Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog LldR - Corynebacteriaceae

Properties
Regulator type: Transcription factor
Regulator family: GntR/Others
Regulation mode: repressor
Biological process: Lactate utilization
Effector: L-lactate
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 12 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Corynebacterium amycolatum SK46
Corynebacterium aurimucosum ATCC 700975
Corynebacterium diphtheriae NCTC 13129 5 3
Corynebacterium efficiens YS-314 8 3
Corynebacterium glutamicum ATCC 13032 12 4
Corynebacterium jeikeium K411
Corynebacterium kroppenstedtii DSM 44385
Corynebacterium urealyticum DSM 7109
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
lldE
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_1042: Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE
*
Corynebacterium diphtheriae NCTC 13129

Site:
position = -332
score = 3.9019
sequence = TTTGGGTGGACCACA

Gene: DIP1032: Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE
 
Corynebacterium efficiens YS-314
 
Corynebacterium glutamicum ATCC 13032
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_1293: Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE
 
Corynebacterium urealyticum DSM 7109
Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE
lldF
 
Corynebacterium amycolatum SK46

Gene: CORAM0001_0634: Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_1041: Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF
 
Corynebacterium diphtheriae NCTC 13129

Gene: DIP1031: Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF
 
Corynebacterium efficiens YS-314
 
Corynebacterium glutamicum ATCC 13032
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_1294: Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF
 
Corynebacterium urealyticum DSM 7109
Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF
lldG
 
Corynebacterium amycolatum SK46

Gene: CORAM0001_0633: Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_1040: Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG
 
Corynebacterium diphtheriae NCTC 13129

Gene: DIP1030: Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG
 
Corynebacterium efficiens YS-314
 
Corynebacterium glutamicum ATCC 13032
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_1295: Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG
 
Corynebacterium urealyticum DSM 7109
Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG
 
CRON 2.
ldhA
 
Corynebacterium amycolatum SK46

Gene: CORAM0001_2074: L-lactate dehydrogenase (EC 1.1.1.27)
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_2403: L-lactate dehydrogenase (EC 1.1.1.27)
 
Corynebacterium diphtheriae NCTC 13129

Gene: DIP2255: L-lactate dehydrogenase (EC 1.1.1.27)
*
Corynebacterium efficiens YS-314

Site:
position = -119
score = 4.82966
sequence = AGTGGTCCGGCCAGA

Gene: CE2753: L-lactate dehydrogenase (EC 1.1.1.27)
*
Corynebacterium glutamicum ATCC 13032

Site:
position = -137
score = 5.37601
sequence = CTTGGTCTGACCACA

Gene: cg3219: L-lactate dehydrogenase (EC 1.1.1.27)
 
Corynebacterium jeikeium K411

Gene: jk0113: L-lactate dehydrogenase (EC 1.1.1.27)
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_0111: L-lactate dehydrogenase (EC 1.1.1.27)
 
Corynebacterium urealyticum DSM 7109
L-lactate dehydrogenase (EC 1.1.1.27)
 
CRON 3.
cg3226
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975
 
Corynebacterium diphtheriae NCTC 13129
*
Corynebacterium efficiens YS-314

Site:
position = -14
score = 5.08265
sequence = CATGGCCTGACCACA

Site:
position = -27
score = 5.959
sequence = TGTGGTCTGACCACA

Gene: CE2761: L-lactate permease, PF00083 family
*
Corynebacterium glutamicum ATCC 13032

Site:
position = -77
score = 5.29164
sequence = TGTGGTCTGACCATG

Gene: cg3226: L-lactate permease, PF00083 family
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385
 
Corynebacterium urealyticum DSM 7109
L-lactate permease, PF00083 family
lldD
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_0795: L-lactate dehydrogenase (EC 1.1.2.3)
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE2762: L-lactate dehydrogenase (EC 1.1.2.3)
 
Corynebacterium glutamicum ATCC 13032

Gene: cg3227: L-lactate dehydrogenase (EC 1.1.2.3)
 
Corynebacterium jeikeium K411

Gene: jk1705: L-lactate dehydrogenase (EC 1.1.2.3)
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_0013: L-lactate dehydrogenase (EC 1.1.2.3)
 
Corynebacterium urealyticum DSM 7109
L-lactate dehydrogenase (EC 1.1.2.3)
 
CRON 4.
lldP
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_1046: L-lactate permease
*2
Corynebacterium diphtheriae NCTC 13129

Site:
position = -122
score = 5.37601
sequence = TGTGGTCTTACCACT

Site:
position = -108
score = 5.1022
sequence = TGTGGTCAGACCAAC

Gene: DIP0012: L-lactate permease

Site:
position = -120
score = 4.95395
sequence = TGTGGTCCACCCAAA

Gene: DIP1033: L-lactate permease
 
Corynebacterium efficiens YS-314
 
Corynebacterium glutamicum ATCC 13032
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_0014: L-lactate permease
 
Corynebacterium urealyticum DSM 7109
L-lactate permease
 
CRON 5.
CE2754
 
Corynebacterium amycolatum SK46

Gene: CORAM0001_2075: conserved membrane-spanning protein
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_2404: conserved membrane-spanning protein
 
Corynebacterium diphtheriae NCTC 13129
*
Corynebacterium efficiens YS-314

Site:
position = -75
score = 3.9659
sequence = TCTGGCCGGACCACT

Gene: CE2754: conserved membrane-spanning protein
*
Corynebacterium glutamicum ATCC 13032

Site:
position = -106
score = 5.1022
sequence = TGTGGTCAGACCAAG

Gene: cg3220: conserved membrane-spanning protein
 
Corynebacterium jeikeium K411

Gene: jk0028: conserved membrane-spanning protein
 
Corynebacterium kroppenstedtii DSM 44385
 
Corynebacterium urealyticum DSM 7109
conserved membrane-spanning protein
CE2755
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_0021: phosphoglycolate phosphatase
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE2755: phosphoglycolate phosphatase
 
Corynebacterium glutamicum ATCC 13032

Gene: cg3221: phosphoglycolate phosphatase
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385
 
Corynebacterium urealyticum DSM 7109
phosphoglycolate phosphatase
CE2756
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE2756: NADPH-dependent FMN reductase
 
Corynebacterium glutamicum ATCC 13032

Gene: cg3223: NADPH-dependent FMN reductase
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385
 
Corynebacterium urealyticum DSM 7109
NADPH-dependent FMN reductase
lldR
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE2757: Lactate-responsive regulator LldR in Actinobacteria, GntR family
 
Corynebacterium glutamicum ATCC 13032

Gene: cg3224: Lactate-responsive regulator LldR in Actinobacteria, GntR family
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385
 
Corynebacterium urealyticum DSM 7109
Lactate-responsive regulator LldR in Actinobacteria, GntR family
CE2758
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE2758: hypothetical protein
 
Corynebacterium glutamicum ATCC 13032

Gene: cg3225: hypothetical protein
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385
 
Corynebacterium urealyticum DSM 7109
hypothetical protein
 
CRON 6.
fruR
 
Corynebacterium amycolatum SK46
 
Corynebacterium aurimucosum ATCC 700975
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE1827: Fructose utilization transcriptional regulator FruR, DeoR family
*
Corynebacterium glutamicum ATCC 13032

Site:
position = -110
score = 4.20305
sequence = TACGGTTCTTCCACA

Gene: cg2118: Fructose utilization transcriptional regulator FruR, DeoR family
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385
 
Corynebacterium urealyticum DSM 7109
Fructose utilization transcriptional regulator FruR, DeoR family
pfkB
 
Corynebacterium amycolatum SK46

Gene: CORAM0001_0855: 1-phosphofructokinase
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_1480: 1-phosphofructokinase
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE1828: 1-phosphofructokinase
 
Corynebacterium glutamicum ATCC 13032

Gene: cg2119: 1-phosphofructokinase
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_1091: 1-phosphofructokinase
 
Corynebacterium urealyticum DSM 7109
1-phosphofructokinase
ptsF
 
Corynebacterium amycolatum SK46

Gene: CORAM0001_0854: Fructose-specific PTS, IIABC component
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_1481: Fructose-specific PTS, IIABC component
 
Corynebacterium diphtheriae NCTC 13129
 
Corynebacterium efficiens YS-314

Gene: CE1829: Fructose-specific PTS, IIABC component
 
Corynebacterium glutamicum ATCC 13032

Gene: cg2120: Fructose-specific PTS, IIABC component
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_1092: Fructose-specific PTS, IIABC component
 
Corynebacterium urealyticum DSM 7109
Fructose-specific PTS, IIABC component
ptsH
 
Corynebacterium amycolatum SK46

Gene: CORAM0001_0853: Phosphocarrier protein of PTS system
 
Corynebacterium aurimucosum ATCC 700975

Gene: cauri_1482: Phosphocarrier protein of PTS system
 
Corynebacterium diphtheriae NCTC 13129

Gene: DIP1435: Phosphocarrier protein of PTS system
 
Corynebacterium efficiens YS-314

Gene: CE1830: Phosphocarrier protein of PTS system
 
Corynebacterium glutamicum ATCC 13032

Gene: cg2121: Phosphocarrier protein of PTS system
 
Corynebacterium jeikeium K411
 
Corynebacterium kroppenstedtii DSM 44385

Gene: ckrop_1094: Phosphocarrier protein of PTS system
 
Corynebacterium urealyticum DSM 7109
Phosphocarrier protein of PTS system
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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