Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for FUR transcription factor family

General statistics
TF regulogs 77
TF regulons 631
TF binding sites 5295

Fur family of transcription factors includes metal ion-dependent regulators that maintain the iron, manganese, zinc and nickel homeostasis (Fur, Mur, Zur, Nur), or control the oxidative stress response in Bacteria (PerR) [17216355, 11282473, 18259067]. The Fur-family regulators are activated by metal binding to two distinct binding sites. The histidine-rich motif is involved in the cellular response to iron, while the four conserved cysteine motif binds zinc. The metal bound regulators form tight complexes with the promoter regions of their target genes, thus repressing or activating their expression, depending on location of the binding sites. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Bacteroidetes Fur - Bacteroidaceae 11 (11) 11
Cyanobacteria Fur - Cyanobacteria 13 (14) 167
Firmicutes Fur - Bacillales 11 (11) 200
Firmicutes Fur - Clostridia-2 3 (3) 24
Firmicutes Fur - Clostridia-3 12 (14) 49
Firmicutes Fur - Enterococcaceae 2 (2) 14
Firmicutes Fur - Listeriaceae 4 (4) 91
Firmicutes Fur - Staphylococcaceae 7 (7) 106
Firmicutes Fur - Thermoanaerobacterales 7 (7) 29
Proteobacteria Fur - Caulobacterales 4 (4) 38
Proteobacteria Fur - Pasteurellales 9 (9) 151
Proteobacteria Fur - Rhodospirillales 9 (9) 103
Proteobacteria Fur - Shewanellaceae 16 (16) 505
Proteobacteria Fur - Sphingomonadales 7 (7) 74
Proteobacteria/Alpha Fur - Rhodobacterales 2 (15) 27
Proteobacteria/Gamma Fur - Alteromonadales 9 (9) 142
Proteobacteria/Gamma Fur - Psychromonadaceae/Aeromonadales 6 (6) 111
Proteobacteria/Gamma Fur - Vibrionales 10 (10) 447
Proteobacteria/Gamma Fur - Xanthomonadales 4 (4) 49
Proteobacteria/beta Fur - Ralstonia 6 (6) 94
Proteobacteria/delta Fur - Desulfovibrionales 10 (10) 193
Proteobacteria/delta Fur - Desulfuromonadales 9 (9) 41
Proteobacteria/gamma Fur - Enterobacteriales 12 (12) 656
Thermotogae Fur - Thermotogales 10 (11) 26
Proteobacteria/alpha Irr - Rhizobiales 15 (15) 122
Proteobacteria/alpha Irr - Rhodobacterales 12 (15) 37
Proteobacteria/alpha Irr - Rhodospirillales 5 (9) 13
Proteobacteria Mur - Rhizobiales 14 (15) 28
Proteobacteria Mur - Rhodobacterales 13 (15) 28
Actinobacteria Nur - Streptomycetaceae 4 (4) 9
Bacteroidetes PerR - Bacteroidaceae 11 (11) 51
Cyanobacteria PerR - Cyanobacteria 6 (14) 20
Firmicutes PerR - Bacillales 11 (11) 129
Firmicutes PerR - Lactobacillaceae 9 (15) 49
Firmicutes PerR - Staphylococcaceae 7 (7) 69
Firmicutes PerR - Streptococcaceae 13 (15) 75
Proteobacteria/delta PerR - Desulfovibrionales 8 (10) 29
Actinobacteria Zur - Actinobacteria 19 (20) 69
Actinobacteria Zur - Bifidobacteriaceae 10 (10) 33
Actinobacteria Zur - Corynebacteriaceae 8 (8) 38
Actinobacteria Zur - Frankineae/Propionibacterineae/Pseudonocardiaceae 7 (9) 24
Actinobacteria Zur - Micrococcineae 13 (14) 40
Actinobacteria Zur - Mycobacteriaceae 9 (9) 70
Actinobacteria Zur - Nocardiaceae 4 (4) 31
Actinobacteria Zur - Streptomycetaceae 4 (4) 19
Bacteroidetes Zur - Bacteroidaceae 11 (11) 25
Chloroflexi Zur - Chloroflexia 5 (5) 19
Cyanobacteria Zur - Cyanobacteria 14 (14) 84
Firmicutes Zur - Bacillales 11 (11) 67
Firmicutes Zur - Clostridia-1 8 (8) 46
Firmicutes Zur - Enterococcaceae 2 (2) 11
Firmicutes Zur - Lactobacillaceae 11 (15) 43
Firmicutes Zur - Listeriaceae 4 (4) 24
Firmicutes Zur - Staphylococcaceae 7 (7) 56
Proteobacteria Zur - Alteromonadales 9 (9) 46
Proteobacteria Zur - Burkholderia 8 (8) 22
Proteobacteria Zur - Caulobacterales 4 (4) 16
Proteobacteria Zur - Comamonadaceae 5 (11) 11
Proteobacteria Zur - Moraxellaceae 4 (4) 28
Proteobacteria Zur - Rhizobiales 13 (15) 42
Proteobacteria Zur - Rhodobacterales 15 (15) 36
Proteobacteria Zur - Rhodospirillales 9 (9) 27
Proteobacteria Zur - Sphingomonadales 7 (7) 21
Proteobacteria Zur - Various betaproteobacteria 5 (12) 10
Proteobacteria/beta Zur - Ralstonia 6 (6) 19
Proteobacteria/delta Zur - Desulfovibrionales 6 (10) 6
Proteobacteria/delta Zur - Desulfuromonadales 4 (9) 4
Proteobacteria/gamma Zur - Enterobacteriales 12 (12) 65
Proteobacteria/gamma Zur - Oceanospirillales/Alteromonadales 12 (12) 51
Proteobacteria/gamma Zur - Pseudomonadaceae 8 (8) 62
Proteobacteria/gamma Zur - Psychromonadaceae/Aeromonadales 6 (6) 19
Proteobacteria/gamma Zur - Vibrionales 10 (10) 62
Proteobacteria/gamma Zur - Xanthomonadales 4 (4) 14
Thermotogae Zur - Thermotogales 9 (11) 10
Chloroflexi Zur2 - Chloroflexia 2 (5) 10
Proteobacteria Zur2 - Comamonadaceae 2 (11) 3
Proteobacteria Zur2 - Various betaproteobacteria 3 (12) 5