Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog LiuR - Various betaproteobacteria

Properties
Regulator type: Transcription factor
Regulator family: MerR
Regulation mode: repressor
Biological process: Branched-chain amino acid degradation
Effector:
Phylum: Proteobacteria/beta
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 31 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Azoarcus sp. EbN1 2 2
Thauera sp. MZ1T 18 6
Dechloromonas aromatica RCB 16 1
Nitrosomonas europaea ATCC 19718
Nitrosospira multiformis ATCC 25196
Thiobacillus denitrificans
Chromobacterium violaceum ATCC 12472 21 6
Neisseria meningitidis MC58
Laribacter hongkongensis HLHK9 17 4
Methylobacillus flagellatus KT
Methylotenera mobilis JLW8
Methylophilales bacterium HTCC2181
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
Tmz1t_2954
 
Azoarcus sp. EbN1
*
Thauera sp. MZ1T

Site:
position = -33
score = 5.92737
sequence = GTTGACGCGAACGTAAAC

Site:
position = -153
score = 5.48106
sequence = GTTGACGCAAACGTCAAT

Site:
position = -159
score = 5.18368
sequence = GTTTACGTTGACGCAAAC

Gene: Tmz1t_2954: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase
badI
 
Azoarcus sp. EbN1

Gene: ebA1954: 2-ketocyclohexanecarboxyl-CoA hydrolase (EC 4.1.3.36)
 
Thauera sp. MZ1T

Gene: Tmz1t_2953: 2-ketocyclohexanecarboxyl-CoA hydrolase (EC 4.1.3.36)
 
Dechloromonas aromatica RCB

Gene: Daro_1616: 2-ketocyclohexanecarboxyl-CoA hydrolase (EC 4.1.3.36)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
2-ketocyclohexanecarboxyl-CoA hydrolase (EC 4.1.3.36)
Tmz1t_2952
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2952: cyclohexa-1,5-dienecarbonyl-CoA hydratase
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
cyclohexa-1,5-dienecarbonyl-CoA hydratase
Tmz1t_2951
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2951: benzoyl-CoA reductase, subunit C
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
benzoyl-CoA reductase, subunit C
Tmz1t_2950
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2950: benzoyl-CoA reductase, subunit B
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
benzoyl-CoA reductase, subunit B
Tmz1t_2949
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2949: benzoyl-CoA reductase, subunit A
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
benzoyl-CoA reductase, subunit A
Tmz1t_2948
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2948: benzoyl-CoA reductase, subunit D
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
benzoyl-CoA reductase, subunit D
Tmz1t_2947
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2947: 4Fe-4S ferredoxin iron-sulfur binding domain protein
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
4Fe-4S ferredoxin iron-sulfur binding domain protein
Tmz1t_2946
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2946: GCN5-related N-acetyltransferase
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
GCN5-related N-acetyltransferase
Tmz1t_2945
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2945: GCN5-related N-acetyltransferase
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
GCN5-related N-acetyltransferase
 
CRON 2.
lcfA
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_3365: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Dechloromonas aromatica RCB

Gene: Daro_0249: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
*
Laribacter hongkongensis HLHK9

Site:
position = -62
score = 5.39433
sequence = GTTTACGTTCACGTAAAT

Gene: LHK_00209: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
livG
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_3364: Branched-chain amino acid ABC transport system, ATP-binding protein LivG
 
Dechloromonas aromatica RCB

Gene: Daro_0250: Branched-chain amino acid ABC transport system, ATP-binding protein LivG
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00210: Branched-chain amino acid ABC transport system, ATP-binding protein LivG
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Branched-chain amino acid ABC transport system, ATP-binding protein LivG
livH
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_3363: Branched-chain amino acid ABC transport system, permease protein LivH
 
Dechloromonas aromatica RCB

Gene: Daro_0251: Branched-chain amino acid ABC transport system, permease protein LivH
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00211: Branched-chain amino acid ABC transport system, permease protein LivH
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Branched-chain amino acid ABC transport system, permease protein LivH
livM
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_3362: Branched-chain amino acid ABC transport system, permease protein LivM
 
Dechloromonas aromatica RCB

Gene: Daro_0252: Branched-chain amino acid ABC transport system, permease protein LivM
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00212: Branched-chain amino acid ABC transport system, permease protein LivM
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Branched-chain amino acid ABC transport system, permease protein LivM
livK
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0253: Branched-chain amino acid ABC transport system, substrate-binding protein LivK
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00213: Branched-chain amino acid ABC transport system, substrate-binding protein LivK
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Branched-chain amino acid ABC transport system, substrate-binding protein LivK
livF
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_3360: Branched-chain amino acid ABC transport system, ATP-binding protein LivF
 
Dechloromonas aromatica RCB

Gene: Daro_0254: Branched-chain amino acid ABC transport system, ATP-binding protein LivF
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00214: Branched-chain amino acid ABC transport system, ATP-binding protein LivF
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Branched-chain amino acid ABC transport system, ATP-binding protein LivF
paaK
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_3359: Putative phenylacetate-CoA ligase
 
Dechloromonas aromatica RCB

Gene: Daro_0255: Putative phenylacetate-CoA ligase
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00215: Putative phenylacetate-CoA ligase
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Putative phenylacetate-CoA ligase
ivdB
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV2085: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00216: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
ivdC
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV2084: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00217: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
ivdE
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV2083: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00218: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17)
ivdD
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV2082: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00219: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
ivdF
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV2081: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_00220: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
ivdG
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
*
Chromobacterium violaceum ATCC 12472

Site:
position = -60
score = 5.46161
sequence = GTTGACGTAAACGTCAAG

Site:
position = -66
score = 6.08613
sequence = GTTGACGTTGACGTAAAC

Gene: CV2086: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)
 
Neisseria meningitidis MC58
*
Laribacter hongkongensis HLHK9

Site:
position = -54
score = 4.82897
sequence = GTTAACGTAAACGTATAT

Site:
position = -60
score = 6.59853
sequence = ATTGACGTTAACGTAAAC

Gene: LHK_00208: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)
 
CRON 3.
CV0303
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
*
Chromobacterium violaceum ATCC 12472

Site:
position = -262
score = 6.22769
sequence = GTTGACGTAAACGTAAAC

Site:
position = -268
score = 5.81331
sequence = TTTGACGTTGACGTAAAC

Gene: CV0303: Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits
CV0302
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV0302: hypothetical protein
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
hypothetical protein
 
CRON 4.
aacS2
 
Azoarcus sp. EbN1

Gene: ebA4661: Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Thauera sp. MZ1T

Gene: Tmz1t_0752: Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
*
Chromobacterium violaceum ATCC 12472

Site:
position = -54
score = 5.77229
sequence = ATTTACGTTTACGTAATC

Site:
position = -48
score = 4.75894
sequence = GTTTACGTAATCGTCAAT

Gene: CV1780: Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
 
CRON 5.
paaH
*
Azoarcus sp. EbN1

Site:
position = -78
score = 5.89612
sequence = GTTGACGTTGACGTCAAC

Gene: ebA5126: Short-chain dehydrogenase/reductase SDR
*
Thauera sp. MZ1T

Site:
position = -84
score = 5.70491
sequence = ATTGACGCCTACGTCAAC

Gene: Tmz1t_1274: Short-chain dehydrogenase/reductase SDR
 
Dechloromonas aromatica RCB

Gene: Daro_0710: Short-chain dehydrogenase/reductase SDR
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Short-chain dehydrogenase/reductase SDR
 
CRON 6.
paaI
 
Azoarcus sp. EbN1
*
Thauera sp. MZ1T

Site:
position = -59
score = 5.5039
sequence = GATTACGTTAACGTTAAC

Gene: Tmz1t_0730: Phenylacetic acid degradation-related protein
*
Dechloromonas aromatica RCB

Site:
position = -45
score = 5.4159
sequence = GTTAACGTAAACGTAAAT

Site:
position = -51
score = 6.54321
sequence = GTTGACGTTAACGTAAAC

Gene: Daro_0101: Phenylacetic acid degradation-related protein
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Phenylacetic acid degradation-related protein
liuA
 
Azoarcus sp. EbN1

Gene: ebA4656: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
 
Thauera sp. MZ1T

Gene: Tmz1t_0748: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
 
Dechloromonas aromatica RCB

Gene: Daro_0100: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
*
Chromobacterium violaceum ATCC 12472

Site:
position = -80
score = 6.45935
sequence = ATTGACGCTTACGTAAAC

Site:
position = -74
score = 5.25036
sequence = GCTTACGTAAACGTAAGC

Gene: CV1766: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
 
Neisseria meningitidis MC58
*
Laribacter hongkongensis HLHK9

Site:
position = -80
score = 6.08613
sequence = GTTGACGTTCACGTAAAC

Gene: LHK_02055: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
cah
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_0731: Carbonic anhydrase (EC 4.2.1.1)
 
Dechloromonas aromatica RCB

Gene: Daro_0099: Carbonic anhydrase (EC 4.2.1.1)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Carbonic anhydrase (EC 4.2.1.1)
ivdA
 
Azoarcus sp. EbN1

Gene: ebA3639: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
 
Thauera sp. MZ1T

Gene: Tmz1t_0732: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
 
Dechloromonas aromatica RCB

Gene: Daro_0098: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV2088: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
 
Neisseria meningitidis MC58
*
Laribacter hongkongensis HLHK9

Site:
position = -33
score = 5.10584
sequence = GTTTCCGTTTACGTAAAA

Gene: LHK_00206: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
Daro_0097
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0097: Permease of the drug/metabolite transporter (DMT) superfamily
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Permease of the drug/metabolite transporter (DMT) superfamily
ivdC
 
Azoarcus sp. EbN1

Gene: ebA3640: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
 
Thauera sp. MZ1T

Gene: Tmz1t_0733: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
 
Dechloromonas aromatica RCB

Gene: Daro_0096: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
Daro_0095
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0095: Protein of unknown function DUF88
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Protein of unknown function DUF88
Daro_0094
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0094: 2-hydroxychromene-2-carboxylate isomerase
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
2-hydroxychromene-2-carboxylate isomerase
Daro_0093
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0093: Lysine decarboxylase family
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Lysine decarboxylase family
liuB
 
Azoarcus sp. EbN1

Gene: ebA4657: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
 
Thauera sp. MZ1T

Gene: Tmz1t_0749: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
 
Dechloromonas aromatica RCB

Gene: Daro_0092: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1764: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_02056: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Daro_0091
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0091: Transcriptional regulator
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Transcriptional regulator
liuC
 
Azoarcus sp. EbN1

Gene: ebA3642: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
 
Thauera sp. MZ1T

Gene: Tmz1t_0750: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
 
Dechloromonas aromatica RCB

Gene: Daro_0090: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1763: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD
 
Azoarcus sp. EbN1

Gene: ebA4659: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
 
Thauera sp. MZ1T

Gene: Tmz1t_0751: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
 
Dechloromonas aromatica RCB

Gene: Daro_0089: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1762: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_02057: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
Daro_0088
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0088: 5-enolpyruvylshikimate-3-phosphate synthase
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
5-enolpyruvylshikimate-3-phosphate synthase
fabG
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T

Gene: Tmz1t_2236: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
 
Dechloromonas aromatica RCB

Gene: Daro_0087: 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)
liuE
 
Azoarcus sp. EbN1

Gene: ebA4662: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
 
Thauera sp. MZ1T

Gene: Tmz1t_0753: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
 
Dechloromonas aromatica RCB

Gene: Daro_0086: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1759: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_02058: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
CV1765
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1765: hypothetical protein
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
hypothetical protein
CV1761
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1761: FOG: TPR repeat protein
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
FOG: TPR repeat protein
CV1760
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1760: probable transcriptional regulator (AraC/XylS family)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
probable transcriptional regulator (AraC/XylS family)
aacS
 
Azoarcus sp. EbN1

Gene: ebA4666: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
 
Thauera sp. MZ1T

Gene: Tmz1t_1658: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
 
Dechloromonas aromatica RCB

Gene: Daro_0177: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472

Gene: CV1758: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_02059: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
liuR
 
Azoarcus sp. EbN1

Gene: ebA3634: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
*
Thauera sp. MZ1T

Site:
position = -135
score = 6.23303
sequence = GTTGACGTTTACGTTAGC

Gene: Tmz1t_2996: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
 
Dechloromonas aromatica RCB

Gene: Daro_0102: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
*2
Chromobacterium violaceum ATCC 12472

Site:
position = -87
score = 5.47325
sequence = GTTTACGTCAACGTCAAC

Site:
position = -93
score = 6.35749
sequence = CTTGACGTTTACGTCAAC

Gene: CV2087: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family

Site:
position = -75
score = 4.95429
sequence = GATTACGTAAACGTAAAT

Site:
position = -81
score = 6.09447
sequence = ATTGACGATTACGTAAAC

Gene: CV1779: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
 
Neisseria meningitidis MC58
*
Laribacter hongkongensis HLHK9

Site:
position = -116
score = 5.59504
sequence = ATATACGTTTACGTTAAC

Site:
position = -110
score = 5.66139
sequence = GTTTACGTTAACGTCAAT

Gene: LHK_00207: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
 
CRON 7.
ebA6516
 
Azoarcus sp. EbN1

Gene: ebA6516: Enoyl-CoA hydratase (EC 4.2.1.17)
*
Thauera sp. MZ1T

Site:
position = -66
score = 5.2622
sequence = GTTGACGTTAACGTTGCC

Gene: Tmz1t_2272: Enoyl-CoA hydratase (EC 4.2.1.17)
 
Dechloromonas aromatica RCB

Gene: Daro_0558: Enoyl-CoA hydratase (EC 4.2.1.17)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Enoyl-CoA hydratase (EC 4.2.1.17)
 
CRON 8.
acsA
*
Azoarcus sp. EbN1

Site:
position = -202
score = 5.27766
sequence = CATGACGTTGACGTCAAC

Gene: ebA1206: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
*
Thauera sp. MZ1T

Site:
position = -84
score = 4.96721
sequence = GTTAACGTCAACGTAAAA

Gene: Tmz1t_1162: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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