Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog HypR - Pseudomonadaceae

Properties
Regulator type: Transcription factor
Regulator family: GntR/Others
Regulation mode: activator (repressor)
Biological process: Proline and 4-hydrohyproline utilization
Effector: Proline; 4-hydroxyproline
Phylum: Proteobacteria/gamma
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 3 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Pseudomonas aeruginosa PAO1 11 3
Pseudomonas entomophila L48
Pseudomonas putida KT2440
Pseudomonas syringae pv. tomato str. DC3000
Pseudomonas fluorescens Pf-5
Pseudomonas mendocina ymp
Pseudomonas stutzeri A1501
Azotobacter vinelandii AvOP
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
hypM
*
Pseudomonas aeruginosa PAO1

Site:
position = -67
score = 3.80123
sequence = ATCGTATACGAA

Gene: PA1260: Predicted hydroxyproline ABC transporter, substrate-binding protein
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Predicted hydroxyproline ABC transporter, substrate-binding protein
hypX
 
Pseudomonas aeruginosa PAO1

Gene: PA1259: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
hypN
 
Pseudomonas aeruginosa PAO1

Gene: PA1258: Predicted hydroxyproline ABC transporter, permease protein
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Predicted hydroxyproline ABC transporter, permease protein
hypP
 
Pseudomonas aeruginosa PAO1

Gene: PA1257: Predicted hydroxyproline ABC transporter, permease protein
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Predicted hydroxyproline ABC transporter, permease protein
hypQ
 
Pseudomonas aeruginosa PAO1

Gene: PA1256: Predicted hydroxyproline ABC transporter, ATP-binding protein
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Predicted hydroxyproline ABC transporter, ATP-binding protein
hypY
 
Pseudomonas aeruginosa PAO1

Gene: PA1255: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
 
CRON 2.
hypR
*
Pseudomonas aeruginosa PAO1

Site:
position = -61
score = 4.49449
sequence = TTCGTATACAAT

Gene: PA1269: Predicted regulator for proline and hydrohyproline utilization, GntR family
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Predicted regulator for proline and hydrohyproline utilization, GntR family
hypE
 
Pseudomonas aeruginosa PAO1

Gene: PA1268: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
 
Pseudomonas entomophila L48

Gene: PSEEN4050: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
 
Pseudomonas putida KT2440

Gene: PP1258: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5

Gene: PFL_1412: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
hypO
 
Pseudomonas aeruginosa PAO1

Gene: PA1267: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
 
CRON 3.
hypD
*
Pseudomonas aeruginosa PAO1

Site:
position = -32
score = 3.66748
sequence = TTCGTATACGAA

Gene: PA1254: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5

Gene: PFL_1413: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
 
Pseudomonas mendocina ymp
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
hypH
 
Pseudomonas aeruginosa PAO1

Gene: PA1253: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
 
Pseudomonas entomophila L48
 
Pseudomonas putida KT2440

Gene: PP2585: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
 
Pseudomonas syringae pv. tomato str. DC3000
 
Pseudomonas fluorescens Pf-5

Gene: PFL_1415: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
 
Pseudomonas mendocina ymp

Gene: Pmen_0227: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
 
Pseudomonas stutzeri A1501
 
Azotobacter vinelandii AvOP
Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD