Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for NiaR transcription factor family

General statistics
TF regulogs 7
TF regulons 57
TF binding sites 109

NiaR regulators control the NAD biosynthesis and salvage of niacin (vitamin B3) in Firmicutes and Thermotogales [18276644]. It was originally investigated in Bacillus subtilis as a niacin-responsive repressor, which binds to its DNA targets in the presence of niacin [16199587]. NiaR regulators constitute a unique protein family, which is characterized by an N-terminal HTH DNA binding domain (PF08279) and a C-terminal effector binding domain, termed the 3H domain (PF02829).

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Firmicutes NiaR - Bacillales 9 (11) 26
Firmicutes NiaR - Clostridia-1 7 (8) 13
Firmicutes NiaR - Clostridia-2 2 (3) 9
Firmicutes NiaR - Clostridia-3 13 (14) 18
Firmicutes NiaR - Lactobacillaceae 5 (15) 7
Firmicutes NiaR - Streptococcaceae 13 (15) 23
Thermotogae NiaR - Thermotogales 8 (11) 13