Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog NrdR - Mycobacteriaceae

Properties
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Deoxyribonucleotide biosynthesis
Effector: Deoxyribonucleotides
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 43 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Mycobacterium abscessus ATCC 19977 4 2
Mycobacterium avium 104 4 2
Mycobacterium flavescens PYR-GCK 4 2
Mycobacterium leprae TN 4 2
Mycobacterium marinum M 4 2
Mycobacterium smegmatis str. MC2 155 4 4
Mycobacterium sp. JLS 4 2
Mycobacterium tuberculosis H37Rv 4 2
Mycobacterium vanbaalenii PYR-1 4 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
nrdF
*
Mycobacterium abscessus ATCC 19977

Site:
position = -73
score = 4.78439
sequence = CCCCTAGGGGTAGTGT

Site:
position = -105
score = 4.81863
sequence = CCACAACACGTTGTGT

Gene: MAB_3404c: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*
Mycobacterium avium 104

Site:
position = -96
score = 5.02514
sequence = ACACAACTTCTTGTGT

Site:
position = -64
score = 4.56096
sequence = ACCCCAGGGGTAGTGT

Gene: MAV_3913: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*
Mycobacterium flavescens PYR-GCK

Site:
position = -121
score = 4.91719
sequence = ACACAACATCTCGTAT

Site:
position = -89
score = 4.91308
sequence = ACACCAGTTGTAGTGT

Gene: Mflv_4286: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*
Mycobacterium leprae TN

Site:
position = -74
score = 4.02843
sequence = ACCCCAAGGGTAGTGT

Site:
position = -106
score = 4.98978
sequence = ACACTACTTCTTGTGT

Gene: ML1731: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*
Mycobacterium marinum M

Site:
position = -87
score = 4.80462
sequence = CCCCTACGGGTAGTGT

Site:
position = -119
score = 5.02514
sequence = ACACAACTTCTTGTGT

Gene: MMAR_1647: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*2
Mycobacterium smegmatis str. MC2 155

Site:
position = -110
score = 4.44677
sequence = CCACAACATCTCGGGG

Site:
position = -78
score = 4.98139
sequence = CCACCAGTTGTAGTGT

Gene: MSMEG_2313: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)

Site:
position = -78
score = 4.98139
sequence = CCACCAGTTGTAGTGT

Site:
position = -110
score = 4.44677
sequence = CCACAACATCTCGGGG

Gene: MSMEG_1033: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*
Mycobacterium sp. JLS

Site:
position = -89
score = 4.63725
sequence = ACACAACGAGTAGTGT

Site:
position = -121
score = 3.97897
sequence = ACCCAATATGTGGGGT

Gene: Mjls_1809: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*
Mycobacterium tuberculosis H37Rv

Site:
position = -95
score = 5.02514
sequence = ACACAACTTCTTGTGT

Site:
position = -63
score = 4.56096
sequence = ACCCCAGGGGTAGTGT

Gene: Rv3048c: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -77
score = 4.91308
sequence = ACACCAGTTGTAGTGT

Site:
position = -109
score = 4.95015
sequence = CCACTACATCTCGTAT

Gene: Mvan_2060: Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
 
CRON 2.
nrdH
*
Mycobacterium abscessus ATCC 19977

Site:
position = -188
score = 5.22332
sequence = ACACTAGGTGTAGTGT

Site:
position = -220
score = 4.91162
sequence = TCAGAACATCTTGTAT

Gene: MAB_3415c: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*
Mycobacterium avium 104

Site:
position = -264
score = 4.91162
sequence = TCAGAACATCTTGTAT

Site:
position = -249
score = 3.92042
sequence = TCTCGACATCTAGTGA

Site:
position = -232
score = 5.29164
sequence = CCACTAGGTGTAGTGT

Gene: MAV_3921: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*
Mycobacterium flavescens PYR-GCK

Site:
position = -204
score = 4.91162
sequence = TCAGAACATCTTGTAT

Site:
position = -172
score = 5.22332
sequence = ACACTAGGTGTAGTGT

Gene: Mflv_4307: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*
Mycobacterium leprae TN

Site:
position = -252
score = 4.91162
sequence = TCAGAACATCTTGTAT

Site:
position = -220
score = 5.29164
sequence = CCACTAGGTGTAGTGT

Gene: ML1736: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*
Mycobacterium marinum M

Site:
position = -269
score = 4.73764
sequence = TCCGAACATCTTGTAT

Site:
position = -237
score = 5.11766
sequence = CCCCTAGGTGTAGTGT

Gene: MMAR_1640: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*2
Mycobacterium smegmatis str. MC2 155

Site:
position = -261
score = 4.91162
sequence = TCAGAACATCTTGTAT

Site:
position = -229
score = 5.29164
sequence = CCACTAGGTGTAGTGT

Gene: MSMEG_1017: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib

Site:
position = -261
score = 4.91162
sequence = TCAGAACATCTTGTAT

Site:
position = -229
score = 5.29164
sequence = CCACTAGGTGTAGTGT

Gene: MSMEG_2297: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*
Mycobacterium sp. JLS

Site:
position = -260
score = 4.91162
sequence = TCAGAACATCTTGTAT

Site:
position = -228
score = 5.29164
sequence = CCACTAGGTGTAGTGT

Gene: Mjls_1796: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*
Mycobacterium tuberculosis H37Rv

Site:
position = -278
score = 4.91162
sequence = TCAGAACATCTTGTAT

Site:
position = -232
score = 5.11766
sequence = CCCCTAGGTGTAGTGT

Gene: Rv3053c: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -247
score = 4.57835
sequence = TCAGAACATCTTGTAG

Site:
position = -215
score = 5.22332
sequence = ACACTAGGTGTAGTGT

Site:
position = -182
score = 4.52647
sequence = CCCCAAGATGTAGGGG

Gene: Mvan_2040: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
nrdI
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_3414c: Ribonucleotide reduction protein NrdI
 
Mycobacterium avium 104

Gene: MAV_3920: Ribonucleotide reduction protein NrdI
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_4306: Ribonucleotide reduction protein NrdI
 
Mycobacterium leprae TN

Gene: ML1735: Ribonucleotide reduction protein NrdI
 
Mycobacterium marinum M

Gene: MMAR_1641: Ribonucleotide reduction protein NrdI
 
Mycobacterium smegmatis str. MC2 155
 
Mycobacterium sp. JLS

Gene: Mjls_1797: Ribonucleotide reduction protein NrdI
 
Mycobacterium tuberculosis H37Rv

Gene: Rv3052c: Ribonucleotide reduction protein NrdI
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2041: Ribonucleotide reduction protein NrdI
Ribonucleotide reduction protein NrdI
nrdE
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_3413c: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Mycobacterium avium 104

Gene: MAV_3919: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_4305: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Mycobacterium leprae TN

Gene: ML1734: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Mycobacterium marinum M

Gene: MMAR_1642: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 2
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_1019: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)

Gene: MSMEG_2299: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Mycobacterium sp. JLS

Gene: Mjls_1798: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
*
Mycobacterium tuberculosis H37Rv

Site:
position = -202
score = 3.83799
sequence = CCCGAAAATGTAGCGT

Gene: Rv3051c: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2042: Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
Ribonucleotide reductase of class Ib (aerobic), alpha subunit (EC 1.17.4.1)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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