Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Propagation of Fur regulog to Staphylococcus aureus subsp. aureus str. Newman

Reference regulog properties
Source regulog: Fur - Staphylococcaceae
Regulator type: Transcription factor
Regulator family: FUR
Regulation mode: repressor
Biological process: Iron homeostasis
Effector: Iron ion, (Fe2+)
Phylum: Firmicutes
Propagated regulon:
Target genome Staphylococcus aureus subsp. aureus str. Newman
Orthologous TF(s) NWMN_1406
Regulated genes 20
Built upon 106 sites [see more]
Predicted regulatory interactions in Staphylococcus aureus subsp. aureus str. Newman
Locus tag Position Score Sequence
Position: -181
Score: 6.1
Sequence: ATTGATAATGATTCTCACT
Locus tag: NWMN_0059
NWMN_0059 -181 6.1 ATTGATAATGATTCTCACT
Supported by regulated orthologs from reference regulons
Ortholog gene name: sirA
Ortholog function: siderophore staphylobactin ABC transporter, substrate-binding protein SirA
Staphylococcus aureus subsp. aureus N315 SA0111 -181 6.1 ATTGATAATGATTCTCACT
-50 5.5 CGTGATAATGATTCTCATT
Position: -68
Score: 6.1
Sequence: AGTGAGAATCATTATCAAT
Locus tag: NWMN_0060
NWMN_0060 -68 6.1 AGTGAGAATCATTATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: sbnA
Ortholog function: Siderophore staphylobactin biosynthesis protein SbnA
Staphylococcus aureus subsp. aureus N315 SA0112 -199 5.5 AATGAGAATCATTATCACG
-68 6.1 AGTGAGAATCATTATCAAT
Position: -158
Score: 5.7
Sequence: TTTGATAATTATTATCAAC
Locus tag: NWMN_0336
NWMN_0336 -158 5.7 TTTGATAATTATTATCAAC
Supported by regulated orthologs from reference regulons
Ortholog gene name: efeO
Ortholog function: Ferrous iron transport periplasmic protein EfeO
Staphylococcus aureus subsp. aureus N315 SA0331 -157 5.7 TTTGATAATTATTATCAAC
Staphylococcus capitis SK14 STACA0001_1108 -93 6.8 ATTGATAATGATTATCAAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_2215 -69 6.6 ATTGATAACGATTATCAAT
Staphylococcus haemolyticus JCSC1435 SH0684 -158 6.5 TTTGATAATGATTATCAAT
Position: -67
Score: 6.1
Sequence: ATTGATAATAATTATCGTT
Locus tag: NWMN_0340
NWMN_0340 -67 6.1 ATTGATAATAATTATCGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: tatA
Ortholog function: putative sec-independant protein translocase
Staphylococcus aureus subsp. aureus N315 SA0335 -67 6.3 ATTGATAATCATTATCGTT
Staphylococcus capitis SK14 STACA0001_1113 -71 6.3 ATTGATAATCTTTATCAAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_2211a -63 6.2 ATTGATAATCTTTATCATT
Staphylococcus haemolyticus JCSC1435 SH0688 -70 6.1 ATTGATAATATTTATCAAT
Position: -102
Score: 6.2
Sequence: CATGATAATCATTATCAAT
Locus tag: NWMN_0616
NWMN_0616 -102 6.2 CATGATAATCATTATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhuA
Ortholog function: ferrichrome transport ATP-binding protein FhuA
Staphylococcus aureus subsp. aureus N315 SA0602 -102 6.2 CATGATAATCATTATCAAT
Staphylococcus capitis SK14 STACA0001_0381 -109 6.4 TATGATAATGATTATCAAT
Staphylococcus epidermidis ATCC 12228 SE0421 -119 6.2 TGTGATAATGATTATCAAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_0295 -222 6.4 TATGATAATGATTATCAAT
Staphylococcus haemolyticus JCSC1435 SH2247 -69 6.3 TATGATAATTATTATCAAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP2073 -111 6.3 TATGATAATGATTATCATT
Macrococcus caseolyticus JCSC5402 MCCL_0166 -46 6.8 ATTGATAATCATTATCAAT
Position: -43
Score: 6.7
Sequence: AATGATAATGATTATCATT
Locus tag: NWMN_0702
NWMN_0702 -43 6.7 AATGATAATGATTATCATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: sstA
Ortholog function: putative siderophore ABC transporter permease
Staphylococcus aureus subsp. aureus N315 SA0688 -43 6.7 AATGATAATGATTATCATT
Staphylococcus epidermidis ATCC 12228 SE0515 -78 6.7 AATGATAATCATTATCATT
Staphylococcus carnosus subsp. carnosus TM300 Sca_0381 -78 6.2 AGTGATAATGATTATCAGT
Staphylococcus haemolyticus JCSC1435 SH2160 -68 6.2 AATGATAATCATTATCGTT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP1984 -75 6.4 ATTGATAATGATTATCATA
Macrococcus caseolyticus JCSC5402 MCCL_1838 -33 6.4 ATTGATAACTATTATCAAT
Position: -41
Score: 5.6
Sequence: ATTGAGAAGTATTATCATT
Locus tag: NWMN_0773
NWMN_0773 -41 5.6 ATTGAGAAGTATTATCATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: SA0757
Ortholog function: putative NAD(P)H nitroreductase
Staphylococcus aureus subsp. aureus N315 SA0757 -41 5.6 ATTGAGAAGTATTATCATT
Staphylococcus capitis SK14 STACA0001_0225 -42 5.8 ATTGATAATTGTTATCAAC
Staphylococcus epidermidis ATCC 12228 SE0593 -44 6 ATTGATAATGGTTATCATG
Staphylococcus carnosus subsp. carnosus TM300 Sca_0449 -39 6.7 AATGATAATGATTATCATT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP1872 -38 6 ATTGAAAATAGTTATCATT
Macrococcus caseolyticus JCSC5402 MCCL_0533 -41 6.4 ATTGATAATAGTTATCAAT
Position: -52
Score: 6.5
Sequence: ATTGATAATGATTATCAGT
Locus tag: NWMN_1040
NWMN_1040 -52 6.5 ATTGATAATGATTATCAGT
Supported by regulated orthologs from reference regulons
Ortholog gene name: isdB
Ortholog function: cell surface receptor IsdB for hemoglobin-haptoglobin complexes
Staphylococcus aureus subsp. aureus N315 SA0976 -52 6.5 ATTGATAATGATTATCAGT
Position: -158
Score: 6.3
Sequence: AATAATAATGATTATCATT
Position: -152
Score: 5.6
Sequence: AATGATTATCATTGTCAAT
Position: -79
Score: 6.6
Sequence: ATTGATAACCATTATCAAT
Locus tag: NWMN_1041
NWMN_1041 -158 6.3 AATAATAATGATTATCATT
-152 5.6 AATGATTATCATTGTCAAT
-79 6.6 ATTGATAACCATTATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: isdA
Ortholog function: iron Transport-associated domain family
Staphylococcus aureus subsp. aureus N315 SA0977 -158 6.3 AATAATAATGATTATCATT
-79 6.6 ATTGATAACCATTATCAAT
Staphylococcus capitis SK14 STACA0001_2139 -46 5.7 ATTGATAAATAATATCAAT
Position: -148
Score: 6.6
Sequence: ATTGATAATGGTTATCAAT
Position: -75
Score: 5.6
Sequence: ATTGACAATGATAATCATT
Position: -69
Score: 6.3
Sequence: AATGATAATCATTATTATT
Locus tag: NWMN_1042
NWMN_1042 -148 6.6 ATTGATAATGGTTATCAAT
-75 5.6 ATTGACAATGATAATCATT
-69 6.3 AATGATAATCATTATTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: isdC
Ortholog function: iron-regulated surface determinant protein C (Staphylococcaliron-regulated protein D)
Staphylococcus aureus subsp. aureus N315 SA0978 -148 6.6 ATTGATAATGGTTATCAAT
-69 6.3 AATGATAATCATTATTATT
Staphylococcus capitis SK14 STACA0001_2141 -86 5.4 GTTGATAACTATTTTCATT
Position: -198
Score: 6.3
Sequence: ATTGATAATTATTCTCAAT
Locus tag: NWMN_1263
NWMN_1263 -198 6.3 ATTGATAATTATTCTCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: citB
Ortholog function: aconitate hydratase
Staphylococcus aureus subsp. aureus N315 SA1184 -198 6.3 ATTGATAATTATTCTCAAT
Staphylococcus capitis SK14 STACA0001_1597 -198 6.1 ATTGATAACCATTCTCAAT
Staphylococcus epidermidis ATCC 12228 SE1032 -198 6.1 ATTGATAACCATTCTCAAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_0991 -190 5.6 ATTGAAAACAATTCTCAAT
Staphylococcus haemolyticus JCSC1435 SH1558 -202 6 AATGAAAATCATTCTCAAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP1408 -193 4.8 GCTGATAATGATTCTCAAC
Position: -50
Score: 6.7
Sequence: ATTGATAATTATTATCAAT
Locus tag: NWMN_1624
NWMN_1624 -50 6.7 ATTGATAATTATTATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: isdH
Ortholog function: cell surface receptor IsdH for hemoglobin-haptoglobin complexes
Staphylococcus aureus subsp. aureus N315 SA1552 -50 6.7 ATTGATAATTATTATCAAT
Position: -198
Score: 5.7
Sequence: AATTATAATCATTCTCATT
Position: -167
Score: 5.8
Sequence: AATGATATTTATTCTCAAT
Position: -94
Score: 5.5
Sequence: AATTATAATTATTATTATT
Locus tag: NWMN_1831
NWMN_1831 -198 5.7 AATTATAATCATTCTCATT
-167 5.8 AATGATATTTATTCTCAAT
-94 5.5 AATTATAATTATTATTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ftnA
Ortholog function: ferritin
Staphylococcus aureus subsp. aureus N315 SA1709 -198 5.7 AATTATAATCATTCTCATT
-167 5.8 AATGATATTTATTCTCAAT
-94 5.5 AATTATAATTATTATTATT
Staphylococcus capitis SK14 STACA0001_1946 -111 5.2 AATGAGAATGGTTATCTCT
Staphylococcus epidermidis ATCC 12228 SE1578 -128 5.2 AATTAGAATAATTATTAAT
Staphylococcus haemolyticus JCSC1435 SH1060 -101 4.9 GATTATAATAATTATTATT
Position: -41
Score: 6
Sequence: ATTGAAAATGAATATCAAT
Locus tag: NWMN_1931
NWMN_1931 -41 6 ATTGAAAATGAATATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhuD5
Ortholog function: ferric hydroxamate binding protein of ABC transporter
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0422 -93 5.7 ATTGATAATCGTTTTCGAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0529 -68 6.6 ATTGATAACGATTATCAAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP1382 -69 6.4 ATTGATAATCAATATCAAT
Macrococcus caseolyticus JCSC5402 MCCL_0133 -32 6.4 AATGATAATCAATATCAAT
Position: -59
Score: 6.3
Sequence: AATGATAATTGTTATCAAT
Locus tag: NWMN_2078
NWMN_2078 -59 6.3 AATGATAATTGTTATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yfmC
Ortholog function: iron(III) dicitrate ABC transporter binding protein
Staphylococcus aureus subsp. aureus N315 SA1979 -59 6.3 AATGATAATTGTTATCAAT
Staphylococcus capitis SK14 STACA0001_1300 -60 6.1 AATGAGAATCGTTATCAAT
Staphylococcus epidermidis ATCC 12228 SE1768 -52 6.1 ATTGAGAATCGTTATCAAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_1680 -192 6.1 AATGAGAATCGTTATCAAT
Staphylococcus haemolyticus JCSC1435 SH0863 -62 6.6 ATTGATAATCGTTATCAAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0709 -61 6 ACCGATAATCATTATCAAT
Position: -45
Score: 5.9
Sequence: AATGATAATGATTCTTATT
Locus tag: NWMN_2081
NWMN_2081 -45 5.9 AATGATAATGATTCTTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: SA1982
Ortholog function: putative permease of the major facilitator superfamily
Staphylococcus aureus subsp. aureus N315 SA1982 -45 5.9 AATGATAATGATTCTTATT
Staphylococcus capitis SK14 STACA0001_1297 -41 6.6 AATGATAATTATTATCAAT
Staphylococcus epidermidis ATCC 12228 SE1771 -40 6.6 AATGATAATTATTATCAAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_1683 -42 6.8 AATGATAATCATTATCAAT
Staphylococcus haemolyticus JCSC1435 SH0860 -54 6.4 AATGATATTCATTATCAAT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0706 -38 6.6 AATGATAATTATTATCAAT
Position: -75
Score: 5.9
Sequence: AATAAGAATCATTATCATT
Locus tag: NWMN_2082
NWMN_2082 -75 5.9 AATAAGAATCATTATCATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: iucB
Ortholog function: putative aerobactin biosynthesis protein, IucA/IucC family
Staphylococcus aureus subsp. aureus N315 SA1983 -75 5.9 AATAAGAATCATTATCATT
Staphylococcus capitis SK14 STACA0001_1296 -82 6.6 ATTGATAATAATTATCATT
Staphylococcus epidermidis ATCC 12228 SE1772 -81 6.6 ATTGATAATAATTATCATT
Staphylococcus carnosus subsp. carnosus TM300 Sca_1684 -83 6.8 ATTGATAATGATTATCATT
Staphylococcus haemolyticus JCSC1435 SH0859 -79 6.4 ATTGATAATGAATATCATT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0705 -83 6.6 ATTGATAATAATTATCATT
Position: -30
Score: 6.5
Sequence: ATTGATAATCATTTTCAAT
Locus tag: NWMN_2185
NWMN_2185 -30 6.5 ATTGATAATCATTTTCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: fhuD2
Ortholog function: ferric hydroxamate binding protein of ABC transporter
Staphylococcus aureus subsp. aureus N315 SA2079 -30 6.5 ATTGATAATCATTTTCAAT
Staphylococcus capitis SK14 STACA0001_1209 -31 6.3 ATTGATAATCGTTATCACT
Staphylococcus carnosus subsp. carnosus TM300 Sca_1778 -36 6.1 AATGATAATCGTTTTCAAT
Staphylococcus haemolyticus JCSC1435 SH0768 -30 5.6 ATTGATAATCGTTTTCAAC
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0623 -30 6.1 ACTGATAATCATTTTCAAT
Position: -70
Score: 6.6
Sequence: AATGATAATAATTATCAAT
Locus tag: NWMN_2274
NWMN_2274 -70 6.6 AATGATAATAATTATCAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: trxB
Ortholog function: ferredoxin--NADP reductase
Staphylococcus aureus subsp. aureus N315 SA2162 -110 6.6 AATGATAATAATTATCAAT
Staphylococcus capitis SK14 STACA0001_1105 -62 6.3 AATGATAATAATTATCACT
Staphylococcus carnosus subsp. carnosus TM300 Sca_1872 -58 5.3 GTTGAGAATAATTTTCAAT
Staphylococcus haemolyticus JCSC1435 SH0681 -51 6.5 AATGATAATAATTATCATT
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 SSP0530 -68 6.6 ATTGATAATCGTTATCAAT
Macrococcus caseolyticus JCSC5402 MCCL_0165 -79 6.8 ATTGATAATGATTATCAAT
Position: -280
Score: 6.1
Sequence: AGTGATAATGATTATTATT
Locus tag: NWMN_2450
NWMN_2450 -280 6.1 AGTGATAATGATTATTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: feoB
Ortholog function: ferrous iron transport protein B
Staphylococcus aureus subsp. aureus N315 SA2337 -41 6.1 AGTGATAATGATTATTATT
Staphylococcus capitis SK14 STACA0001_0946 -42 6.4 ATTGATAATGATTATTAAT
Staphylococcus epidermidis ATCC 12228 SE2114 -36 6.4 AATGATAATGATTATTAAT
Staphylococcus carnosus subsp. carnosus TM300 Sca_2029 -51 6.2 ATTGATAATAATAATCAAT
Macrococcus caseolyticus JCSC5402 MCCL_1625 -268 6.3 ATTGAAAATAATTATCAAT