Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog PerR - Lactobacillaceae

Properties
Regulator type: Transcription factor
Regulator family: FUR
Regulation mode: repressor
Biological process: Manganese homeostasis; Oxidative stress response; Iron homeostasis
Effector: Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 49 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367 7 6
Lactobacillus casei ATCC 334 7 5
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956 6 4
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1 8 6
Lactobacillus reuteri JCM 1112 6 4
Lactobacillus rhamnosus GG 6 4
Lactobacillus sakei subsp. sakei 23K 5 4
Lactobacillus salivarius subsp. salivarius UCC118 7 5
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Oenococcus oeni PSU-1
Pediococcus pentosaceus ATCC 25745 4 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
ahpC
 
Lactobacillus acidophilus NCFM
*
Lactobacillus brevis ATCC 367

Site:
position = -82
score = 4.91269
sequence = TTAGAATCATTCTTG

Gene: LVIS_0086: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
*
Lactobacillus casei ATCC 334

Site:
position = -31
score = 5.47394
sequence = TAATAATCATTCTAA

Gene: LSEI_2506: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
*
Lactobacillus fermentum IFO 3956

Site:
position = -32
score = 4.99081
sequence = TGATAATCGTTCTAA

Gene: LAF_0409: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
 
Lactobacillus plantarum WCFS1
*
Lactobacillus reuteri JCM 1112

Site:
position = -94
score = 5.58996
sequence = TTAGAATTGTTCTAA

Site:
position = -33
score = 5.67877
sequence = TAAGAATGATTCTAA

Gene: LAR_1019: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_1450: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
ahpF
 
Lactobacillus acidophilus NCFM
 
Lactobacillus brevis ATCC 367
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_0410: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
 
Lactobacillus plantarum WCFS1
 
Lactobacillus reuteri JCM 1112

Gene: LAR_1018: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_1451: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
 
CRON 2.
perR
 
Lactobacillus acidophilus NCFM
*
Lactobacillus brevis ATCC 367

Site:
position = -186
score = 5.45878
sequence = TTAGAATAATTCTTA

Gene: LVIS_1882: Peroxide stress response transcriptional regulator PerR, Fur family
 
Lactobacillus casei ATCC 334

Gene: LSEI_0869: Peroxide stress response transcriptional regulator PerR, Fur family
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
*
Lactobacillus fermentum IFO 3956

Site:
position = -27
score = 5.57219
sequence = TTAAAATGATTATAA

Gene: LAF_1362: Peroxide stress response transcriptional regulator PerR, Fur family
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
*
Lactobacillus plantarum WCFS1

Site:
position = -63
score = 4.80763
sequence = TTGGAATCCTTCTAA

Site:
position = -79
score = 4.96338
sequence = TAGTAATGTTTCTAA

Gene: lp_3247: Peroxide stress response transcriptional regulator PerR, Fur family
*
Lactobacillus reuteri JCM 1112

Site:
position = -107
score = 5.32397
sequence = TTAGAATAATTATTA

Site:
position = -31
score = 5.45302
sequence = TTATAATTATTTTAA

Gene: LAR_1232: Peroxide stress response transcriptional regulator PerR, Fur family
 
Lactobacillus rhamnosus GG

Gene: LGG_00831: Peroxide stress response transcriptional regulator PerR, Fur family
*
Lactobacillus sakei subsp. sakei 23K

Site:
position = -38
score = 4.66093
sequence = TGATAATGATTATCA

Gene: LSA0466: Peroxide stress response transcriptional regulator PerR, Fur family
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -33
score = 4.76458
sequence = TTATAAAAGTTATAA

Gene: LSL_1367: Peroxide stress response transcriptional regulator PerR, Fur family
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745

Gene: PEPE_0338: Peroxide stress response transcriptional regulator PerR, Fur family
Peroxide stress response transcriptional regulator PerR, Fur family
 
CRON 3.
pcl2
 
Lactobacillus acidophilus NCFM
*
Lactobacillus brevis ATCC 367

Site:
position = -98
score = 5.57065
sequence = TAAGAATTATTCTAA

Gene: LVIS_1881: Predicted membrane protein
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
*
Lactobacillus fermentum IFO 3956

Site:
position = -103
score = 5.3305
sequence = TTAGAATTCTTCTAA

Site:
position = -39
score = 5.72964
sequence = TTATAATGGTTCTAA

Gene: LAF_1546: Predicted membrane protein
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
*
Lactobacillus plantarum WCFS1

Site:
position = -37
score = 5.57552
sequence = TAATAATGATTATAA

Gene: lp_3360: Predicted membrane protein
*
Lactobacillus reuteri JCM 1112

Site:
position = -102
score = 5.42793
sequence = TTTTAATGATTCTAA

Site:
position = -38
score = 5.95331
sequence = TTATAATGATTCTAA

Gene: LAR_1418: Predicted membrane protein
 
Lactobacillus rhamnosus GG
*
Lactobacillus sakei subsp. sakei 23K

Site:
position = -43
score = 5.59483
sequence = TTATAATGGTTATAA

Gene: LSA1194: Predicted membrane protein
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -38
score = 5.49284
sequence = TTATAATTTTTCTAA

Gene: LSL_0409: Predicted membrane protein
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_0493: Predicted membrane protein
 2
Oenococcus oeni PSU-1

Gene: OEOE_1793: Predicted membrane protein

Gene: OEOE_0482: Predicted membrane protein
*
Pediococcus pentosaceus ATCC 25745

Site:
position = -37
score = 5.707
sequence = TTAAAATGATTCTAA

Gene: PEPE_0043: Predicted membrane protein
Predicted membrane protein
pcl1
 
Lactobacillus acidophilus NCFM
 
Lactobacillus brevis ATCC 367

Gene: LVIS_1880: Predicted membrane protein
 
Lactobacillus casei ATCC 334
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_1545: Predicted membrane protein
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
 
Lactobacillus plantarum WCFS1

Gene: lp_3359: Predicted membrane protein
 
Lactobacillus reuteri JCM 1112

Gene: LAR_1417: Predicted membrane protein
 
Lactobacillus rhamnosus GG
 
Lactobacillus sakei subsp. sakei 23K

Gene: LSA1195: Predicted membrane protein
 
Lactobacillus salivarius subsp. salivarius UCC118

Gene: LSL_0410: Predicted membrane protein
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_0494: Predicted membrane protein
 2
Oenococcus oeni PSU-1

Gene: OEOE_1792: Predicted membrane protein

Gene: OEOE_0481: Predicted membrane protein
 
Pediococcus pentosaceus ATCC 25745

Gene: PEPE_0044: Predicted membrane protein
Predicted membrane protein
 
CRON 4.
cueO
 
Lactobacillus acidophilus NCFM
 
Lactobacillus brevis ATCC 367

Gene: LVIS_0394: Predicted copper oxidase
*
Lactobacillus casei ATCC 334

Site:
position = -192
score = 5.31346
sequence = TTAGATTAATTCTAA

Gene: LSEI_2417: Predicted copper oxidase
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_1452: Predicted copper oxidase
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
*
Lactobacillus plantarum WCFS1

Site:
position = -88
score = 5.55771
sequence = TTAAAATAATTCTAA

Gene: lp_0355: Predicted copper oxidase
 
Lactobacillus reuteri JCM 1112
*
Lactobacillus rhamnosus GG

Site:
position = -72
score = 4.7726
sequence = TTAGATTAATTCCAA

Gene: LGG_02415: Predicted copper oxidase
 
Lactobacillus sakei subsp. sakei 23K
 
Lactobacillus salivarius subsp. salivarius UCC118
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_A31: Predicted copper oxidase
 
Oenococcus oeni PSU-1

Gene: OEOE_0009: Predicted copper oxidase
*
Pediococcus pentosaceus ATCC 25745

Site:
position = -73
score = 5.31346
sequence = TTAGATTAATTCTAA

Gene: PEPE_0502: Predicted copper oxidase
Predicted copper oxidase
ycnB
 
Lactobacillus acidophilus NCFM
*
Lactobacillus brevis ATCC 367

Site:
position = -39
score = 5.17713
sequence = TAAGAATATTTCTAA

Gene: LVIS_1917: Predicted permease
 
Lactobacillus casei ATCC 334

Gene: LSEI_2416: Predicted permease
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
*
Lactobacillus fermentum IFO 3956

Site:
position = -109
score = 5.32475
sequence = TTATAATCATTTTAA

Site:
position = -30
score = 4.81188
sequence = TTATAAGTTTTCTAA

Gene: LAF_1361: Predicted permease
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
 
Lactobacillus plantarum WCFS1

Gene: lp_3303: Predicted permease
*
Lactobacillus reuteri JCM 1112

Site:
position = -107
score = 5.4229
sequence = TTAAAATAATTATAA

Site:
position = -31
score = 5.60221
sequence = TAATAATTATTCTAA

Gene: LAR_1231: Predicted permease
 
Lactobacillus rhamnosus GG

Gene: LGG_02414: Predicted permease
 
Lactobacillus sakei subsp. sakei 23K
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -64
score = 4.56916
sequence = TTACAAAAATTCTAA

Gene: LSL_1578: Predicted permease
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_0546: Predicted permease
 
Oenococcus oeni PSU-1

Gene: OEOE_0192: Predicted permease
 
Pediococcus pentosaceus ATCC 25745

Gene: PEPE_0503: Predicted permease
Predicted permease
 
CRON 5.
cadA
 
Lactobacillus acidophilus NCFM

Gene: LBA1929: Predicted cation-transporting ATP-ase
*
Lactobacillus brevis ATCC 367

Site:
position = -52
score = 4.56277
sequence = CAATAATTGTTATAA

Gene: LVIS_0392: Predicted cation-transporting ATP-ase
*
Lactobacillus casei ATCC 334

Site:
position = -46
score = 5.20024
sequence = TTGTAATGGTTATAA

Site:
position = -80
score = 5.03426
sequence = TTATATTCGTTCTAA

Gene: LSEI_2799: Predicted cation-transporting ATP-ase
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365

Gene: LBUL_1992: Predicted cation-transporting ATP-ase
 
Lactobacillus fermentum IFO 3956
 
Lactobacillus helveticus DPC 4571

Gene: lhv_2064: Predicted cation-transporting ATP-ase
 
Lactobacillus johnsonii NCC 533

Gene: LJ1792: Predicted cation-transporting ATP-ase
*
Lactobacillus plantarum WCFS1

Site:
position = -93
score = 5.37168
sequence = TTAGAATCATTCTTA

Gene: lp_3327: Predicted cation-transporting ATP-ase
 
Lactobacillus reuteri JCM 1112

Gene: LAR_0171: Predicted cation-transporting ATP-ase
*
Lactobacillus rhamnosus GG

Site:
position = -80
score = 5.03426
sequence = TTATATTCGTTCTAA

Site:
position = -46
score = 5.20024
sequence = TTGTAATGGTTATAA

Gene: LGG_02803: Predicted cation-transporting ATP-ase
*
Lactobacillus sakei subsp. sakei 23K

Site:
position = -65
score = 5.30157
sequence = TGATAATAATTCTAA

Gene: LSA0969: Predicted cation-transporting ATP-ase
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -93
score = 5.49284
sequence = TTATAATTTTTCTAA

Gene: LSL_0169: Predicted cation-transporting ATP-ase
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745

Gene: PEPE_0090: Predicted cation-transporting ATP-ase
Predicted cation-transporting ATP-ase
 
CRON 6.
ybbL
 
Lactobacillus acidophilus NCFM

Gene: LBA1499: Predicted ABC transporter, ATP-binding protein
 
Lactobacillus brevis ATCC 367

Gene: LVIS_2102: Predicted ABC transporter, ATP-binding protein
*
Lactobacillus casei ATCC 334

Site:
position = -40
score = 5.78694
sequence = TTAGAATGATTATAA

Gene: LSEI_2588: Predicted ABC transporter, ATP-binding protein
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_1021: Predicted ABC transporter, ATP-binding protein
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533

Gene: LJ0728: Predicted ABC transporter, ATP-binding protein
*
Lactobacillus plantarum WCFS1

Site:
position = -36
score = 5.95331
sequence = TTATAATGATTCTAA

Gene: lp_3225: Predicted ABC transporter, ATP-binding protein
 
Lactobacillus reuteri JCM 1112
*
Lactobacillus rhamnosus GG

Site:
position = -35
score = 5.02241
sequence = TTAGAATGGTTACAA

Gene: LGG_02565: Predicted ABC transporter, ATP-binding protein
 
Lactobacillus sakei subsp. sakei 23K

Gene: LSA0979: Predicted ABC transporter, ATP-binding protein
*
Lactobacillus salivarius subsp. salivarius UCC118

Site:
position = -38
score = 5.49284
sequence = TTATAATTTTTCTAA

Gene: LSL_1684: Predicted ABC transporter, ATP-binding protein
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_A10: Predicted ABC transporter, ATP-binding protein
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Predicted ABC transporter, ATP-binding protein
ybbM
 
Lactobacillus acidophilus NCFM

Gene: LBA1500: Predicted ABC transporter, permease protein
 
Lactobacillus brevis ATCC 367

Gene: LVIS_2101: Predicted ABC transporter, permease protein
 
Lactobacillus casei ATCC 334

Gene: LSEI_2589: Predicted ABC transporter, permease protein
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365

Gene: LBUL_0029: Predicted ABC transporter, permease protein
 
Lactobacillus fermentum IFO 3956

Gene: LAF_1020: Predicted ABC transporter, permease protein
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533

Gene: LJ0729: Predicted ABC transporter, permease protein
 
Lactobacillus plantarum WCFS1

Gene: lp_3224: Predicted ABC transporter, permease protein
 
Lactobacillus reuteri JCM 1112
 
Lactobacillus rhamnosus GG

Gene: LGG_02566: Predicted ABC transporter, permease protein
 
Lactobacillus sakei subsp. sakei 23K

Gene: LSA0978: Predicted ABC transporter, permease protein
 
Lactobacillus salivarius subsp. salivarius UCC118

Gene: LSL_1683: Predicted ABC transporter, permease protein
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_A09: Predicted ABC transporter, permease protein
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745
Predicted ABC transporter, permease protein
 
CRON 7.
npr
 
Lactobacillus acidophilus NCFM

Gene: LBA1401: NADH peroxidase (EC 1.11.1.1)
*
Lactobacillus brevis ATCC 367

Site:
position = -90
score = 5.92175
sequence = TTAGAATGATTCTAA

Gene: LVIS_B09: NADH peroxidase (EC 1.11.1.1)
*
Lactobacillus casei ATCC 334

Site:
position = -74
score = 4.73808
sequence = TTGGAACTATTCTAA

Gene: LSEI_0397: NADH peroxidase (EC 1.11.1.1)
 
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
 
Lactobacillus fermentum IFO 3956

Gene: LAF_1460: NADH peroxidase (EC 1.11.1.1)
 
Lactobacillus helveticus DPC 4571
 
Lactobacillus johnsonii NCC 533
*2
Lactobacillus plantarum WCFS1

Site:
position = -95
score = 5.09679
sequence = TTAGAATAATTACAA

Gene: lp_2544: NADH peroxidase (EC 1.11.1.1)

Gene: lp_1445: NADH peroxidase (EC 1.11.1.1)
 
Lactobacillus reuteri JCM 1112
*
Lactobacillus rhamnosus GG

Site:
position = -75
score = 5.4506
sequence = TTGTAATTATTCTAA

Gene: LGG_00491: NADH peroxidase (EC 1.11.1.1)
*
Lactobacillus sakei subsp. sakei 23K

Site:
position = -61
score = 4.96094
sequence = TTGTAATAATTATTA

Gene: LSA0575: NADH peroxidase (EC 1.11.1.1)
 
Lactobacillus salivarius subsp. salivarius UCC118

Gene: LSL_0137: NADH peroxidase (EC 1.11.1.1)
 
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293

Gene: LEUM_0104: NADH peroxidase (EC 1.11.1.1)
 
Oenococcus oeni PSU-1
 
Pediococcus pentosaceus ATCC 25745

Gene: PEPE_1619: NADH peroxidase (EC 1.11.1.1)
NADH peroxidase (EC 1.11.1.1)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD