Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for CodY transcription factor family

General statistics
TF regulogs 3
TF regulons 33
TF binding sites 1234

Pleiotropic transcription regulator CodY was characterized in various Gram-positive bacteria as a repressor of the stationary-phase and sporulation genes and an activator of other genes, e.g. those are involved in the carbon overflow metabolism [16531115]. Many of CodY-regulated genes are involved in nitrogen- or carbon metabolism, virulence-assotitation gene expression, transport of macromolecules and transcriptional regulation [20363936, 21097623].The repressor function of CodY is modulated by two different effectors, GTP and branched-chain amino acids (isoleucine, leucine, and valine) [21097623], which may be viewed as sensors of the energetic and metabolic status of the cell, respectively [16488888]. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Firmicutes CodY - Bacillales 11 (11) 445
Firmicutes CodY - Staphylococcaceae 7 (7) 516
Firmicutes CodY - Streptococcaceae 15 (15) 273