Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes

-- version 1.7 --

Collections of manually curated regulons grouped together by similar properties such as taxonomic group, transcription factor or transcription factor family, biological process or metabolic pathway.

Complete list of manually curated regulogs available for browsing. Regulogs can be listed either by transcription factor name or by genome name.

The reconstructed regulons in this collection mainly include genes encoding catabolic enzymes and associated uptake transporters that participate in the carbohydrate utilization metabolic pathways.

This section of the database represents the results of accurate automatic propagation of the manually curated regulons to novel closely related genomes.

For each regulog, the propagation procedure checks for the presence of orthologs for both a transcription factor gene and target genes (regulog members), and then performs search for candidate TF-binding sites in upstream regions of orthologous target genes

This procedure is considered to be accurate and conservative since it relies on the manually curated regulons and does not make an attempt for automatic prediction of new members of regulon.