Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog Rex - Thermoanaerobacterales

Properties
Regulator type: Transcription factor
Regulator family: Rex
Regulation mode: repressor
Biological process: Energy metabolism
Effector: NADH
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 42 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Caldicellulosiruptor saccharolyticus DSM 8903 22 6
Thermoanaerobacter tengcongensis MB4 33 13
Thermoanaerobacter ethanolicus X514 16 11
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
adhA2
*
Caldicellulosiruptor saccharolyticus DSM 8903

Site:
position = -46
score = 5.60024
sequence = ATGTTAAAATTATAACAA

Gene: Csac_0407: Alcohol dehydrogenase (EC 1.1.1.1), Fe-containing
 
Thermoanaerobacter tengcongensis MB4
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_1935: Alcohol dehydrogenase (EC 1.1.1.1), Fe-containing
Alcohol dehydrogenase (EC 1.1.1.1), Fe-containing
 
CRON 2.
hydC
*
Caldicellulosiruptor saccharolyticus DSM 8903

Site:
position = -38
score = 5.22386
sequence = ATGTTAAATTTCTAACAA

Gene: Csac_1860: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -82
score = 4.99253
sequence = ATGATATAATATTAACGA

Site:
position = -104
score = 5.21615
sequence = TTGTTAAAAAATTAATGA

Gene: TTE0890: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)
*
Thermoanaerobacter ethanolicus X514

Site:
position = -84
score = 4.64604
sequence = ATGATATAATATTGACGA

Site:
position = -106
score = 5.56654
sequence = TTGTTAAAAATTTAATAA

Gene: Teth514_2142: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)
NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2)
CLOLEP_03890
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1861: histidine kinase
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0891: histidine kinase
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_2141: histidine kinase
histidine kinase
hydD
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1862: NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0892: NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_2140: NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)
NAD-reducing Fe-hydrogenase, ferredoxin subunit HydD (EC 1.12.7.2)
hydB
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1863: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0893: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_2139: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)
NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2)
hydA
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1864: NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0894: NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_2138: NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)
NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2)
 
CRON 3.
echA
*
Caldicellulosiruptor saccharolyticus DSM 8903

Site:
position = -45
score = 5.03993
sequence = TTGTTAACAAATTAACTT

Gene: Csac_1534: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit A
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -144
score = 5.86399
sequence = TTGTTAAAATAATAACAA

Gene: TTE0123: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit A
 
Thermoanaerobacter ethanolicus X514
Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit A
echB
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1535: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit B
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0124: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit B
 
Thermoanaerobacter ethanolicus X514
Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit B
echC
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1536: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit C
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0125: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit C
 
Thermoanaerobacter ethanolicus X514
Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit C
echD
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1537: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit D
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0126: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit D
 
Thermoanaerobacter ethanolicus X514
Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit D
echE
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1538: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit E
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0127: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit E
 
Thermoanaerobacter ethanolicus X514
Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit E
echF
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1539: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit F
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0128: Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit F
 
Thermoanaerobacter ethanolicus X514
Energy-conserving Ni-Fe hydrogenase (ferredoxin), subunit F
hypA
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1540: [NiFe] hydrogenase nickel incorporation protein HypA
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0129: [NiFe] hydrogenase nickel incorporation protein HypA
 
Thermoanaerobacter ethanolicus X514
[NiFe] hydrogenase nickel incorporation protein HypA
hypB
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1541: [NiFe] hydrogenase nickel incorporation-associated protein HypB
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0130: [NiFe] hydrogenase nickel incorporation-associated protein HypB
 
Thermoanaerobacter ethanolicus X514
[NiFe] hydrogenase nickel incorporation-associated protein HypB
hypF
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1542: [NiFe] hydrogenase metallocenter assembly protein HypF
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0131: [NiFe] hydrogenase metallocenter assembly protein HypF
 
Thermoanaerobacter ethanolicus X514
[NiFe] hydrogenase metallocenter assembly protein HypF
hypC
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1543: [NiFe] hydrogenase metallocenter assembly protein HypC
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0132: [NiFe] hydrogenase metallocenter assembly protein HypC
 
Thermoanaerobacter ethanolicus X514
[NiFe] hydrogenase metallocenter assembly protein HypC
hypD
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1544: [NiFe] hydrogenase metallocenter assembly protein HypD
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0133: [NiFe] hydrogenase metallocenter assembly protein HypD
 
Thermoanaerobacter ethanolicus X514
[NiFe] hydrogenase metallocenter assembly protein HypD
hypE
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_1545: [NiFe] hydrogenase metallocenter assembly protein HypE
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0134: [NiFe] hydrogenase metallocenter assembly protein HypE
 
Thermoanaerobacter ethanolicus X514
[NiFe] hydrogenase metallocenter assembly protein HypE
 
CRON 4.
Csac_2425
*
Caldicellulosiruptor saccharolyticus DSM 8903

Site:
position = -187
score = 5.52146
sequence = ATGTTATAATATTAACAA

Gene: Csac_2425: hypothetical protein
 
Thermoanaerobacter tengcongensis MB4
 
Thermoanaerobacter ethanolicus X514
hypothetical protein
hydG
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_2424: [Fe] hydrogenase maturation protein HydG
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -93
score = 5.46442
sequence = TTGTTGAAAATTTAACAA

Gene: TTE1568: [Fe] hydrogenase maturation protein HydG
*
Thermoanaerobacter ethanolicus X514

Site:
position = -87
score = 5.52708
sequence = TTGTTGAAAAATTAACAA

Gene: Teth514_0530: [Fe] hydrogenase maturation protein HydG
[Fe] hydrogenase maturation protein HydG
 
CRON 5.
rex
*
Caldicellulosiruptor saccharolyticus DSM 8903

Site:
position = -39
score = 5.2201
sequence = ATGTCAAAAAAATATCAA

Gene: Csac_1220: Redox-sensitive transcriptional regulator Rex
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -60
score = 4.70833
sequence = TTGACAAGAAATTTACAA

Gene: TTE0543: Redox-sensitive transcriptional regulator Rex
*
Thermoanaerobacter ethanolicus X514

Site:
position = -59
score = 5.30617
sequence = TTGACAAAAAATTTACAA

Gene: Teth514_0496: Redox-sensitive transcriptional regulator Rex
Redox-sensitive transcriptional regulator Rex
 
CRON 6.
adhA
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -213
score = 5.19135
sequence = TTGATATAAATTTTACAA

Site:
position = -246
score = 5.22751
sequence = TTGATTATTTTTTAACAA

Gene: TTE0696: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent
*2
Thermoanaerobacter ethanolicus X514

Site:
position = -31
score = 5.19135
sequence = TTGATATAAATTTTACAA

Site:
position = -64
score = 5.22751
sequence = TTGATTATTTTTTAACAA

Gene: Teth514_0654: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent

Site:
position = -33
score = 5.72028
sequence = TTGTTATAAATTTAACAA

Gene: Teth514_0564: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent
Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent
 
CRON 7.
adhB
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -96
score = 5.15955
sequence = TTGACAAATTTTTAACTA

Site:
position = -63
score = 5.08198
sequence = TTGCAAAAAATTTAACAA

Gene: TTE0695: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
*
Thermoanaerobacter ethanolicus X514

Site:
position = -113
score = 5.38329
sequence = TTGATAAATTTTTAACTA

Site:
position = -80
score = 5.55872
sequence = TTGTAAAAAATTTAACAA

Gene: Teth514_0653: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent
 
CRON 8.
fnorB
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -116
score = 5.51272
sequence = TTGGTAAAAAAATAACAA

Gene: TTE0694: ferredoxin-NADP(+) reductase subunit beta
*
Thermoanaerobacter ethanolicus X514

Site:
position = -113
score = 5.28898
sequence = TTGGCAAAAAAATAACAA

Gene: Teth514_0652: ferredoxin-NADP(+) reductase subunit beta
ferredoxin-NADP(+) reductase subunit beta
fnorA
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0693: ferredoxin-NADP(+) reductase subunit alpha
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_0651: ferredoxin-NADP(+) reductase subunit alpha
ferredoxin-NADP(+) reductase subunit alpha
 
CRON 9.
TTE0622
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -73
score = 5.1963
sequence = TTGATAAATATTTGACAT

Gene: TTE0622: membrane spanning protein
*
Thermoanaerobacter ethanolicus X514

Site:
position = -74
score = 4.77146
sequence = TTGATATTTATTTGACAT

Gene: Teth514_0252: membrane spanning protein
membrane spanning protein
 
CRON 10.
COG4739
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -94
score = 5.54049
sequence = TTGATAAAATTTTATCAA

Gene: TTE2157: Ferredoxin domain containing protein
*
Thermoanaerobacter ethanolicus X514

Site:
position = -98
score = 5.54049
sequence = TTGATAAAATTTTATCAA

Gene: Teth514_0970: Ferredoxin domain containing protein
Ferredoxin domain containing protein
 
CRON 11.
noxE
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -107
score = 4.77374
sequence = TTGATATTTTATTGACAT

Site:
position = -158
score = 4.51657
sequence = TTGTCAACAAAAAATCAA

Gene: TTE1884: NADH oxidase (EC 1.6.99.3)
*
Thermoanaerobacter ethanolicus X514

Site:
position = -162
score = 5.01643
sequence = TTGTTAATAAAAAATCAA

Site:
position = -112
score = 4.77374
sequence = TTGATATTTTATTGACAT

Gene: Teth514_1131: NADH oxidase (EC 1.6.99.3)
NADH oxidase (EC 1.6.99.3)
 
CRON 12.
PF00724
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -35
score = 5.48061
sequence = CTGTTAATAAATTAACAA

Gene: TTE2131: NADH:flavin oxidoreductase
 
Thermoanaerobacter ethanolicus X514
NADH:flavin oxidoreductase
 
CRON 13.
bcd
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -33
score = 5.44384
sequence = ATGTTAAAAAAATATCAA

Gene: TTE0545: Butyryl-CoA dehydrogenase (EC 1.3.99.2)
 
Thermoanaerobacter ethanolicus X514
Butyryl-CoA dehydrogenase (EC 1.3.99.2)
etfB
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0546: Electron transfer flavoprotein, beta subunit
 
Thermoanaerobacter ethanolicus X514
Electron transfer flavoprotein, beta subunit
etfA
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0547: Electron transfer flavoprotein, alpha subunit
 
Thermoanaerobacter ethanolicus X514
Electron transfer flavoprotein, alpha subunit
hbd
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0548: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)
 
Thermoanaerobacter ethanolicus X514
3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)
acoA
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE0549: Acetyl-CoA acetyltransferase (EC 2.3.1.9)
 
Thermoanaerobacter ethanolicus X514
Acetyl-CoA acetyltransferase (EC 2.3.1.9)
 
CRON 14.
adhE
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Thermoanaerobacter tengcongensis MB4
*
Thermoanaerobacter ethanolicus X514

Site:
position = -151
score = 5.37205
sequence = TTGTTAAATGAATAACAA

Site:
position = -32
score = 5.39797
sequence = TTGTTAAATTATTAACAC

Gene: Teth514_0627: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10)
 
CRON 15.
ndh
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -58
score = 4.9885
sequence = ATGATAAAATATTGACTA

Site:
position = -34
score = 5.246
sequence = TTGTTATAATTATATCAA

Gene: TTE2486: NADH dehydrogenase (EC 1.6.99.3)
 
Thermoanaerobacter ethanolicus X514
NADH dehydrogenase (EC 1.6.99.3)
 
CRON 16.
adhA3
*
Caldicellulosiruptor saccharolyticus DSM 8903

Site:
position = -30
score = 5.05037
sequence = ATGTTAATTTTTTAACAG

Site:
position = -53
score = 4.73097
sequence = ATGTTTATATAATAATAA

Site:
position = -70
score = 4.81894
sequence = TTGACAAAAAACAAACAA

Gene: Csac_0622: Alcohol dehydrogenase (EC 1.1.1.1), iron-containing
 
Thermoanaerobacter tengcongensis MB4
 
Thermoanaerobacter ethanolicus X514
Alcohol dehydrogenase (EC 1.1.1.1), iron-containing
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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