Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog BirA - Lactobacillaceae

Properties
Regulator type: Transcription factor
Regulator family: BirA
Regulation mode: repressor
Biological process: Biotin biosynthesis
Effector: Biotin
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 10 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367
Lactobacillus casei ATCC 334
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956 2 1
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1 4 2
Lactobacillus reuteri JCM 1112 2 1
Lactobacillus rhamnosus GG
Lactobacillus sakei subsp. sakei 23K
Lactobacillus salivarius subsp. salivarius UCC118 1 1
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 4 2
Oenococcus oeni PSU-1 2 1
Pediococcus pentosaceus ATCC 25745 2 1
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
bioY
 
Lactobacillus acidophilus NCFM
 
Lactobacillus brevis ATCC 367

Gene: LVIS_0923: Substrate-specific component BioY of biotin ECF transporter
 
Lactobacillus casei ATCC 334

Gene: LSEI_2218: Substrate-specific component BioY of biotin ECF transporter
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
*
Lactobacillus fermentum IFO 3956

Site:
position = -54
score = 8.47466
sequence = ATTGTAACC-(16)-GGTTACAAA

Gene: LAF_0321: Substrate-specific component BioY of biotin ECF transporter
 
Lactobacillus helveticus DPC 4571

Gene: lhv_1920: Substrate-specific component BioY of biotin ECF transporter
 
Lactobacillus johnsonii NCC 533
*
Lactobacillus plantarum WCFS1

Site:
position = -76
score = 7.72647
sequence = ACAGTAACC-(16)-GGTTACTGT

Gene: lp_0336: Substrate-specific component BioY of biotin ECF transporter
*
Lactobacillus reuteri JCM 1112

Site:
position = -71
score = 8.69776
sequence = ATAGTAACC-(16)-GGTTACAAT

Gene: LAR_0704: Substrate-specific component BioY of biotin ECF transporter
 
Lactobacillus rhamnosus GG

Gene: LGG_02223: Substrate-specific component BioY of biotin ECF transporter
 
Lactobacillus sakei subsp. sakei 23K

Gene: LSA0825: Substrate-specific component BioY of biotin ECF transporter
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -91
score = 8.19175
sequence = ATTGTTAAC-(16)-GTTAACAAT

Gene: LSL_0074: Substrate-specific component BioY of biotin ECF transporter
*2
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Site:
position = -124
score = 7.58107
sequence = TTTGTTAAC-(16)-GGTAACATA

Gene: LEUM_0302: Substrate-specific component BioY of biotin ECF transporter

Site:
position = -45
score = 8.41961
sequence = TTAGTAAAC-(16)-GTTTACTAA

Gene: LEUM_0516: Substrate-specific component BioY of biotin ECF transporter
 
Oenococcus oeni PSU-1

Gene: OEOE_1597: Substrate-specific component BioY of biotin ECF transporter
*2
Pediococcus pentosaceus ATCC 25745

Site:
position = -81
score = 8.64298
sequence = ATAGTAACC-(16)-GGTTACTAT

Gene: PEPE_1637: Substrate-specific component BioY of biotin ECF transporter

Gene: PEPE_1592: Substrate-specific component BioY of biotin ECF transporter
Substrate-specific component BioY of biotin ECF transporter
yemC
 
Lactobacillus acidophilus NCFM
 
Lactobacillus brevis ATCC 367
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
 
Lactobacillus plantarum WCFS1

Gene: lp_0338: Zinc finger protein
 
Lactobacillus reuteri JCM 1112
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_0517: Zinc finger protein
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Zinc finger protein
birA
 
Lactobacillus acidophilus NCFM
 
Lactobacillus brevis ATCC 367
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_0322: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
 
Lactobacillus helveticus DPC 4571

Gene: lhv_1921: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
 
Lactobacillus johnsonii NCC 533
*2
Lactobacillus plantarum WCFS1

Gene: lp_0337: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)

Site:
position = -158
score = 7.66747
sequence = ATTGTACAC-(16)-GGTTACATT

Site:
position = -55
score = 8.08217
sequence = TTAGTTAAC-(16)-GTTAACTAA

Gene: lp_0854: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
 
Lactobacillus reuteri JCM 1112

Gene: LAR_0705: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118

Gene: LSL_0325: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
 2
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_0301: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)

Gene: LEUM_0518: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
*
Oenococcus oeni PSU-1

Site:
position = -48
score = 8.13696
sequence = TTAGTTAAC-(16)-GTTAACAAA

Gene: OEOE_1596: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
 
Pediococcus pentosaceus ATCC 25745

Gene: PEPE_1636: Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
Biotin biosynthesis repressor; Biotin-protein ligase (EC 6.3.4.15)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD