Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for MetJ transcription factor family

General statistics
TF regulogs 6
TF regulons 62
TF binding sites 1026

MetJ regulators are transcriptional repressors of genes involved in methionine and S-adenosylmethionine biosynthesis and methionine uptake in Gammaproteobacteria. MetJ repressor recognizes its binding sites that are organized as tandem repeats of an 8 bp sequence (the met-box), which varies around a consensus sequence of dAGACGTCT. There are two to five such sequences tandemly repeated in natural operators. In the presence of effector, S-adenosylmethionine, DNA-affinity of the regulator highly increases [20196619]. MetJ regulators are characterized by a ribbon-helix-helix (RHH) DNA binding motif (PF01340) [16515535]. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/Gamma MetJ - Alteromonadales 9 (9) 110
Proteobacteria/Gamma MetJ - Enterobacteriales 12 (12) 167
Proteobacteria/Gamma MetJ - Pasteurellales 9 (9) 50
Proteobacteria/Gamma MetJ - Psychromonadaceae/Aeromonadales 6 (6) 84
Proteobacteria/Gamma MetJ - Vibrionales 10 (10) 218
Proteobacteria/gamma MetJ - Shewanellaceae 16 (16) 397