Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for Rrf2 transcription factor family

General statistics
TF regulogs 48
TF regulons 331
TF binding sites 1233

Rrf2 family of transcription factors comprises widespread in Bacteria family of regulators that control diverse metabolic processes including (i) FeS cluster biogenesis (IscR) [16677314], (ii) nitric oxide-detoxification systems (NsrR) [16261196], (iii) iron uptake (RirA) [17173478], (iv) cysteine metabolism (CymR) [21624051] and photosynthesis [19692537]. DNA binding activity of Rrf2-family regulators is controlled via diverse mechanisms. In CymR regulator, the activation is achieved through protein-protein interaction with the protein that directly senses the cysteine pool in the cell [21624051]. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Firmicutes CymR - Bacillales 11 (11) 65
Firmicutes CymR - Clostridia-1 5 (8) 16
Firmicutes CymR - Staphylococcaceae 7 (7) 69
Proteobacteria/delta DVU1964/DVU1967 - Desulfovibrionales 6 (10) 16
Proteobacteria/delta HmcR - Desulfovibrionales 6 (10) 12
Firmicutes IscR - Clostridia-1 8 (8) 19
Firmicutes IscR - Clostridia-2 3 (3) 7
Firmicutes IscR - Clostridia-3 9 (14) 9
Proteobacteria IscR - Alteromonadales 9 (9) 43
Proteobacteria IscR - Burkholderia 8 (8) 16
Proteobacteria IscR - Caulobacterales 4 (4) 4
Proteobacteria IscR - Comamonadaceae 11 (11) 16
Proteobacteria IscR - Desulfuromonadales 6 (9) 8
Proteobacteria IscR - Moraxellaceae 4 (4) 4
Proteobacteria IscR - Oceanospirillales/Alteromonadales 12 (12) 41
Proteobacteria IscR - Pasteurellales 9 (9) 22
Proteobacteria IscR - Pseudomonadaceae 8 (8) 15
Proteobacteria IscR - Psychromonadaceae/Aeromonadales 6 (6) 14
Proteobacteria IscR - Rhodospirillales 5 (9) 5
Proteobacteria IscR - Sphingomonadales 7 (7) 7
Proteobacteria IscR - Various betaproteobacteria 12 (12) 27
Proteobacteria IscR - Vibrionales 10 (10) 39
Proteobacteria IscR - Xanthomonadales 4 (4) 4
Proteobacteria/Alpha IscR - Rhodobacterales 14 (15) 125
Proteobacteria/beta IscR - Ralstonia 6 (6) 12
Proteobacteria/gamma IscR - Enterobacteriales 12 (12) 45
Proteobacteria/gamma IscR - Shewanellaceae 16 (16) 93
Proteobacteria IscR2 - Rhodospirillales 7 (9) 7
Firmicutes NsrR - Bacillales 8 (11) 30
Proteobacteria/alpha NsrR - Caulobacterales 2 (4) 3
Proteobacteria/alpha NsrR - Rhizobiales 1 (15) 2
Proteobacteria/alpha NsrR - Rhodobacterales 5 (15) 17
Proteobacteria/alpha NsrR - Rhodospirillales 5 (9) 13
Proteobacteria/alpha NsrR - Sphingomonadales 2 (7) 5
Proteobacteria/beta NsrR - Burkholderia 8 (8) 23
Proteobacteria/beta NsrR - Comamonadaceae 5 (11) 15
Proteobacteria/beta NsrR - Neisseriales 1 (12) 5
Proteobacteria/beta NsrR - Ralstonia 6 (6) 23
Proteobacteria/gamma NsrR - Alteromonadales 1 (9) 2
Proteobacteria/gamma NsrR - Enterobacteriales 11 (12) 73
Proteobacteria/gamma NsrR - Moraxellaceae 3 (4) 7
Proteobacteria/gamma NsrR - Oceanospirillales/Alteromonadales 4 (12) 8
Proteobacteria/gamma NsrR - Psychromonadaceae/Aeromonadales 2 (6) 5
Proteobacteria/gamma NsrR - Shewanellaceae 16 (16) 51
Proteobacteria/gamma NsrR - Vibrionales 8 (10) 40
Proteobacteria/beta NsrR2 - Various betaproteobacteria 6 (12) 16
Proteobacteria RirA - Rhizobiales 9 (15) 129
Proteobacteria/delta TmcR - Desulfovibrionales 3 (10) 6