Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Regulog ComA - Bacillales

Properties
Regulator type: Transcription factor
Regulator family: LuxR
Regulation mode: activator
Biological process: Competence
Effector: ComP, sensor histidine kinase (ComX)
Phylum: Firmicutes
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 16 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Bacillus subtilis subsp. subtilis str. 168 13 7
Bacillus amyloliquefaciens FZB42 8 4
Bacillus pumilus SAFR-032 7 2
Bacillus licheniformis DSM 13 5 2
Anoxybacillus flavithermus WK1
Geobacillus kaustophilus HTA426
Bacillus cereus ATCC 14579
Bacillus halodurans C-125
Bacillus clausii KSM-K16
Oceanobacillus iheyensis HTE831
Paenibacillus sp. JDR-2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
degQ
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -145
score = 8.09313
sequence = TTGCGGTGTCACGCAG-(16)-TTTCGG

Gene: BSU31720: Degradation enzyme regulation protein DegQ
*
Bacillus amyloliquefaciens FZB42

Site:
position = -146
score = 8.09313
sequence = TTGCGGTGTCACGCAG-(17)-TTTCGG

Gene: RBAM_028800: Degradation enzyme regulation protein DegQ
*
Bacillus pumilus SAFR-032

Site:
position = -145
score = 8.41765
sequence = TTGCGGTATCACGCAC-(16)-TTTCGG

Gene: BPUM_2841: Degradation enzyme regulation protein DegQ
*
Bacillus licheniformis DSM 13

Site:
position = -143
score = 8.40522
sequence = TTGCGGTGTAACGCAT-(16)-TTTCGG

Gene: BLi03360: Degradation enzyme regulation protein DegQ
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Degradation enzyme regulation protein DegQ
 
CRON 2.
rapC
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -104
score = 7.2488
sequence = TTGCGTGCTCCCGAAA-(16)-TTTCGG

Gene: BSU03770: Response regulator aspartate phosphatase
*
Bacillus amyloliquefaciens FZB42

Site:
position = -103
score = 7.1194
sequence = TTGCGCTCTGCCGAAA-(15)-TTTCGG

Gene: RBAM_004010: Response regulator aspartate phosphatase
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Response regulator aspartate phosphatase
phrC
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU03780: Secreted regulator of the activity of phosphatase RapC and competence and sporulation stimulating factor (CSF)
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_004020: Secreted regulator of the activity of phosphatase RapC and competence and sporulation stimulating factor (CSF)
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Secreted regulator of the activity of phosphatase RapC and competence and sporulation stimulating factor (CSF)
 
CRON 3.
rapA
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -106
score = 8.06221
sequence = TTGCGGTTAGCCGAAA-(8)-TTGCGG

Gene: BSU12430: Response regulator aspartate phosphatase
*
Bacillus amyloliquefaciens FZB42

Site:
position = -112
score = 7.29514
sequence = TTGCGGATATCCGAAA-(8)-TTGCGG

Gene: RBAM_012450: Response regulator aspartate phosphatase
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Response regulator aspartate phosphatase
phrA
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU12440: Secreted inhibitor of the activity of phosphatase RapA
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_012460: Secreted inhibitor of the activity of phosphatase RapA
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Secreted inhibitor of the activity of phosphatase RapA
 
CRON 4.
rapF
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -106
score = 8.37795
sequence = ATGCGGTGTAACGAAA-(7)-TTGCGG

Gene: BSU37460: Response regulator aspartate phosphatase
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_034530: Response regulator aspartate phosphatase
 
Bacillus pumilus SAFR-032

Gene: BPUM_2152: Response regulator aspartate phosphatase
 
Bacillus licheniformis DSM 13

Gene: BLi01063: Response regulator aspartate phosphatase
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Response regulator aspartate phosphatase
phrF
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU37470: Secreted regulator of the activity of phosphatase RapF
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_034540: Secreted regulator of the activity of phosphatase RapF
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Secreted regulator of the activity of phosphatase RapF
 
CRON 5.
pel
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -124
score = 7.95263
sequence = TTGCAGAATGCCGCAA-(16)-TTTCGG

Gene: BSU07560: Pectate lyase precursor (EC 4.2.2.2)
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_007720: Pectate lyase precursor (EC 4.2.2.2)
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13

Gene: BLi01404: Pectate lyase precursor (EC 4.2.2.2)
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Pectate lyase precursor (EC 4.2.2.2)
 
CRON 6.
rapE
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -108
score = 7.90335
sequence = TTGCGGTCTCACCGAA-(8)-TTGCGG

Gene: BSU25830: Response regulator aspartate phosphatase
 
Bacillus amyloliquefaciens FZB42
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13

Gene: BLi02480: Response regulator aspartate phosphatase
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Response regulator aspartate phosphatase
phrE
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU25840: Regulator of the activity of phosphatase RapE
 
Bacillus amyloliquefaciens FZB42
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Regulator of the activity of phosphatase RapE
 
CRON 7.
srfAC
*
Bacillus subtilis subsp. subtilis str. 168

Site:
position = -364
score = 9.51002
sequence = TTTCGGCATCCCGCAT-(17)-TTTCGG

Gene: BSU03480: Surfactin synthetase subunit 1
*
Bacillus amyloliquefaciens FZB42

Site:
position = -337
score = 8.98174
sequence = TTTCGGTGTGCCGCAT-(17)-TTTCGG

Gene: RBAM_003650: Surfactin synthetase subunit 1
*
Bacillus pumilus SAFR-032

Site:
position = -330
score = 8.8041
sequence = ATTCGGCATAACGCAT-(17)-TTTCGG

Gene: BPUM_0319: Surfactin synthetase subunit 1
*
Bacillus licheniformis DSM 13

Site:
position = -372
score = 9.26255
sequence = ATTCGGTATCCCGCAT-(17)-TTTCGG

Site:
position = -405
score = 8.20459
sequence = TTTCGGGATCGCGCAT-(17)-ATTCGG

Gene: BLi00401: Surfactin synthetase subunit 1
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Surfactin synthetase subunit 1
srfAB
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU03490: Surfactin synthetase subunit 2
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_003660: Surfactin synthetase subunit 2
 
Bacillus pumilus SAFR-032

Gene: BPUM_0320: Surfactin synthetase subunit 2
 
Bacillus licheniformis DSM 13

Gene: BLi00402: Surfactin synthetase subunit 2
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Surfactin synthetase subunit 2
srfAC
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU03510: Surfactin synthetase subunit 3
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_003680: Surfactin synthetase subunit 3
 
Bacillus pumilus SAFR-032

Gene: BPUM_0321: Surfactin synthetase subunit 3
 
Bacillus licheniformis DSM 13

Gene: BLi00403: Surfactin synthetase subunit 3
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Surfactin synthetase subunit 3
BPUM_0322
 
Bacillus subtilis subsp. subtilis str. 168
 
Bacillus amyloliquefaciens FZB42
 
Bacillus pumilus SAFR-032

Gene: BPUM_0322: Nonribosomal peptide synthetase subunit
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Nonribosomal peptide synthetase subunit
BPUM_0323
 
Bacillus subtilis subsp. subtilis str. 168
 
Bacillus amyloliquefaciens FZB42
 
Bacillus pumilus SAFR-032

Gene: BPUM_0323: Nonribosomal peptide synthetase subunit
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Nonribosomal peptide synthetase subunit
srfAD
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU03520: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_003690: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)
 
Bacillus pumilus SAFR-032

Gene: BPUM_0324: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)
 
Bacillus licheniformis DSM 13

Gene: BLi00404: Surfactin synthetase thioesterase subunit (EC 3.1.2.-)
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Surfactin synthetase thioesterase subunit (EC 3.1.2.-)
comS
 
Bacillus subtilis subsp. subtilis str. 168

Gene: BSU03500: Competence protein S
 
Bacillus amyloliquefaciens FZB42

Gene: RBAM_003670: Competence protein S
 
Bacillus pumilus SAFR-032
 
Bacillus licheniformis DSM 13
 
Anoxybacillus flavithermus WK1
 
Geobacillus kaustophilus HTA426
 
Bacillus cereus ATCC 14579
 
Bacillus halodurans C-125
 
Bacillus clausii KSM-K16
 
Oceanobacillus iheyensis HTE831
 
Paenibacillus sp. JDR-2
Competence protein S
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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