Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog SiaR - Pasteurellales

Properties
Regulator type: Transcription factor
Regulator family: RpiR
Regulation mode: repressor (activator)
Biological process: Sialic acid utilization
Effector: Glucosamine-6-phosphate
Phylum: Proteobacteria/gamma
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 23 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Haemophilus influenzae Rd KW20 9 2
Aggregatibacter aphrophilus NJ8700 6 2
Pasteurella multocida subsp. multocida str. Pm70 10 3
Mannheimia succiniciproducens MBEL55E
Actinobacillus succinogenes 130Z
Haemophilus somnus 2336 10 3
Actinobacillus pleuropneumoniae serovar 7 str. AP76 8 2
Haemophilus ducreyi 35000HP 6 2
Haemophilus parasuis SH0165 7 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
siaP
*
Haemophilus influenzae Rd KW20

Site:
position = -205
score = 4.76634
sequence = TTTGAAGTGTTTTTTCATA

Gene: HI0146: Sialic acid-binding periplasmic protein SiaP (N-acetylneuraminic-binding protein) (Neu5Ac-binding protein)(Extracytoplasmic solute receptor protein siaP)
*
Aggregatibacter aphrophilus NJ8700

Site:
position = -117
score = 5.29198
sequence = TTTGAAATAAAACTTCATT

Site:
position = -156
score = 4.76067
sequence = TTTGAAGTGATATTTCAAA

Gene: NT05HA_0544: Sialic acid-binding periplasmic protein SiaP (N-acetylneuraminic-binding protein) (Neu5Ac-binding protein)(Extracytoplasmic solute receptor protein siaP)
*
Pasteurella multocida subsp. multocida str. Pm70

Site:
position = -125
score = 5.46746
sequence = TATGAAATAAAACTTCATT

Gene: PM1709: Sialic acid-binding periplasmic protein SiaP (N-acetylneuraminic-binding protein) (Neu5Ac-binding protein)(Extracytoplasmic solute receptor protein siaP)
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
*
Haemophilus somnus 2336

Site:
position = -106
score = 4.41624
sequence = TCTGAAATAAAACTCTATA

Site:
position = -156
score = 4.1005
sequence = TTTGGTGTTTTACTCCAGA

Gene: HSM_1112: Sialic acid-binding periplasmic protein SiaP (N-acetylneuraminic-binding protein) (Neu5Ac-binding protein)(Extracytoplasmic solute receptor protein siaP)
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Sialic acid-binding periplasmic protein SiaP (N-acetylneuraminic-binding protein) (Neu5Ac-binding protein)(Extracytoplasmic solute receptor protein siaP)
siaT
 
Haemophilus influenzae Rd KW20

Gene: HI0147: TRAP-type transport system, large permease component, N-acetylneuraminate transporter / TRAP-type transport system, small permease component, N-acetylneuraminate transporter
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0543: TRAP-type transport system, large permease component, N-acetylneuraminate transporter / TRAP-type transport system, small permease component, N-acetylneuraminate transporter
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1708: TRAP-type transport system, large permease component, N-acetylneuraminate transporter / TRAP-type transport system, small permease component, N-acetylneuraminate transporter
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336

Gene: HSM_1113: TRAP-type transport system, large permease component, N-acetylneuraminate transporter / TRAP-type transport system, small permease component, N-acetylneuraminate transporter
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
TRAP-type transport system, large permease component, N-acetylneuraminate transporter / TRAP-type transport system, small permease component, N-acetylneuraminate transporter
nanM
 
Haemophilus influenzae Rd KW20

Gene: HI0148: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0541: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1707: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
 
CRON 2.
nanE
*
Haemophilus influenzae Rd KW20

Site:
position = -163
score = 4.76634
sequence = TATGAAAAAACACTTCAAA

Gene: HI0145: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
*
Aggregatibacter aphrophilus NJ8700

Site:
position = -117
score = 4.76067
sequence = TTTGAAATATCACTTCAAA

Site:
position = -156
score = 5.29198
sequence = AATGAAGTTTTATTTCAAA

Gene: NT05HA_0545: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
*
Pasteurella multocida subsp. multocida str. Pm70

Site:
position = -43
score = 4.55186
sequence = ATTGGAGTCAATCTTCTTT

Gene: PM1711: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336

Gene: HSM_1110: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_1837: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
*
Haemophilus ducreyi 35000HP

Site:
position = -125
score = 4.27787
sequence = ACAGAAAATTCACTTCTTT

Gene: HD1852: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
*
Haemophilus parasuis SH0165

Site:
position = -43
score = 4.63406
sequence = TTTGGAGTAAATTTTCTTT

Site:
position = -191
score = 4.10276
sequence = AATCGATTAAAACTCGTTT

Gene: HAPS_1216: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanK
 
Haemophilus influenzae Rd KW20

Gene: HI0144: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0546: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1712: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336

Gene: HSM_1109: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_1838: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165

Gene: HAPS_1215: N-acetylmannosamine kinase (EC 2.7.1.60)
N-acetylmannosamine kinase (EC 2.7.1.60)
siaR
 
Haemophilus influenzae Rd KW20

Gene: HI0143: Sialic acid utilization regulator, RpiR family
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0547: Sialic acid utilization regulator, RpiR family
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1714: Sialic acid utilization regulator, RpiR family
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336

Gene: HSM_1107: Sialic acid utilization regulator, RpiR family
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_0748: Sialic acid utilization regulator, RpiR family
 
Haemophilus ducreyi 35000HP

Gene: HD1380: Sialic acid utilization regulator, RpiR family
 
Haemophilus parasuis SH0165

Gene: HAPS_0407: Sialic acid utilization regulator, RpiR family
Sialic acid utilization regulator, RpiR family
nanA
 
Haemophilus influenzae Rd KW20

Gene: HI0142: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0548: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1715: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
 
Haemophilus somnus 2336

Gene: HSM_1106: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_1839: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Haemophilus ducreyi 35000HP

Gene: HD1850: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Haemophilus parasuis SH0165

Gene: HAPS_0406: N-acetylneuraminate lyase (EC 4.1.3.3)
N-acetylneuraminate lyase (EC 4.1.3.3)
nagB
 
Haemophilus influenzae Rd KW20

Gene: HI0141: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0549: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
*
Pasteurella multocida subsp. multocida str. Pm70

Site:
position = -99
score = 4.06676
sequence = ATTGAAAAAAAAATTGATG

Gene: PM0875: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
 
Mannheimia succiniciproducens MBEL55E

Gene: MS2205: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
 
Actinobacillus succinogenes 130Z
*
Haemophilus somnus 2336

Site:
position = -56
score = 5.18547
sequence = TCTGAAATAAAACTTCATT

Gene: HSM_1505: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_1840: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
 
Haemophilus ducreyi 35000HP

Gene: HD1847: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
*
Haemophilus parasuis SH0165

Site:
position = -42
score = 5.29198
sequence = AATGAAGTTTTATTTCAAA

Gene: HAPS_2072: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
Glucosamine-6-phosphate deaminase (EC 3.5.99.6)
nagA
 
Haemophilus influenzae Rd KW20

Gene: HI0140: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_0550: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM0874: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Mannheimia succiniciproducens MBEL55E

Gene: MS2204: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Actinobacillus succinogenes 130Z

Gene: Asuc_1103: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Haemophilus somnus 2336

Gene: HSM_1504: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Gene: APP7_1841: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Haemophilus ducreyi 35000HP

Gene: HD1845: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
 
Haemophilus parasuis SH0165

Gene: HAPS_2071: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
neuA
 
Haemophilus influenzae Rd KW20
 
Aggregatibacter aphrophilus NJ8700
 
Pasteurella multocida subsp. multocida str. Pm70
 
Mannheimia succiniciproducens MBEL55E
 
Actinobacillus succinogenes 130Z
*
Haemophilus somnus 2336

Site:
position = -95
score = 4.1005
sequence = TCTGGAGTAAAACACCAAA

Site:
position = -145
score = 4.41624
sequence = TATAGAGTTTTATTTCAGA

Gene: HSM_1111: Putative N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Site:
position = -40
score = 4.41535
sequence = AATGGTGTATTTATTCATA

Gene: APP7_1836: Putative N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
 
Haemophilus ducreyi 35000HP
 
Haemophilus parasuis SH0165
Putative N-acylneuraminate cytidylyltransferase (EC 2.7.7.43)
yhcH
 
Haemophilus influenzae Rd KW20

Gene: HI0227: Uncharacterized protein yhcH
 
Aggregatibacter aphrophilus NJ8700

Gene: NT05HA_1461: Uncharacterized protein yhcH
 
Pasteurella multocida subsp. multocida str. Pm70

Gene: PM1713: Uncharacterized protein yhcH
 
Mannheimia succiniciproducens MBEL55E

Gene: MS2206: Uncharacterized protein yhcH
 
Actinobacillus succinogenes 130Z

Gene: Asuc_2062: Uncharacterized protein yhcH
 
Haemophilus somnus 2336

Gene: HSM_1108: Uncharacterized protein yhcH
*
Actinobacillus pleuropneumoniae serovar 7 str. AP76

Site:
position = -86
score = 5.318
sequence = ATTGAAGTATATCTTCATT

Gene: APP7_0749: Uncharacterized protein yhcH
*
Haemophilus ducreyi 35000HP

Site:
position = -86
score = 4.4204
sequence = ATTGGAGTAGGTTTTCATT

Gene: HD1379: Uncharacterized protein yhcH
*
Haemophilus parasuis SH0165

Site:
position = -80
score = 4.80955
sequence = TATGGAGTATATTTTCTTT

Site:
position = -153
score = 4.37415
sequence = AATCAAGTAAATTGTGATT

Gene: HAPS_0408: Uncharacterized protein yhcH
Uncharacterized protein yhcH
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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