03708: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4657: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
nagS
 
Bacteroides cellulosilyticus DSM 14838
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00060: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05472: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03709: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4656: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)
nagX
 
Bacteroides cellulosilyticus DSM 14838

Gene: BACCELL_00769: Conserved hypothetical protein
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00059: Conserved hypothetical protein
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05471: Conserved hypothetical protein
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03710: Conserved hypothetical protein
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4655: Conserved hypothetical protein
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Conserved hypothetical protein
nagK
 
Bacteroides cellulosilyticus DSM 14838

Gene: BACCELL_00768: N-acetylglucosamine kinase (EC 2.7.1.59)
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00058: N-acetylglucosamine kinase (EC 2.7.1.59)
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05470: N-acetylglucosamine kinase (EC 2.7.1.59)
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03711: N-acetylglucosamine kinase (EC 2.7.1.59)
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4654: N-acetylglucosamine kinase (EC 2.7.1.59)
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
N-acetylglucosamine kinase (EC 2.7.1.59)
nagP
 
Bacteroides cellulosilyticus DSM 14838

Gene: BACCELL_00767: N-acetylglucosamine transporter
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697

Gene: BACEGG_00057: N-acetylglucosamine transporter
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05469: N-acetylglucosamine transporter
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183

Gene: BACSTE_03712: N-acetylglucosamine transporter
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4653: N-acetylglucosamine transporter
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
N-acetylglucosamine transporter
hepE
 
Bacteroides cellulosilyticus DSM 14838

Gene: BACCELL_00766: Predicted heparin lyase
 
Bacteroides coprophilus DSM 18228
 
Bacteroides dorei DSM 17855
 
Bacteroides eggerthii DSM 20697
 
Bacteroides fragilis NCTC 9343
 
Bacteroides ovatus ATCC 8483

Gene: BACOVA_05468: Predicted heparin lyase
 
Bacteroides plebeius DSM 17135
 
Bacteroides stercoris ATCC 43183
 
Bacteroides thetaiotaomicron VPI-5482

Gene: BT4652: Predicted heparin lyase
 
Bacteroides uniformis ATCC 8492
 
Bacteroides vulgatus ATCC 8482
Predicted heparin lyase
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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