Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog CtsR - Bacillales

Properties
Regulator type: Transcription factor
Regulator family: CtsR
Regulation mode: repressor
Biological process: Heat shock response
Effector: Heat shock
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 41 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Bacillus subtilis subsp. subtilis str. 168 8 3
Bacillus amyloliquefaciens FZB42 9 4
Bacillus pumilus SAFR-032 9 4
Bacillus licheniformis DSM 13 10 5
Anoxybacillus flavithermus WK1 8 4
Geobacillus kaustophilus HTA426 8 4
Bacillus cereus ATCC 14579 10 5
Bacillus halodurans C-125 9 4
Bacillus clausii KSM-K16 8 3
Oceanobacillus iheyensis HTE831 7 3
Paenibacillus sp. JDR-2 7 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
clpE
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -84
score = 8.42687
sequence = AGTCAAA-(3)-GGTCAAA

Gene: BSU13700: ATP-dependent Clp protease (class III stress gene)
*
Bacillus amyloliquefaciens FZB42

Site:
position = -85
score = 7.73477
sequence = AATCAAA-(3)-GGTCAAA

Gene: RBAM_013460: ATP-dependent Clp protease (class III stress gene)
*
Bacillus pumilus SAFR-032

Site:
position = -89
score = 8.42687
sequence = AGTCAAA-(3)-GGTCAAA

Gene: BPUM_1261: ATP-dependent Clp protease (class III stress gene)
*
Bacillus licheniformis DSM 13

Site:
position = -84
score = 7.52948
sequence = AGTCAGA-(3)-GGTCAAA

Gene: BLi01525: ATP-dependent Clp protease (class III stress gene)
*
Anoxybacillus flavithermus WK1

Site:
position = 5
score = 8.42687
sequence = AGTCAAA-(3)-GGTCAAA

Gene: Aflv_1984: ATP-dependent Clp protease (class III stress gene)
*
Geobacillus kaustophilus HTA426

Site:
position = -87
score = 8.42687
sequence = AGTCAAA-(3)-GGTCAAA

Gene: GK0968: ATP-dependent Clp protease (class III stress gene)
 
Bacillus cereus ATCC 14579
*
Bacillus halodurans C-125

Site:
position = -86
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: BH2179: ATP-dependent Clp protease (class III stress gene)
*
Bacillus clausii KSM-K16

Site:
position = -60
score = 8.42687
sequence = GGTCAAA-(3)-AGTCAAA

Gene: ABC3449: ATP-dependent Clp protease (class III stress gene)
*
Oceanobacillus iheyensis HTE831

Site:
position = -106
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: OB0881: ATP-dependent Clp protease (class III stress gene)
 
Paenibacillus sp. JDR-2
ATP-dependent Clp protease (class III stress gene)
 
CRON 2.
clpB
 
Bacillus subtilis subsp. subtilis str. 168
 
Bacillus amyloliquefaciens FZB42
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
*
Anoxybacillus flavithermus WK1

Site:
position = -34
score = 8.42687
sequence = GGTCAAA-(3)-AGTCAAA

Gene: Aflv_2144: Class III stress response-related ATPase
*
Geobacillus kaustophilus HTA426

Site:
position = -30
score = 8.42687
sequence = AGTCAAA-(3)-GGTCAAA

Gene: GK0799: Class III stress response-related ATPase
*
Bacillus cereus ATCC 14579

Site:
position = -36
score = 8.42687
sequence = GGTCAAA-(3)-AGTCAAA

Gene: BC1168: Class III stress response-related ATPase
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Class III stress response-related ATPase
 
CRON 3.
gs14
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU35990: General stress protein 14
*
Bacillus amyloliquefaciens FZB42

Site:
position = -27
score = 7.52948
sequence = GGTAAAA-(3)-AGTCAAA

Gene: RBAM_033150: General stress protein 14
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13

Gene: BLi03696: General stress protein 14
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
General stress protein 14
 
CRON 4.
BLi03709
 
Bacillus subtilis subsp. subtilis str. 168
 
Bacillus amyloliquefaciens FZB42
*
Bacillus pumilus SAFR-032

Site:
position = -175
score = 7.97067
sequence = GGTCAAT-(3)-GGTCAAA

Gene: BPUM_3100: TM2 domain containing protein
*
Bacillus licheniformis DSM 13

Site:
position = -187
score = 7.97067
sequence = GGTCAAT-(3)-GGTCAAA

Gene: BLi03709: TM2 domain containing protein
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2

Gene: Pjdr2_1115: TM2 domain containing protein
TM2 domain containing protein
 
CRON 5.
ctsR
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -38
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: BSU00830: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Bacillus amyloliquefaciens FZB42

Site:
position = -38
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: RBAM_001080: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Bacillus pumilus SAFR-032

Site:
position = -38
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: BPUM_0068: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Bacillus licheniformis DSM 13

Site:
position = -39
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: BLi00101: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Anoxybacillus flavithermus WK1

Site:
position = -41
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: Aflv_0074: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Geobacillus kaustophilus HTA426

Site:
position = -100
score = 8.42687
sequence = GGTCAAA-(3)-AGTCAAA

Gene: GK0075: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Bacillus cereus ATCC 14579

Site:
position = -38
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: BC0099: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Bacillus halodurans C-125

Site:
position = -86
score = 8.42687
sequence = GGTCAAA-(3)-AGTCAAA

Gene: BH0100: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Bacillus clausii KSM-K16

Site:
position = -90
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: ABC0118: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Oceanobacillus iheyensis HTE831

Site:
position = -61
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: OB0090: Transcriptional repressor of class III stress genes, CtdR fsmily
*
Paenibacillus sp. JDR-2

Site:
position = -80
score = 8.45821
sequence = AGTCAAA-(3)-AGTCAAA

Gene: Pjdr2_5718: Transcriptional repressor of class III stress genes, CtdR fsmily
Transcriptional repressor of class III stress genes, CtdR fsmily
mcsA
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU00840: Modulator of heat shock repressor CtsR, McsA
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_001090: Modulator of heat shock repressor CtsR, McsA
 
Bacillus pumilus SAFR-032

Gene: BPUM_0069: Modulator of heat shock repressor CtsR, McsA
 
Bacillus licheniformis DSM 13

Gene: BLi00102: Modulator of heat shock repressor CtsR, McsA
 
Anoxybacillus flavithermus WK1

Gene: Aflv_0075: Modulator of heat shock repressor CtsR, McsA
 
Geobacillus kaustophilus HTA426

Gene: GK0076: Modulator of heat shock repressor CtsR, McsA
 
Bacillus cereus ATCC 14579

Gene: BC0100: Modulator of heat shock repressor CtsR, McsA
 
Bacillus halodurans C-125

Gene: BH0101: Modulator of heat shock repressor CtsR, McsA
 
Bacillus clausii KSM-K16

Gene: ABC0119: Modulator of heat shock repressor CtsR, McsA
 
Oceanobacillus iheyensis HTE831

Gene: OB0091: Modulator of heat shock repressor CtsR, McsA
 
Paenibacillus sp. JDR-2

Gene: Pjdr2_5717: Modulator of heat shock repressor CtsR, McsA
Modulator of heat shock repressor CtsR, McsA
mcsB
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU00850: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_001100: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Bacillus pumilus SAFR-032

Gene: BPUM_0070: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Bacillus licheniformis DSM 13

Gene: BLi00103: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Anoxybacillus flavithermus WK1

Gene: Aflv_0076: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Geobacillus kaustophilus HTA426

Gene: GK0077: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Bacillus cereus ATCC 14579

Gene: BC0101: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Bacillus halodurans C-125

Gene: BH0102: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Bacillus clausii KSM-K16

Gene: ABC0120: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Oceanobacillus iheyensis HTE831

Gene: OB0092: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
 
Paenibacillus sp. JDR-2

Gene: Pjdr2_5716: Tyrosine kinase McSB, modulator of heat shock repressor CtsR
Tyrosine kinase McSB, modulator of heat shock repressor CtsR
clpC
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU00860: class III stress response-related ATPase, AAA+ superfamily
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_001110: class III stress response-related ATPase, AAA+ superfamily
 
Bacillus pumilus SAFR-032

Gene: BPUM_0071: class III stress response-related ATPase, AAA+ superfamily
 
Bacillus licheniformis DSM 13

Gene: BLi00104: class III stress response-related ATPase, AAA+ superfamily
 
Anoxybacillus flavithermus WK1

Gene: Aflv_0077: class III stress response-related ATPase, AAA+ superfamily
 
Geobacillus kaustophilus HTA426

Gene: GK0078: class III stress response-related ATPase, AAA+ superfamily
 
Bacillus cereus ATCC 14579

Gene: BC0102: class III stress response-related ATPase, AAA+ superfamily
 
Bacillus halodurans C-125

Gene: BH0103: class III stress response-related ATPase, AAA+ superfamily
 
Bacillus clausii KSM-K16

Gene: ABC0121: class III stress response-related ATPase, AAA+ superfamily
 
Oceanobacillus iheyensis HTE831

Gene: OB0093: class III stress response-related ATPase, AAA+ superfamily
 
Paenibacillus sp. JDR-2

Gene: Pjdr2_5715: class III stress response-related ATPase, AAA+ superfamily
class III stress response-related ATPase, AAA+ superfamily
radA
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU00870: DNA repair protein RadA
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_001120: DNA repair protein RadA
 
Bacillus pumilus SAFR-032

Gene: BPUM_0072: DNA repair protein RadA
 
Bacillus licheniformis DSM 13

Gene: BLi00105: DNA repair protein RadA
 
Anoxybacillus flavithermus WK1

Gene: Aflv_0078: DNA repair protein RadA
 
Geobacillus kaustophilus HTA426

Gene: GK0079: DNA repair protein RadA
 
Bacillus cereus ATCC 14579

Gene: BC0103: DNA repair protein RadA
 
Bacillus halodurans C-125

Gene: BH0104: DNA repair protein RadA
 
Bacillus clausii KSM-K16

Gene: ABC0122: DNA repair protein RadA
 
Oceanobacillus iheyensis HTE831

Gene: OB0094: DNA repair protein RadA
 
Paenibacillus sp. JDR-2

Gene: Pjdr2_5713: DNA repair protein RadA
DNA repair protein RadA
yacK
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU00880: DNA integrity scanning protein DisA
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_001130: DNA integrity scanning protein DisA
 
Bacillus pumilus SAFR-032

Gene: BPUM_0073: DNA integrity scanning protein DisA
 
Bacillus licheniformis DSM 13

Gene: BLi00106: DNA integrity scanning protein DisA
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579

Gene: BC0104: DNA integrity scanning protein DisA
 
Bacillus halodurans C-125

Gene: BH0105: DNA integrity scanning protein DisA
 
Bacillus clausii KSM-K16

Gene: ABC0123: DNA integrity scanning protein DisA
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2

Gene: Pjdr2_5712: DNA integrity scanning protein DisA
DNA integrity scanning protein DisA
 
CRON 6.
BC2214
 
Bacillus subtilis subsp. subtilis str. 168
 
Bacillus amyloliquefaciens FZB42
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
*
Bacillus cereus ATCC 14579

Site:
position = -104
score = 6.98729
sequence = CATCAAA-(3)-GGTCAAA

Gene: BC2214: Small heat shock protein
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Small heat shock protein
 
CRON 7.
clpP
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -69
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: BSU34540: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Bacillus amyloliquefaciens FZB42

Site:
position = -69
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: RBAM_031850: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Bacillus pumilus SAFR-032

Site:
position = -69
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: BPUM_3102: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Bacillus licheniformis DSM 13

Site:
position = -70
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: BLi03710: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Anoxybacillus flavithermus WK1

Site:
position = -70
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: Aflv_2522: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Geobacillus kaustophilus HTA426

Site:
position = -77
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: GK3062: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Bacillus cereus ATCC 14579

Site:
position = -65
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: BC5152: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Bacillus halodurans C-125

Site:
position = -93
score = -0.130742
sequence = TTTGACC-(3)-TTTGACC

Gene: BH3564: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Bacillus clausii KSM-K16

Site:
position = -87
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: ABC3026: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Oceanobacillus iheyensis HTE831

Site:
position = -89
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: OB2456: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
*
Paenibacillus sp. JDR-2

Site:
position = -85
score = 0.745489
sequence = TTTGACT-(3)-TTTGACT

Gene: Pjdr2_0175: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92)
 
CRON 8.
BC4452
 
Bacillus subtilis subsp. subtilis str. 168
 
Bacillus amyloliquefaciens FZB42
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
*
Bacillus cereus ATCC 14579

Site:
position = -179
score = 0.616734
sequence = TTTGACC-(3)-ATTGACC

Gene: BC4452: Hypothetical protein
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Hypothetical protein
 
CRON 9.
sspI
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU28660: Small acid-soluble spore protein SspI
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_025730: Small acid-soluble spore protein SspI
 
Bacillus pumilus SAFR-032

Gene: BPUM_2524: Small acid-soluble spore protein SspI
*
Bacillus licheniformis DSM 13

Site:
position = -112
score = -0.151907
sequence = TTTGACT-(3)-TTTGTCT

Gene: BLi03018: Small acid-soluble spore protein SspI
 
Anoxybacillus flavithermus WK1

Gene: Aflv_0539: Small acid-soluble spore protein SspI
 
Geobacillus kaustophilus HTA426

Gene: GK2712: Small acid-soluble spore protein SspI
 
Bacillus cereus ATCC 14579

Gene: BC4563: Small acid-soluble spore protein SspI
*
Bacillus halodurans C-125

Site:
position = -165
score = 0.272958
sequence = TTTTCCA-(3)-TTTGACT

Gene: BH3113: Small acid-soluble spore protein SspI
 
Bacillus clausii KSM-K16

Gene: ABC2682: Small acid-soluble spore protein SspI
 
Oceanobacillus iheyensis HTE831

Gene: OB2133: Small acid-soluble spore protein SspI
 
Paenibacillus sp. JDR-2

Gene: Pjdr2_1121: Small acid-soluble spore protein SspI
Small acid-soluble spore protein SspI
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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