Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog SAM - Chloroflexia

Properties
Regulator type: RNA regulatory element
Name: SAM
RFAM: RF00162
Regulation mode:
Biological process: Methionine biosynthesis
Effector: S-adenosylmethionine
Phylum: Chloroflexi
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Chloroflexus aggregans DSM 9485 12 3
Chloroflexus sp. Y-400-fl 12 3
Roseiflexus castenholzii DSM 13941 3 2
Roseiflexus sp. RS-1 3 2
Herpetosiphon aurantiacus ATCC 23779 13 4
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
cysH
 
Chloroflexus aggregans DSM 9485
 
Chloroflexus sp. Y-400-fl
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_0330: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
 
Roseiflexus sp. RS-1

Gene: RoseRS_0739: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
*
Herpetosiphon aurantiacus ATCC 23779

Site:
position = -181
score = 73.4
sequence = GCACTCATCCAGAGG...

Gene: Haur_1749: Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10)
sat-cysC
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_1550: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_2278: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_4308: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25)
 
Roseiflexus sp. RS-1

Gene: RoseRS_3336: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25)
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_1748: Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4)
Sulfate adenylyltransferase, dissimilatory-type (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25)
cysC
 
Chloroflexus aggregans DSM 9485
 
Chloroflexus sp. Y-400-fl
 
Roseiflexus castenholzii DSM 13941
 
Roseiflexus sp. RS-1
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_1747: Adenylylsulfate kinase (EC 2.7.1.25)
Adenylylsulfate kinase (EC 2.7.1.25)
cysI
 
Chloroflexus aggregans DSM 9485
 
Chloroflexus sp. Y-400-fl
 
Roseiflexus castenholzii DSM 13941
 
Roseiflexus sp. RS-1
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_1746: Ferredoxin--sulfite reductase, bacillial type (EC 1.8.7.1)
Ferredoxin--sulfite reductase, bacillial type (EC 1.8.7.1)
 
CRON 2.
metI
*
Chloroflexus aggregans DSM 9485

Site:
position = -181
score = 69.53
sequence = GCACTCATCCAGAGC...

Gene: Cagg_1948: Cystathionine gamma-synthase (EC 2.5.1.48)
*
Chloroflexus sp. Y-400-fl

Site:
position = -182
score = 67.5
sequence = GCACTCATCCAGAGC...

Gene: Chy400_1581: Cystathionine gamma-synthase (EC 2.5.1.48)
 
Roseiflexus castenholzii DSM 13941
 
Roseiflexus sp. RS-1
 
Herpetosiphon aurantiacus ATCC 23779
Cystathionine gamma-synthase (EC 2.5.1.48)
metF
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_1947: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_1580: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_3006: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
 
Roseiflexus sp. RS-1

Gene: RoseRS_2032: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
 
Herpetosiphon aurantiacus ATCC 23779
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
map
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_1946: Methionine aminopeptidase (EC 3.4.11.18)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_1579: Methionine aminopeptidase (EC 3.4.11.18)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_1086: Methionine aminopeptidase (EC 3.4.11.18)
 
Roseiflexus sp. RS-1

Gene: RoseRS_3795: Methionine aminopeptidase (EC 3.4.11.18)
 2
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_1134: Methionine aminopeptidase (EC 3.4.11.18)

Gene: Haur_1133: Methionine aminopeptidase (EC 3.4.11.18)
Methionine aminopeptidase (EC 3.4.11.18)
Cagg_1945
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_1945: hypothetical protein
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_1578: hypothetical protein
 
Roseiflexus castenholzii DSM 13941
 
Roseiflexus sp. RS-1
 
Herpetosiphon aurantiacus ATCC 23779
hypothetical protein
 
CRON 3.
metH
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_0032: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_4231: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
*
Roseiflexus castenholzii DSM 13941

Site:
position = -237
score = 57.35
sequence = GCTCATCCAGAGGAG...

Gene: Rcas_3878: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
*
Roseiflexus sp. RS-1

Site:
position = -151
score = 62.39
sequence = GCTCATCCAGAGGAG...

Gene: RoseRS_0064: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
*
Herpetosiphon aurantiacus ATCC 23779

Site:
position = -203
score = 68.94
sequence = CCTCATCACGAGGAG...

Gene: Haur_2544: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
 
CRON 4.
mtnA
*
Chloroflexus aggregans DSM 9485

Site:
position = -135
score = 84.38
sequence = GCTCATCGAGATGGG...

Gene: Cagg_3560: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
*
Chloroflexus sp. Y-400-fl

Site:
position = -166
score = 84.11
sequence = ATGCTCATCGAGATG...

Gene: Chy400_3271: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_0156: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
 
Roseiflexus sp. RS-1

Gene: RoseRS_0485: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
*
Herpetosiphon aurantiacus ATCC 23779

Site:
position = -137
score = 88.24
sequence = TCTCATCGAGATGGG...

Gene: Haur_2349: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
Cagg_3561
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_3561: hypothetical protein
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_3270: hypothetical protein
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_0157: hypothetical protein
 
Roseiflexus sp. RS-1

Gene: RoseRS_0486: hypothetical protein
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_2350: hypothetical protein
hypothetical protein
adk
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_3562: putative Adenosine kinase (EC 2.7.1.20)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_3269: putative Adenosine kinase (EC 2.7.1.20)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_0158: putative Adenosine kinase (EC 2.7.1.20)
 
Roseiflexus sp. RS-1

Gene: RoseRS_0487: putative Adenosine kinase (EC 2.7.1.20)
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_2351: putative Adenosine kinase (EC 2.7.1.20)
putative Adenosine kinase (EC 2.7.1.20)
Cagg_3563
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_3563: oxidoreductase domain protein
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_3268: oxidoreductase domain protein
 
Roseiflexus castenholzii DSM 13941
 
Roseiflexus sp. RS-1
 
Herpetosiphon aurantiacus ATCC 23779
oxidoreductase domain protein
ahcY
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_3564: Adenosylhomocysteinase (EC 3.3.1.1)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_3267: Adenosylhomocysteinase (EC 3.3.1.1)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_0159: Adenosylhomocysteinase (EC 3.3.1.1)
 
Roseiflexus sp. RS-1

Gene: RoseRS_0488: Adenosylhomocysteinase (EC 3.3.1.1)
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_2352: Adenosylhomocysteinase (EC 3.3.1.1)
Adenosylhomocysteinase (EC 3.3.1.1)
metK
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_3565: S-adenosylmethionine synthetase (EC 2.5.1.6)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_3266: S-adenosylmethionine synthetase (EC 2.5.1.6)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_0160: S-adenosylmethionine synthetase (EC 2.5.1.6)
 
Roseiflexus sp. RS-1

Gene: RoseRS_0489: S-adenosylmethionine synthetase (EC 2.5.1.6)
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_2353: S-adenosylmethionine synthetase (EC 2.5.1.6)
S-adenosylmethionine synthetase (EC 2.5.1.6)
 
CRON 5.
metY
*
Chloroflexus aggregans DSM 9485

Site:
position = -215
score = 82.38
sequence = GCACTCATCCAGAGC...

Gene: Cagg_0970: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
*
Chloroflexus sp. Y-400-fl

Site:
position = -212
score = 80.03
sequence = ACTCATCCAGAGCGG...

Gene: Chy400_3740: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
*
Roseiflexus castenholzii DSM 13941

Site:
position = -403
score = 46.66
sequence = ACTCTTATCCAGAGA...

Gene: Rcas_2040: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
*
Roseiflexus sp. RS-1

Site:
position = -411
score = 42.47
sequence = TCTTATCCAGAGAGG...

Gene: RoseRS_1758: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
*
Herpetosiphon aurantiacus ATCC 23779

Site:
position = -256
score = 73.98
sequence = ACTCATCCAGAGGGG...

Gene: Haur_0927: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Haur_0928
 
Chloroflexus aggregans DSM 9485
 
Chloroflexus sp. Y-400-fl
 
Roseiflexus castenholzii DSM 13941
 
Roseiflexus sp. RS-1
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_0928: hypothetical protein
hypothetical protein
metX
 
Chloroflexus aggregans DSM 9485

Gene: Cagg_0969: Homoserine O-acetyltransferase (EC 2.3.1.31)
 
Chloroflexus sp. Y-400-fl

Gene: Chy400_3741: Homoserine O-acetyltransferase (EC 2.3.1.31)
 
Roseiflexus castenholzii DSM 13941

Gene: Rcas_2039: Homoserine O-acetyltransferase (EC 2.3.1.31)
 
Roseiflexus sp. RS-1

Gene: RoseRS_1759: Homoserine O-acetyltransferase (EC 2.3.1.31)
 
Herpetosiphon aurantiacus ATCC 23779

Gene: Haur_0929: Homoserine O-acetyltransferase (EC 2.3.1.31)
Homoserine O-acetyltransferase (EC 2.3.1.31)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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