Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog SiaR - Enterobacteriales

Properties
Regulator type: Transcription factor
Regulator family: RpiR
Regulation mode: repressor (activator)
Biological process: Sialic acid utilization
Effector: Glucosamine-6-phosphate
Phylum: Proteobacteria/gamma
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 14 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Escherichia coli str. K-12 substr. MG1655
Salmonella typhimurium LT2 5 2
Citrobacter koseri ATCC BAA-895
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Enterobacter sp. 638
Erwinia amylovora ATCC 49946
Yersinia pestis KIM 7 3
Serratia proteamaculans 568
Erwinia carotovora subsp. atroseptica SCRI1043
Edwardsiella tarda EIB202 6 3
Proteus mirabilis HI4320 6 2
Photorhabdus luminescens subsp. laumondii TTO1
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
nanM
 
Escherichia coli str. K-12 substr. MG1655
*
Salmonella typhimurium LT2

Site:
position = -32
score = 5.04759
sequence = GATGAAGCTTTACTCCAAT

Gene: STM1130: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
 
Citrobacter koseri ATCC BAA-895
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
 
Yersinia pestis KIM
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
*
Edwardsiella tarda EIB202

Site:
position = -98
score = 4.52564
sequence = AATGGAGCAATACTACAAC

Site:
position = -128
score = 5.22575
sequence = ATTGAAGTGTAACTCCAAA

Gene: ETAE_0932: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
 
Proteus mirabilis HI4320
 
Photorhabdus luminescens subsp. laumondii TTO1
Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
nanC
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2

Gene: STM1131: N-acetylneuraminic acid outer membrane channel protein NanC
 
Citrobacter koseri ATCC BAA-895
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578

Gene: KPN_03267: N-acetylneuraminic acid outer membrane channel protein NanC
 
Enterobacter sp. 638

Gene: Ent638_3298: N-acetylneuraminic acid outer membrane channel protein NanC
 
Erwinia amylovora ATCC 49946
 
Yersinia pestis KIM
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
 
Edwardsiella tarda EIB202

Gene: ETAE_0931: N-acetylneuraminic acid outer membrane channel protein NanC
 
Proteus mirabilis HI4320
 
Photorhabdus luminescens subsp. laumondii TTO1
N-acetylneuraminic acid outer membrane channel protein NanC
 
CRON 2.
nanT
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2
 
Citrobacter koseri ATCC BAA-895
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
*
Yersinia pestis KIM

Site:
position = -188
score = 5.47447
sequence = AATGGAGTTTTACTCCTTT

Gene: y1465: Sialic acid transporter (permease) NanT
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
 
Edwardsiella tarda EIB202
 
Proteus mirabilis HI4320
 
Photorhabdus luminescens subsp. laumondii TTO1
Sialic acid transporter (permease) NanT
 
CRON 3.
nanE
 
Escherichia coli str. K-12 substr. MG1655
*
Salmonella typhimurium LT2

Site:
position = -37
score = 4.90074
sequence = AACGGAGCAAAACTTCAAA

Gene: STM1129: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
 
Citrobacter koseri ATCC BAA-895

Gene: CKO_04626: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578

Gene: KPN_03626: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
*
Yersinia pestis KIM

Site:
position = -46
score = 5.91664
sequence = AATGGAGTTAAACTTCATT

Gene: y1459: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
*
Edwardsiella tarda EIB202

Site:
position = -40
score = 4.32862
sequence = TATGGAGTTCAATTCTAAA

Site:
position = -70
score = 5.05494
sequence = GATGGAGTATTGCTCCATA

Gene: ETAE_0521: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
*
Proteus mirabilis HI4320

Site:
position = -41
score = 4.47207
sequence = TTCGGAGTTACATTTCAAA

Site:
position = -71
score = 4.48166
sequence = TGAGAAATAAAACTCCGTA

Gene: PMI2978: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
 
Photorhabdus luminescens subsp. laumondii TTO1
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanK
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2
 
Citrobacter koseri ATCC BAA-895

Gene: CKO_04625: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
*
Yersinia pestis KIM

Site:
position = -111
score = 5.43783
sequence = AAAGGAGTTTAACTCCAAA

Gene: y1461: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
 
Edwardsiella tarda EIB202

Gene: ETAE_0520: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Proteus mirabilis HI4320

Gene: PMI2977: N-acetylmannosamine kinase (EC 2.7.1.60)
 
Photorhabdus luminescens subsp. laumondii TTO1
N-acetylmannosamine kinase (EC 2.7.1.60)
nanP
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2

Gene: STM1128: Predicted sialic acid transporter
 
Citrobacter koseri ATCC BAA-895
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
 
Yersinia pestis KIM
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
 
Edwardsiella tarda EIB202

Gene: ETAE_0930: Predicted sialic acid transporter
 
Proteus mirabilis HI4320

Gene: PMI2976: Predicted sialic acid transporter
 
Photorhabdus luminescens subsp. laumondii TTO1
Predicted sialic acid transporter
yhcH
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2
 
Citrobacter koseri ATCC BAA-895

Gene: CKO_04624: Uncharacterized protein yhcH
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
 
Yersinia pestis KIM

Gene: y1462: Uncharacterized protein yhcH
 
Serratia proteamaculans 568

Gene: Spro_1482: Uncharacterized protein yhcH
 
Erwinia carotovora subsp. atroseptica SCRI1043
 
Edwardsiella tarda EIB202

Gene: ETAE_0519: Uncharacterized protein yhcH
 
Proteus mirabilis HI4320

Gene: PMI2975: Uncharacterized protein yhcH
 
Photorhabdus luminescens subsp. laumondii TTO1
Uncharacterized protein yhcH
siaR
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2

Gene: STM1127: Sialic acid utilization regulator, RpiR family
 
Citrobacter koseri ATCC BAA-895
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
 
Yersinia pestis KIM

Gene: y1464: Sialic acid utilization regulator, RpiR family
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
 
Edwardsiella tarda EIB202

Gene: ETAE_0929: Sialic acid utilization regulator, RpiR family
 
Proteus mirabilis HI4320

Gene: PMI2974: Sialic acid utilization regulator, RpiR family
 
Photorhabdus luminescens subsp. laumondii TTO1
Sialic acid utilization regulator, RpiR family
y1463
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2
 
Citrobacter koseri ATCC BAA-895
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
 
Yersinia pestis KIM

Gene: y1463: hypothetical protein
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
 
Edwardsiella tarda EIB202
 
Proteus mirabilis HI4320
 
Photorhabdus luminescens subsp. laumondii TTO1
hypothetical protein
nanA
 
Escherichia coli str. K-12 substr. MG1655
 
Salmonella typhimurium LT2
 
Citrobacter koseri ATCC BAA-895
 
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
 
Enterobacter sp. 638
 
Erwinia amylovora ATCC 49946
 
Yersinia pestis KIM

Gene: y1458: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Serratia proteamaculans 568
 
Erwinia carotovora subsp. atroseptica SCRI1043
*
Edwardsiella tarda EIB202

Site:
position = -61
score = 4.98094
sequence = AATGGAGCCAAACTCCATA

Gene: ETAE_0928: N-acetylneuraminate lyase (EC 4.1.3.3)
*
Proteus mirabilis HI4320

Site:
position = -29
score = 4.84438
sequence = AAAGAAATTAATCTCCATA

Site:
position = -59
score = 5.37928
sequence = TATAGAGTTAAACTCCATA

Gene: PMI2973: N-acetylneuraminate lyase (EC 4.1.3.3)
 
Photorhabdus luminescens subsp. laumondii TTO1
N-acetylneuraminate lyase (EC 4.1.3.3)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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