Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for ModE transcription factor family

General statistics
TF regulogs 37
TF regulons 156
TF binding sites 371

ModE is a dual regulator that controls transcription of genes involved in the homeostasis of molybdenum. ModE-dependent regulation was experimentally characterized in Escherichia coli. ModE regulon includes molybdenum transporters, genes involved in the synthesis of molybdenum cofactors (e.g., molybdopterin guanine dinucleotide in E. coli), and some molybdenum-containing enzymes [19772354, 9325422]. ModE binds molybdate (form of soluble molybdenum) as an effector. Efficient DNA-binding requires protein dimerization and molybdate binding, leading to extensive conformational changes and largely enhanced affinity for specific operator sequences. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/Beta FdsR - Alcaligenaceae 3 (3) 9
Proteobacteria/Beta FdsR - Burkholderia 8 (8) 27
Proteobacteria/Beta FdsR - Comamonadaceae 2 (11) 4
Proteobacteria/Beta FdsR - Ralstonia 4 (6) 14
Proteobacteria/Gamma FdsR - Oceanospirillales/Alteromonadales 1 (12) 4
Proteobacteria/Gamma FdsR - Pseudomonadaceae 1 (8) 4
Chlorobi ModE - Chlorobiales 10 (11) 25
Proteobacteria/Alpha ModE - Rhizobiales 1 (15) 2
Proteobacteria/Apha ModE - Rhodobacterales 1 (15) 3
Proteobacteria/alpha ModE - Caulobacterales 2 (4) 5
Proteobacteria/alpha ModE - Rhizobiales 9 (15) 12
Proteobacteria/alpha ModE - Rhodospirillales 2 (9) 7
Proteobacteria/beta ModE - Alcaligenaceae 3 (3) 3
Proteobacteria/beta ModE - Burkholderia 7 (8) 8
Proteobacteria/beta ModE - Comamonadaceae 6 (11) 10
Proteobacteria/beta ModE - Ralstonia 6 (6) 8
Proteobacteria/beta ModE - Various betaproteobacteria 2 (12) 3
Proteobacteria/delta ModE - Desulfuromonadales 7 (9) 10
Proteobacteria/gamma ModE - Enterobacteriales 12 (12) 55
Proteobacteria/gamma ModE - Moraxellaceae 1 (4) 1
Proteobacteria/gamma ModE - Oceanospirillales/Alteromonadales 2 (12) 2
Proteobacteria/gamma ModE - Pasteurellales 6 (9) 21
Proteobacteria/gamma ModE - Pseudomonadaceae 8 (8) 9
Proteobacteria/gamma ModE - Psychromonadaceae/Aeromonadales 2 (6) 3
Proteobacteria/gamma ModE - Shewanellaceae 5 (16) 10
Proteobacteria/gamma ModE - Vibrionales 2 (10) 2
Bacteroidetes ModE2 - Flavobacteria 2 (19) 2
Proteobacteria/Beta ModE2 - Burkholderia 4 (8) 10
Proteobacteria/Beta ModE2 - Comamonadaceae 5 (11) 8
Proteobacteria/Beta ModE2 - Various betaproteobacteria 2 (12) 4
Proteobacteria/alpha ModE2 - Rhodobacterales 4 (15) 5
Proteobacteria/alpha ModE2 - Rhodospirillales 2 (9) 2
Proteobacteria/alpha ModE2 - Sphingomonadales 2 (7) 2
Proteobacteria/delta ModE2 - Desulfovibrionales 7 (10) 48
Proteobacteria/Beta ModE3 - Alcaligenaceae 2 (3) 5
Proteobacteria/Beta ModE3 - Comamonadaceae 7 (11) 12
Proteobacteria/Beta ModE3 - Ralstonia 6 (6) 12