Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog LacR - Lactobacillaceae

Properties
Regulator type: Transcription factor
Regulator family: LacI
Regulation mode: repressor
Biological process: Lactose utilization
Effector: Lactose
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 11 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Lactobacillus acidophilus NCFM 1 1
Lactobacillus brevis ATCC 367
Lactobacillus casei ATCC 334
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956 3 2
Lactobacillus helveticus DPC 4571 1 1
Lactobacillus johnsonii NCC 533 3 2
Lactobacillus plantarum WCFS1 3 2
Lactobacillus reuteri JCM 1112 2 1
Lactobacillus rhamnosus GG
Lactobacillus sakei subsp. sakei 23K
Lactobacillus salivarius subsp. salivarius UCC118
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 3 2
Oenococcus oeni PSU-1
Pediococcus pentosaceus ATCC 25745
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
lacR
*
Lactobacillus acidophilus NCFM

Site:
position = -65
score = 4.66551
sequence = GGAATTGAGTAAATATT

Gene: LBA1465: Lactose utilization transcriptional regulator, LacI family
 
Lactobacillus brevis ATCC 367
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
*
Lactobacillus fermentum IFO 3956

Site:
position = -185
score = 5.49547
sequence = GTTAATTAGTAAATATT

Gene: LAF_0781: Lactose utilization transcriptional regulator, LacI family
*
Lactobacillus helveticus DPC 4571

Site:
position = -64
score = 5.29641
sequence = GGAATTTAGTAAATATT

Gene: lhv_1547: Lactose utilization transcriptional regulator, LacI family
*
Lactobacillus johnsonii NCC 533

Site:
position = -152
score = 4.54057
sequence = ATAATTTACTCAAAAAT

Gene: LJ0856: Lactose utilization transcriptional regulator, LacI family
*
Lactobacillus plantarum WCFS1

Site:
position = -155
score = 5.61286
sequence = AATAATTACTAAATATC

Gene: lp_3470: Lactose utilization transcriptional regulator, LacI family
 
Lactobacillus reuteri JCM 1112

Gene: LAR_1034: Lactose utilization transcriptional regulator, LacI family
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118
*
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Site:
position = -119
score = 5.35277
sequence = AAAAATTAGTAAATGAT

Gene: LEUM_1063: Lactose utilization transcriptional regulator, LacI family
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Lactose utilization transcriptional regulator, LacI family
 
CRON 2.
lacS
 
Lactobacillus acidophilus NCFM

Gene: LBA1463: Lactose and galactose permease, GPH translocator family
 
Lactobacillus brevis ATCC 367
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_0779: Lactose and galactose permease, GPH translocator family
 
Lactobacillus helveticus DPC 4571

Gene: lhv_1543: Lactose and galactose permease, GPH translocator family
*
Lactobacillus johnsonii NCC 533

Site:
position = -112
score = 5.49202
sequence = TATATTTAGTAAATTAT

Gene: LJ0857: Lactose and galactose permease, GPH translocator family
 
Lactobacillus plantarum WCFS1

Gene: lp_3468: Lactose and galactose permease, GPH translocator family
*
Lactobacillus reuteri JCM 1112

Site:
position = -79
score = 5.15585
sequence = AATATTTACTAAAATTA

Gene: LAR_1033: Lactose and galactose permease, GPH translocator family
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_1065: Lactose and galactose permease, GPH translocator family
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Lactose and galactose permease, GPH translocator family
lacZ
 
Lactobacillus acidophilus NCFM

Gene: LBA1462: Beta-galactosidase (EC 3.2.1.23)
 
Lactobacillus brevis ATCC 367
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
*
Lactobacillus fermentum IFO 3956

Site:
position = -112
score = 5.49547
sequence = AATATTTACTAATTAAC

Gene: LAF_0780: Beta-galactosidase (EC 3.2.1.23)
 
Lactobacillus helveticus DPC 4571

Gene: lhv_1542: Beta-galactosidase (EC 3.2.1.23)
 
Lactobacillus johnsonii NCC 533

Gene: LJ0858: Beta-galactosidase (EC 3.2.1.23)
*
Lactobacillus plantarum WCFS1

Site:
position = -108
score = 5.61286
sequence = GATATTTAGTAATTATT

Gene: lp_3469: Beta-galactosidase (EC 3.2.1.23)
 
Lactobacillus reuteri JCM 1112

Gene: LAR_1032: Beta-galactosidase (EC 3.2.1.23)
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118
*
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Site:
position = -110
score = 5.35277
sequence = ATCATTTACTAATTTTT

Gene: LEUM_1064: Beta-galactosidase (EC 3.2.1.23)
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Beta-galactosidase (EC 3.2.1.23)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD