Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog NtrC - Various betaproteobacteria

Properties
Regulator type: Transcription factor
Regulator family: Fis
Regulation mode: activator (repressor)
Biological process: Nitrogen assimilation
Effector: Phosphorylated NtrB, signal histidine kinase
Phylum: Proteobacteria/beta
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 47 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Azoarcus sp. EbN1 10 5
Thauera sp. MZ1T 12 6
Dechloromonas aromatica RCB 12 5
Nitrosomonas europaea ATCC 19718
Nitrosospira multiformis ATCC 25196
Thiobacillus denitrificans 8 3
Chromobacterium violaceum ATCC 12472 6 3
Neisseria meningitidis MC58
Laribacter hongkongensis HLHK9 1 1
Methylobacillus flagellatus KT 6 2
Methylotenera mobilis JLW8 13 5
Methylophilales bacterium HTCC2181 7 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
glnA
*
Azoarcus sp. EbN1

Site:
position = -253
score = 5.54432
sequence = TGCACCATGATGGTGCG

Gene: ebA4121: Glutamine synthetase type I (EC 6.3.1.2)
*
Thauera sp. MZ1T

Site:
position = -196
score = 5.14676
sequence = CGCACCATTGAAGTGCA

Site:
position = -228
score = 5.4965
sequence = CGCACCATAGTAGTGCA

Gene: Tmz1t_3648: Glutamine synthetase type I (EC 6.3.1.2)
*
Dechloromonas aromatica RCB

Site:
position = -214
score = 5.66532
sequence = TGCACCAAAATAGTGCG

Site:
position = -183
score = 5.0109
sequence = TGCACGATCGTGGTGCA

Gene: Daro_3763: Glutamine synthetase type I (EC 6.3.1.2)
 
Nitrosomonas europaea ATCC 19718

Gene: NE0504: Glutamine synthetase type I (EC 6.3.1.2)
 
Nitrosospira multiformis ATCC 25196

Gene: Nmul_A2288: Glutamine synthetase type I (EC 6.3.1.2)
*
Thiobacillus denitrificans

Site:
position = -188
score = 4.33197
sequence = CGCCCTATAATGGAGCG

Site:
position = -220
score = 4.97217
sequence = TGCACCAAGACGGGGCA

Gene: Tbd_2503: Glutamine synthetase type I (EC 6.3.1.2)
*
Chromobacterium violaceum ATCC 12472

Site:
position = -202
score = 5.22356
sequence = GGCACCATATCGGTGCA

Site:
position = -172
score = 4.6826
sequence = GGCACCAGAATGGTTCA

Gene: CV3589: Glutamine synthetase type I (EC 6.3.1.2)
 
Neisseria meningitidis MC58

Gene: NMB0359: Glutamine synthetase type I (EC 6.3.1.2)
*
Laribacter hongkongensis HLHK9

Site:
position = -226
score = 5.44086
sequence = TTCACCATTTTGGTGCA

Site:
position = -255
score = 5.11526
sequence = TGCACCATTGATGTGCA

Gene: LHK_01876: Glutamine synthetase type I (EC 6.3.1.2)
*
Methylobacillus flagellatus KT

Site:
position = -189
score = 5.57169
sequence = AGCACCAATATGGTGCA

Site:
position = -158
score = 4.90293
sequence = CGCAATATAGTGGTGCA

Gene: Mfla_2447: Glutamine synthetase type I (EC 6.3.1.2)
*
Methylotenera mobilis JLW8

Site:
position = -153
score = 4.99457
sequence = TGCATTGTATTGGTGCA

Site:
position = -183
score = 5.28408
sequence = TGCACCAAAAATGTGCA

Gene: Mmol_2138: Glutamine synthetase type I (EC 6.3.1.2)
*
Methylophilales bacterium HTCC2181

Site:
position = -173
score = 5.45712
sequence = TGCACTAAATTAGTGCG

Site:
position = -141
score = 4.42018
sequence = AGCATTTAATTGGTGCA

Gene: MB2181_01610: Glutamine synthetase type I (EC 6.3.1.2)
Glutamine synthetase type I (EC 6.3.1.2)
ntrZ
 
Azoarcus sp. EbN1

Gene: ebA4118: Conserved hypothetical signal peptide protein
 
Thauera sp. MZ1T

Gene: Tmz1t_3649: Conserved hypothetical signal peptide protein
 
Dechloromonas aromatica RCB

Gene: Daro_3762: Conserved hypothetical signal peptide protein
 
Nitrosomonas europaea ATCC 19718

Gene: NE0503: Conserved hypothetical signal peptide protein
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_2502: Conserved hypothetical signal peptide protein
 
Chromobacterium violaceum ATCC 12472

Gene: CV3590: Conserved hypothetical signal peptide protein
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT

Gene: Mfla_2448: Conserved hypothetical signal peptide protein
 
Methylotenera mobilis JLW8

Gene: Mmol_2139: Conserved hypothetical signal peptide protein
 
Methylophilales bacterium HTCC2181
Conserved hypothetical signal peptide protein
ntrB
 
Azoarcus sp. EbN1

Gene: ebA4117: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
 
Thauera sp. MZ1T

Gene: Tmz1t_3650: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
*
Dechloromonas aromatica RCB

Site:
position = -204
score = 5.56447
sequence = TGCACCAATACGGTGCG

Gene: Daro_3759: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_2501: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
*
Chromobacterium violaceum ATCC 12472

Site:
position = -118
score = 6.03802
sequence = TGCACCAAAATGGTGCA

Gene: CV3591: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_01905: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
 
Methylobacillus flagellatus KT

Gene: Mfla_2449: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
*
Methylotenera mobilis JLW8

Site:
position = -268
score = 5.68828
sequence = TGCACCTAAATGGTGCA

Site:
position = -9
score = 4.91006
sequence = AGCACTATTATGGTTCA

Gene: Mmol_2140: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
 
Methylophilales bacterium HTCC2181

Gene: MB2181_01605: Nitrogen regulation protein NR(II) (EC 2.7.3.-)
Nitrogen regulation protein NR(II) (EC 2.7.3.-)
ntrC
*
Azoarcus sp. EbN1

Site:
position = -23
score = 5.31558
sequence = CGCACCAAAAAAGTGCA

Gene: ebA4116: Nitrogen regulation protein NR(I), Fis family
*
Thauera sp. MZ1T

Site:
position = -23
score = 5.3698
sequence = CGCACCAGAATAGTGCA

Gene: Tmz1t_3651: Nitrogen regulation protein NR(I), Fis family
 
Dechloromonas aromatica RCB

Gene: Daro_3758: Nitrogen regulation protein NR(I), Fis family
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_2500: Nitrogen regulation protein NR(I), Fis family
 
Chromobacterium violaceum ATCC 12472

Gene: CV3592: Nitrogen regulation protein NR(I), Fis family
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_01906: Nitrogen regulation protein NR(I), Fis family
 
Methylobacillus flagellatus KT

Gene: Mfla_2450: Nitrogen regulation protein NR(I), Fis family
 
Methylotenera mobilis JLW8

Gene: Mmol_2141: Nitrogen regulation protein NR(I), Fis family
 
Methylophilales bacterium HTCC2181

Gene: MB2181_01600: Nitrogen regulation protein NR(I), Fis family
Nitrogen regulation protein NR(I), Fis family
 
CRON 2.
CHP02001
*
Azoarcus sp. EbN1

Site:
position = 20
score = 4.99359
sequence = CGCACCGTTCCGGTGCA

Gene: ebA3154: Conserved hypothetical protein CHP02001
*
Thauera sp. MZ1T

Site:
position = -175
score = 5.43914
sequence = CGCACCACATTGGTGCG

Gene: Tmz1t_0595: Conserved hypothetical protein CHP02001
*
Dechloromonas aromatica RCB

Site:
position = -148
score = 4.96208
sequence = CGCACAGTTTTGGTGCG

Gene: Daro_0052: Conserved hypothetical protein CHP02001
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_0239: Conserved hypothetical protein CHP02001
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT

Gene: Mfla_2512: Conserved hypothetical protein CHP02001
*
Methylotenera mobilis JLW8

Site:
position = -288
score = 4.71349
sequence = CGCCCTTTAATAGTGCA

Gene: Mmol_2289: Conserved hypothetical protein CHP02001
*
Methylophilales bacterium HTCC2181

Site:
position = -282
score = 4.74984
sequence = TGCCCTGAAGTAGTGCA

Gene: MB2181_01245: Conserved hypothetical protein CHP02001
Conserved hypothetical protein CHP02001
glnK
 
Azoarcus sp. EbN1

Gene: ebB95: Nitrogen regulatory protein P-II
 
Thauera sp. MZ1T

Gene: Tmz1t_0594: Nitrogen regulatory protein P-II
 
Dechloromonas aromatica RCB

Gene: Daro_0053: Nitrogen regulatory protein P-II
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_0240: Nitrogen regulatory protein P-II
*
Chromobacterium violaceum ATCC 12472

Site:
position = -176
score = 5.23357
sequence = TGCACCAAAACCGTGCA

Gene: CV4002: Nitrogen regulatory protein P-II
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
*2
Methylobacillus flagellatus KT

Site:
position = -188
score = 5.3427
sequence = TGAACTATTTTGGTGCA

Site:
position = -206
score = 5.08157
sequence = TGCACATCATTGGTGCA

Gene: Mfla_0433: Nitrogen regulatory protein P-II

Gene: Mfla_2513: Nitrogen regulatory protein P-II
 
Methylotenera mobilis JLW8

Gene: Mmol_2290: Nitrogen regulatory protein P-II
 
Methylophilales bacterium HTCC2181

Gene: MB2181_01250: Nitrogen regulatory protein P-II
Nitrogen regulatory protein P-II
amtB
 
Azoarcus sp. EbN1

Gene: ebA3151: Ammonium transporter
 
Thauera sp. MZ1T

Gene: Tmz1t_0593: Ammonium transporter
 
Dechloromonas aromatica RCB

Gene: Daro_0054: Ammonium transporter
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_0241: Ammonium transporter
 
Chromobacterium violaceum ATCC 12472

Gene: CV4003: Ammonium transporter
 
Neisseria meningitidis MC58

Gene: NMB0615: Ammonium transporter
 
Laribacter hongkongensis HLHK9

Gene: LHK_02933: Ammonium transporter
 2
Methylobacillus flagellatus KT

Gene: Mfla_2514: Ammonium transporter

Gene: Mfla_0434: Ammonium transporter
 
Methylotenera mobilis JLW8

Gene: Mmol_2291: Ammonium transporter
 
Methylophilales bacterium HTCC2181

Gene: MB2181_01255: Ammonium transporter
Ammonium transporter
 
CRON 3.
amtB2
*
Azoarcus sp. EbN1

Site:
position = -159
score = 5.19396
sequence = CGCACCGTAATTGTGCA

Gene: ebA4609: Ammonium transporter
*
Thauera sp. MZ1T

Site:
position = -115
score = 4.47361
sequence = CGCACCCCTCTGGTGCG

Site:
position = -49
score = 4.35274
sequence = CGCACTGGAACGGTGCT

Gene: Tmz1t_0457: Ammonium transporter
*
Dechloromonas aromatica RCB

Site:
position = -119
score = 4.89274
sequence = TGCACCAAACAGGTGCT

Site:
position = -53
score = 4.82629
sequence = TGCACTGGAATGGTGCT

Gene: Daro_3703: Ammonium transporter
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
*
Thiobacillus denitrificans

Site:
position = -114
score = 4.33968
sequence = CGCACTTCGGCGGTGCA

Gene: Tbd_1701: Ammonium transporter
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9

Gene: LHK_03154: Ammonium transporter
 
Methylobacillus flagellatus KT
*
Methylotenera mobilis JLW8

Site:
position = -152
score = 5.07588
sequence = TGCACATATTTAGTGCA

Site:
position = -122
score = 5.1301
sequence = TGCACAATGTTAGTGCA

Gene: Mmol_1494: Ammonium transporter
*
Methylophilales bacterium HTCC2181

Site:
position = -134
score = 5.26994
sequence = TGCACCAAAATAATGCA

Gene: MB2181_03520: Ammonium transporter
Ammonium transporter
 
CRON 4.
gltB
*
Azoarcus sp. EbN1

Site:
position = -96
score = 5.16027
sequence = TGCACAGTTTTGGTGCG

Gene: ebA2252: Glutamate synthase, large chain (EC 1.4.1.13)
*
Thauera sp. MZ1T

Site:
position = -141
score = 5.70881
sequence = TGCACCAGATTGGTGCA

Gene: Tmz1t_0842: Glutamate synthase, large chain (EC 1.4.1.13)
 
Dechloromonas aromatica RCB

Gene: Daro_0217: Glutamate synthase, large chain (EC 1.4.1.13)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8

Gene: Mmol_2309: Glutamate synthase, large chain (EC 1.4.1.13)
 
Methylophilales bacterium HTCC2181

Gene: MB2181_01170: Glutamate synthase, large chain (EC 1.4.1.13)
Glutamate synthase, large chain (EC 1.4.1.13)
gltD
 
Azoarcus sp. EbN1

Gene: ebA2251: Glutamate synthase, small chain (EC 1.4.1.13)
 
Thauera sp. MZ1T

Gene: Tmz1t_0843: Glutamate synthase, small chain (EC 1.4.1.13)
 
Dechloromonas aromatica RCB

Gene: Daro_0218: Glutamate synthase, small chain (EC 1.4.1.13)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8

Gene: Mmol_2308: Glutamate synthase, small chain (EC 1.4.1.13)
 
Methylophilales bacterium HTCC2181

Gene: MB2181_01175: Glutamate synthase, small chain (EC 1.4.1.13)
Glutamate synthase, small chain (EC 1.4.1.13)
 
CRON 5.
nasD
 
Azoarcus sp. EbN1

Gene: ebA1216: Nitrite reductase, large subunit (EC 1.7.1.4)
*
Thauera sp. MZ1T

Site:
position = -290
score = 4.33303
sequence = CGCACCAGGGCTGTGCA

Site:
position = -258
score = 4.74326
sequence = TGCACCGCAGCAGTGCG

Gene: Tmz1t_1142: Nitrite reductase, large subunit (EC 1.7.1.4)
*
Dechloromonas aromatica RCB

Site:
position = -199
score = 5.27706
sequence = TGCACGAATTTGGTGCG

Gene: Daro_0816: Nitrite reductase, large subunit (EC 1.7.1.4)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_2309: Nitrite reductase, large subunit (EC 1.7.1.4)
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
*
Methylotenera mobilis JLW8

Site:
position = -219
score = 4.34884
sequence = TGCACCAAAGTAGTAAA

Gene: Mmol_1652: Nitrite reductase, large subunit (EC 1.7.1.4)
 
Methylophilales bacterium HTCC2181
Nitrite reductase, large subunit (EC 1.7.1.4)
narK
 
Azoarcus sp. EbN1

Gene: ebA1213: Nitrate/nitrite transporter
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8

Gene: Mmol_1651: Nitrate/nitrite transporter
 
Methylophilales bacterium HTCC2181
Nitrate/nitrite transporter
pkn
 
Azoarcus sp. EbN1

Gene: ebA1212: Probable serine/threonine-protein kinase SCO3848
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8

Gene: Mmol_1650: Probable serine/threonine-protein kinase SCO3848
 
Methylophilales bacterium HTCC2181
Probable serine/threonine-protein kinase SCO3848
nasE
 
Azoarcus sp. EbN1

Gene: ebA1215: Nitrite reductase, small subunit (EC 1.7.1.4)
 
Thauera sp. MZ1T

Gene: Tmz1t_1143: Nitrite reductase, small subunit (EC 1.7.1.4)
 
Dechloromonas aromatica RCB

Gene: Daro_0817: Nitrite reductase, small subunit (EC 1.7.1.4)
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans

Gene: Tbd_2308: Nitrite reductase, small subunit (EC 1.7.1.4)
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8

Gene: Mmol_1649: Nitrite reductase, small subunit (EC 1.7.1.4)
 
Methylophilales bacterium HTCC2181
Nitrite reductase, small subunit (EC 1.7.1.4)
nasA
 
Azoarcus sp. EbN1

Gene: ebA1211: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
*
Thiobacillus denitrificans

Site:
position = -138
score = 4.4317
sequence = CGCACCAATTTGCGGCG

Gene: Tbd_2310: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8

Gene: Mmol_1648: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)
 
Methylophilales bacterium HTCC2181
Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)
Daro_0818
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0818: Hypothetical protein
 
Nitrosomonas europaea ATCC 19718
 
Nitrosospira multiformis ATCC 25196
 
Thiobacillus denitrificans
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Hypothetical protein
narK
 
Azoarcus sp. EbN1
 
Thauera sp. MZ1T
 
Dechloromonas aromatica RCB

Gene: Daro_0819: Nitrate/nitrite antiporter
 
Nitrosomonas europaea ATCC 19718

Gene: NE0680: Nitrate/nitrite antiporter
 
Nitrosospira multiformis ATCC 25196

Gene: Nmul_A2663: Nitrate/nitrite antiporter
 
Thiobacillus denitrificans

Gene: Tbd_1943: Nitrate/nitrite antiporter
 
Chromobacterium violaceum ATCC 12472
 
Neisseria meningitidis MC58
 
Laribacter hongkongensis HLHK9
 
Methylobacillus flagellatus KT

Gene: Mfla_0331: Nitrate/nitrite antiporter
 
Methylotenera mobilis JLW8
 
Methylophilales bacterium HTCC2181
Nitrate/nitrite antiporter
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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