Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog FMN - Clostridiaceae

Properties
Regulator type: RNA regulatory element
Name: FMN
RFAM: RF00050
Regulation mode:
Biological process: Riboflavin biosynthesis
Effector: Flavin mononucleotide
Phylum: Firmicutes
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Clostridium beijerincki NCIMB 8052 5 2
Clostridium difficile 630 6 3
Clostridium perfringens ATCC 13124 5 2
Clostridium novyi NT 5 2
Clostridium botulinum A str. ATCC 3502 6 3
Clostridium acetobutylicum ATCC 824 5 2
Clostridium tetani E88 5 2
Clostridium phytofermentans ISDg 1 1
Clostridium cellulolyticum H10 5 2
Clostridium kluyveri DSM 555 5 2
Clostridium sp. OhILAs 1 1
Clostridium bartlettii DSM 16795 6 3
Clostridium bolteae ATCC BAA-613 1 1
Clostridium butyricum 5521 5 2
Clostridium hiranonis DSM 13275 5 2
Clostridium leptum DSM 753 1 1
Clostridium nexile DSM 1787 1 1
Clostridium scindens ATCC 35704 2 2
Clostridium sp. L2-50 3 1
Clostridium sp. SS2/1 7 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
ribD
*
Clostridium beijerincki NCIMB 8052

Site:
position = -447
score = 111.26
sequence = GAAATCTTCGGGGTT...

Gene: Cbei_1224: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium difficile 630

Site:
position = -254
score = 118.75
sequence = ACTTAATCTTCGGGG...

Gene: CD1700: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium perfringens ATCC 13124

Site:
position = -465
score = 122.32
sequence = AAATTCTTCAGGGCA...

Gene: CPF_0546: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium novyi NT

Site:
position = -387
score = 113.43
sequence = TTTAATCCTTCAGGG...

Gene: NT01CX_0715: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -343
score = 106.84
sequence = ATGAATCCTTCAGGG...

Gene: CBO2866: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium acetobutylicum ATCC 824

Site:
position = -170
score = 110.37
sequence = ATGTTCTTCAGGGAT...

Gene: CAC0590: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium tetani E88

Site:
position = -254
score = 108.51
sequence = ACATCCTTCAGGGTT...

Gene: CTC00671: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
 
Clostridium phytofermentans ISDg
*
Clostridium cellulolyticum H10

Site:
position = -206
score = 102.34
sequence = ATGACACTTCAGGGA...

Gene: Ccel_2006: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium kluyveri DSM 555

Site:
position = -394
score = 103.11
sequence = AATATGCTTTCGGGG...

Gene: CKL_2169: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
 
Clostridium sp. OhILAs
*
Clostridium bartlettii DSM 16795

Site:
position = -253
score = 120.74
sequence = GATTATTCTTCGGGG...

Gene: CLOBAR_00909: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02805: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium butyricum 5521

Site:
position = -423
score = 112.25
sequence = TATTAATCTTCAGGG...

Gene: CBY_0685: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium hiranonis DSM 13275

Site:
position = -211
score = 123.02
sequence = ACTATCTTCAGGGCA...

Gene: CLOHIR_00483: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
 
Clostridium leptum DSM 753
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Clostridium sp. L2-50

Gene: CLOL250_02834: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
*
Clostridium sp. SS2/1

Site:
position = -336
score = 117.47
sequence = AACGTCTTCAGGGCA...

Gene: CLOSS21_03172: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193)
ribE
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_1225: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium difficile 630

Gene: CD1699: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium perfringens ATCC 13124

Gene: CPF_0547: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium novyi NT

Gene: NT01CX_0714: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO2865: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium acetobutylicum ATCC 824

Gene: CAC0591: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium tetani E88

Gene: CTC00672: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium phytofermentans ISDg
 
Clostridium cellulolyticum H10

Gene: Ccel_2005: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium kluyveri DSM 555

Gene: CKL_2168: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium sp. OhILAs
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_00908: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02806: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium butyricum 5521

Gene: CBY_0684: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_00484: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium leptum DSM 753
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
*
Clostridium sp. L2-50

Site:
position = -457
score = 105.81
sequence = TTGAAGTCTTCAGGG...

Gene: CLOL250_02833: Riboflavin synthase alpha chain (EC 2.5.1.9)
 
Clostridium sp. SS2/1

Gene: CLOSS21_03173: Riboflavin synthase alpha chain (EC 2.5.1.9)
Riboflavin synthase alpha chain (EC 2.5.1.9)
ribBA
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_1226: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium difficile 630

Gene: CD1698: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium perfringens ATCC 13124

Gene: CPF_0548: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium novyi NT

Gene: NT01CX_0713: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO2864: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium acetobutylicum ATCC 824

Gene: CAC0592: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium tetani E88

Gene: CTC00673: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium phytofermentans ISDg
 
Clostridium cellulolyticum H10

Gene: Ccel_2004: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium kluyveri DSM 555

Gene: CKL_2167: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium sp. OhILAs
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_00907: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02807: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium butyricum 5521

Gene: CBY_0683: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_00485: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
 
Clostridium leptum DSM 753
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Clostridium sp. L2-50

Gene: CLOL250_02832: 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
*2
Clostridium sp. SS2/1

Site:
position = -278
score = 114.87
sequence = AAAATCTTCAGGGCA...

Gene: CLOSS21_01003: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene: CLOSS21_03174: GTP cyclohydrolase II (EC 3.5.4.25)
3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)
ribH
 
Clostridium beijerincki NCIMB 8052

Gene: Cbei_1227: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium difficile 630

Gene: CD1697: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium perfringens ATCC 13124

Gene: CPF_0549: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium novyi NT

Gene: NT01CX_0712: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium botulinum A str. ATCC 3502

Gene: CBO2863: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium acetobutylicum ATCC 824

Gene: CAC0593: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium tetani E88

Gene: CTC00674: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium phytofermentans ISDg
 
Clostridium cellulolyticum H10

Gene: Ccel_2003: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium kluyveri DSM 555

Gene: CKL_2166: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium sp. OhILAs
 
Clostridium bartlettii DSM 16795

Gene: CLOBAR_00906: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium bolteae ATCC BAA-613

Gene: CLOBOL_02808: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium butyricum 5521

Gene: CBY_0682: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium hiranonis DSM 13275

Gene: CLOHIR_00486: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium leptum DSM 753
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Clostridium sp. L2-50

Gene: CLOL250_02831: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
 
Clostridium sp. SS2/1

Gene: CLOSS21_03175: 6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
6,7-dimethyl-8-ribityllumazine synthase (EC 2.5.1.9)
fggY
 
Clostridium beijerincki NCIMB 8052
 
Clostridium difficile 630
 
Clostridium perfringens ATCC 13124
 
Clostridium novyi NT
 
Clostridium botulinum A str. ATCC 3502
 
Clostridium acetobutylicum ATCC 824
 
Clostridium tetani E88
 
Clostridium phytofermentans ISDg
 
Clostridium cellulolyticum H10
 
Clostridium kluyveri DSM 555
 
Clostridium sp. OhILAs
*
Clostridium bartlettii DSM 16795

Site:
position = -211
score = 121.32
sequence = TATATGTCTTCGGGG...

Gene: CLOBAR_00632: Sugar (pentulose and hexulose) kinase, FGGY family
 
Clostridium bolteae ATCC BAA-613
 
Clostridium butyricum 5521
 
Clostridium hiranonis DSM 13275
 
Clostridium leptum DSM 753

Gene: CLOLEP_02876: Sugar (pentulose and hexulose) kinase, FGGY family
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Clostridium sp. L2-50
 
Clostridium sp. SS2/1

Gene: CLOSS21_03176: Sugar (pentulose and hexulose) kinase, FGGY family
Sugar (pentulose and hexulose) kinase, FGGY family
 
CRON 2.
ribZ
 
Clostridium beijerincki NCIMB 8052
*
Clostridium difficile 630

Site:
position = -289
score = 97.53
sequence = TTTTTCTTCATAAAC...

Gene: CD3299: Riboflavin transporter, COG2814 family
 
Clostridium perfringens ATCC 13124
 
Clostridium novyi NT
 
Clostridium botulinum A str. ATCC 3502
 
Clostridium acetobutylicum ATCC 824
 
Clostridium tetani E88
 
Clostridium phytofermentans ISDg
 
Clostridium cellulolyticum H10
 
Clostridium kluyveri DSM 555
 
Clostridium sp. OhILAs
 
Clostridium bartlettii DSM 16795
 
Clostridium bolteae ATCC BAA-613
 
Clostridium butyricum 5521
 
Clostridium hiranonis DSM 13275
 
Clostridium leptum DSM 753
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Clostridium sp. L2-50
 
Clostridium sp. SS2/1
Riboflavin transporter, COG2814 family
 
CRON 3.
ribB
 
Clostridium beijerincki NCIMB 8052
 
Clostridium difficile 630
 
Clostridium perfringens ATCC 13124
 
Clostridium novyi NT
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -366
score = 111.79
sequence = GTATCCTTCAGGGTT...

Gene: CBO2921: 3,4-dihydroxy-2-butanone 4-phosphate synthase
 
Clostridium acetobutylicum ATCC 824
 
Clostridium tetani E88
 
Clostridium phytofermentans ISDg
 
Clostridium cellulolyticum H10
 
Clostridium kluyveri DSM 555
 
Clostridium sp. OhILAs
 
Clostridium bartlettii DSM 16795
 
Clostridium bolteae ATCC BAA-613
 
Clostridium butyricum 5521
 
Clostridium hiranonis DSM 13275
 
Clostridium leptum DSM 753
 
Clostridium nexile DSM 1787
 
Clostridium scindens ATCC 35704
 
Clostridium sp. L2-50
 
Clostridium sp. SS2/1
3,4-dihydroxy-2-butanone 4-phosphate synthase
 
CRON 4.
ribU
*
Clostridium beijerincki NCIMB 8052

Site:
position = -306
score = 121.2
sequence = TATATCTTCAGGGCA...

Gene: Cbei_0464: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium difficile 630

Site:
position = -268
score = 123.2
sequence = AAGATCTTCGGGGCA...

Gene: CD0147: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium perfringens ATCC 13124

Site:
position = -244
score = 117.16
sequence = AAAAAGTCTTCAGGG...

Gene: CPF_2425: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium novyi NT

Site:
position = -229
score = 124.69
sequence = ATAGTATCTTCAGGG...

Gene: NT01CX_0505: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium botulinum A str. ATCC 3502

Site:
position = -211
score = 121.04
sequence = AATATCTTCAGGGCG...

Gene: CBO0178: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium acetobutylicum ATCC 824

Site:
position = -198
score = 121.47
sequence = GAATGATCTTCAGGG...

Gene: CAC2841: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium tetani E88

Site:
position = -211
score = 120.94
sequence = AATATCTTCAGGGCG...

Gene: CTC00331: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium phytofermentans ISDg

Site:
position = -395
score = 94.18
sequence = AAGTTCTTCGGGGCA...

Gene: null: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium cellulolyticum H10

Site:
position = -226
score = 116.22
sequence = AATATCTTCAGGGCA...

Gene: Ccel_3408: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium kluyveri DSM 555

Site:
position = -359
score = 122.75
sequence = ATATAATCTTCAGGG...

Gene: CKL_3611: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium sp. OhILAs

Site:
position = -277
score = 117.93
sequence = TATGATTCTTCAGGG...

Gene: Clos_2474: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium bartlettii DSM 16795

Site:
position = -231
score = 119.42
sequence = AAAAAATCTTCGGGG...

Gene: CLOBAR_00719: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium bolteae ATCC BAA-613

Site:
position = -352
score = 114.43
sequence = TAAAGTTCTTCGGGG...

Gene: CLOBOL_02256: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium butyricum 5521

Site:
position = -276
score = 118.91
sequence = TATATCTTCAGGGCA...

Gene: CBY_3957: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium hiranonis DSM 13275

Site:
position = -311
score = 112.62
sequence = GATGTCTTCAGGGCA...

Gene: CLOHIR_01113: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium leptum DSM 753

Site:
position = -210
score = 119.73
sequence = GCTGTCTTCGGGGCG...

Gene: CLOLEP_01531: Substrate-specific component RibU of riboflavin ECF transporter
*
Clostridium nexile DSM 1787

Site:
position = -239
score = 113.38
sequence = GGATTCTTCGGGGCA...

Gene: CLONEX_02849: Substrate-specific component RibU of riboflavin ECF transporter
*2
Clostridium scindens ATCC 35704

Site:
position = -142
score = 109.59
sequence = AGAGATTCTTCGGGG...

Gene: CLOSCI_02146: Substrate-specific component RibU of riboflavin ECF transporter

Site:
position = -192
score = 91.41
sequence = GAAGTCTTTGTGGCA...

Gene: CLOSCI_02942: Substrate-specific component RibU of riboflavin ECF transporter
 
Clostridium sp. L2-50
*
Clostridium sp. SS2/1

Site:
position = -291
score = 88.7
sequence = TCTCCAACTTCAGGG...

Gene: CLOSS21_01295: Substrate-specific component RibU of riboflavin ECF transporter
Substrate-specific component RibU of riboflavin ECF transporter
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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